A5100722778- Traumatic Brain Injury and Neurovascular Disturbances
- Cancer-related molecular mechanisms research
- Meningioma and schwannoma management
- RNA modifications and cancer
- S100 Proteins and Annexins
- Esophageal and GI Pathology
- Kawasaki Disease and Coronary Complications
- Ophthalmology and Eye Disorders
- Traumatic Ocular and Foreign Body Injuries
- Neuroinflammation and Neurodegeneration Mechanisms
- Cerebral Venous Sinus Thrombosis
- Coronary Artery Anomalies
- Vascular Malformations Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Facial Trauma and Fracture Management
- Gastrointestinal disorders and treatments
- Dysphagia Assessment and Management
- Circular RNAs in diseases
- Cerebrovascular and Carotid Artery Diseases
- Gastrointestinal Tumor Research and Treatment
- Anorectal Disease Treatments and Outcomes
- Neuroscience and Neural Engineering
- Trauma Management and Diagnosis
- RNA Research and Splicing
- Traumatic Brain Injury Research
Zhongshan Hospital
2016-2025
Fudan University
2016-2025
South China Institute of Collaborative Innovation
2025
Second Military Medical University
2017-2025
Longhua Hospital Shanghai University of Traditional Chinese Medicine
2025
Shanghai University of Traditional Chinese Medicine
2025
Second Hospital of Anhui Medical University
2025
Anhui Medical University
2025
Shanghai Changzheng Hospital
2015-2024
Children's Hospital of Chongqing Medical University
2020-2021
Abstract Background White matter injury (WMI) represents a significant etiological factor contributing to neurological impairment subsequent Traumatic Brain Injury (TBI). CD36 receptors are recognized as pivotal participants in the pathogenesis of disorders, including stroke and spinal cord injury. Furthermore, dynamic fluctuations phenotypic polarization microglial cells have been intimately associated with regenerative processes within injured tissue following TBI. Nevertheless, there is...
A 68-year-old woman, who was diagnosed with suppurative appendicitis 17 years previously and underwent appendectomy, found during a recent colonoscopy, performed as part of health-check, to have 1.5-cm flat laterally spreading tumor (LST) at the appendiceal orifice ([Fig. 1] a). Biopsy indicated that lesion tubular adenoma low grade intraepithelial neoplasia (LGIN). Computed tomography revealed peristump exudation pneumatosis. Endoscopic transcecal appendectomy (ETA) recommended remove stump...
Background: Paroxysmal sympathetic hyperactivity (PSH) is one of the important reasons for high mortality and morbidity traumatic brain injury (TBI). We aim to explore role neutrophil extracellular traps (NETs) in pathogenesis hyperexcitability after TBI underlying mechanisms, providing evidence clinical treatment. Methods: Enzyme-linked immunosorbent assay was used assess plasma metanephrine normetanephrine levels which represented variation system with rat diffuse axonal (DAI) model. NETs...
Inflammation plays an essential role in eliminating microbial pathogens and repairing tissues, while sustained inflammation accelerates kidney damage disease progression. Therefore, understanding the mechanisms of inflammatory response is vital for developing therapies diseases like acute injury (AKI), which currently lacks effective treatment. Here, we identified N-acetyltransferase 10 ( NAT10 ) as important regulator inflammation. , only known “writer” protein N4-acetylcytidine (ac4C)...
Traumatic brain injury (TBI), particularly diffuse axonal (DAI), often results in sympathetic hyperactivity, which can exacerbate the prognosis of TBI patients. A key component this process is role neutrophils causing neuroinflammation after by forming neutrophil extracellular traps (NETs), but connection between NETs and excitation following remains unclear. Utilizing a DAI rat model, current investigation examined HMGB1/JNK/AP1 signaling pathway process. The findings revealed that...
Messager RNA (mRNA) can be modified in a variety of ways, among which the modification N6-methyladenosine (m6A) is one most common ones. Recent studies have found that m6A mRNA could functionally regulate splicing, localization, translation, and stability mRNA, might closely related to multiple diseases. However, roles traumatic optic neuropathy (TON) are unknown. Herein, we detected expression m6A-related genes via quantitative real-time PCR (qRT-PCR) performed methylated...
Oral squamous cell carcinoma (OSCC) is a prevalent of the head, neck and mouth. Recently studies involving role long noncoding RNAs (lncRNAs) that play key regulatory roles in altering gene expression has been reported context promoting tumorigenesis. However, functions lncRNAs oral have not extensively described. In this study, we report never identified before lncRNA, LINC00941, which was highly expressed OSCC tissues cells. Expression LINC00941 promoted proliferation, migration, invasion,...