- Skin Protection and Aging
- Circadian rhythm and melatonin
- Epigenetics and DNA Methylation
- melanin and skin pigmentation
- Cerebrovascular and Carotid Artery Diseases
- Autoimmune Neurological Disorders and Treatments
- Antioxidant Activity and Oxidative Stress
- Radiomics and Machine Learning in Medical Imaging
- Ocular Diseases and Behçet’s Syndrome
- Acute Ischemic Stroke Management
- MRI in cancer diagnosis
- Reconstructive Surgery and Microvascular Techniques
- Advanced MRI Techniques and Applications
- Biological and pharmacological studies of plants
- Patient Satisfaction in Healthcare
- Infectious Encephalopathies and Encephalitis
- Protein Degradation and Inhibitors
- Textile materials and evaluations
- Metastasis and carcinoma case studies
- Cardiac, Anesthesia and Surgical Outcomes
- Cancer Immunotherapy and Biomarkers
- Immune Cell Function and Interaction
- Breast Lesions and Carcinomas
- Telomeres, Telomerase, and Senescence
- Bioactive Compounds and Antitumor Agents
Chosun University Hospital
2023
University of Ulsan
2006-2022
Ulsan College
2006-2022
Asan Medical Center
2006-2022
Kangdong Sacred Heart Hospital
2018-2021
Hallym University
2018-2021
Chonbuk National University Hospital
2015-2018
Jeonbuk National University
2010-2018
Jilin University
2017
CUNY School of Law
2017
Tumor-associated lymphocyte numbers in breast cancer have been suggested as a new independent predictor of response to neoadjuvant chemotherapy patients. We therefore evaluated the relationship between pathologic complete (pCR) and tumor-associated lymphocytes tumors such patients.Between 2000 2009, we retrospectively 175 patients with primary treated chemotherapy, followed by definitive surgical resection. Peritumoral lymphocytic infiltration (LI) CD3(+), CD8(+), forkhead box P3 (FOXP3)(+)...
Beneficial effects attributed to green tea, such as its anticancer and antioxidant properties, may be mediated by (-)-epigallocatechin-3-gallate (EGCG). In this study, the of EGCG on cell proliferation UV-induced apoptosis were investigated in normal epidermal keratinocytes. When topically applied aged human skin, stimulated keratinocytes, which increased thickness. addition, topical application also inhibited was found increase phosphorylation Bad protein at Ser112 Ser136. Moreover,...
In Brief Objective: The present study evaluated the oncological safety and technical outcomes following nipple areola skin-sparing mastectomy (NASSM), (SSM), mastectomy. Summary Background Data: Cosmetic issues associated with breast cancer surgery are important. original SSM technique included removal of gland complex (NAC). However, risk tumor involvement NAC has been overestimated. Patients Methods: This retrospective 520 patients who underwent (368 patients) or NASSM (152 immediate...
<h3>Objective</h3> To quantify the distinct effects of photoaging vs intrinsic aging human skin on cutaneous vascularization in Korean population. <h3>Design</h3> Case series. <h3>Setting</h3> University hospital. <h3>Participants</h3> A total 21 healthy volunteers from third to ninth decades life. <h3>Intervention</h3> Skin biopsy specimens were obtained chronically sun-exposed and sun-protected each participant. <h3>Main Outcome Measures</h3> Frozen sections stained for platelet...
Abstract BACKGROUND It has been suggested that cyclin-dependent kinase inhibitors (CDKIs), including p16 and p15, are tumor suppressor genes. Alterations of CDKIs have found in most types cancer. However, little is known about the status p15 genes, methylation promoter region, gastric carcinoma. METHODS Thirty-six primary tumors 9 carcinoma cell lines were examined for alterations Deletion genes was assessed by Southern blot analysis, expression Northern mutation polymerase chain...
In this study, the effects of BST204, a fermented ginseng extract, on expression inducible nitric oxide synthase (iNOS) and (NO) production are looked into. Crude extract was incubated with ginsenoside-beta-glucosidase to prepare BST204. unlike lipopolysaccharide (LPS) crude did not affect level iNOS protein NO in unstimulated RAW 264.7 cells. However, it suppressed LPS-stimulated cells but manifest same effect mRNA level. An investigation activating phosphorylation p70 S6 kinase 4E-BP1,...
Abstract Objective: Our purpose was to rigorously examine the nature of family meetings as conducted in an inpatient hospice care unit order generate inductive theoretical model. Method: In this two-phase project, we first interviewed eight members interdisciplinary team who participated multiple each week. Interview questions explored why and how they meetings. Using observation template created from these interview data, subsequently ethnographic observations during methods grounded...
Thyroid dysfunction has been known to be closely associated with increased vascular events. The aims of the present study included determining prevalence subclinical thyroid disease and relationships between normal ranges function internal carotid artery steno-occlusion (ICS) in patients ischemic stroke. From March 2007 February 2008, 382 consecutive stroke referred neurovascular ultrasound laboratory were analyzed. ICS was defined as greater than 50% luminal narrowing or complete...
In this study, we demonstrate that catalase is differently regulated either by acute, or chronic UV radiation during the photoaging process. 2MED of decreased activity and expression gradually in epidermis dermis at between 24 48 h after exposure. These levels then returned to near normal 72 The mRNA was also skin irradiation 50% control level, started recover. contrast, over a lifetime (approximately 50 years) increased human vivo. Our results suggest might be one important enzymes aging...
This article focuses on the prevention, identification, and management of urinary fecal incontinence in perinatal period. Both are common concerns affecting women throughout pregnancy, intrapartum, postpartum. These problems that not approached by healthcare providers during initial antepartal assessment, nor they fully investigated after delivery. Many hesitate to disclose this information. Women tend consider be a minor discomfort pregnancy consequence resulting from childbirth postpartum...
Robot-assisted rehabilitation therapy of the upper extremity after stroke has been studied widely; however, robotic devices remain expensive and bulky. The aim this study was to evaluate effects a newly developed, compact training system (Neuro-X®) in patients with chronic stroke.Pilot study.Fifteen hemiplegia.Chronic underwent using developed (Neuro-X®; Apsun Inc., Seoul, Korea). Patients were evaluated Fugl-Meyer Assessment (FMA), Hand Function Test (HFT), Modified Ashworth Scale (MAS),...