A5013587522- Malaria Research and Control
- Travel-related health issues
- Mosquito-borne diseases and control
- Parasites and Host Interactions
- Dementia and Cognitive Impairment Research
- Zoonotic diseases and public health
- Frailty in Older Adults
- Chronic Disease Management Strategies
- Vector-borne infectious diseases
- Aging, Elder Care, and Social Issues
- Computational Drug Discovery Methods
- Nutritional Studies and Diet
- Medicinal plant effects and applications
- Healthcare and Venom Research
- Dermatological diseases and infestations
- Aging, Health, and Disability
- Parasitic Diseases Research and Treatment
- Digital Imaging for Blood Diseases
- Mental Health Treatment and Access
- Mental Health and Psychiatry
- Cardiac Health and Mental Health
- Healthcare professionals’ stress and burnout
- Parasitic Infections and Diagnostics
- Hepatitis Viruses Studies and Epidemiology
- Health disparities and outcomes
Hospital Universitario Príncipe de Asturias
2013-2024
Universidad de Alcalá
2023-2024
Universidad de Zaragoza
2006-2022
Instituto de Investigación Sanitaria Aragón
2014-2022
Centro de Investigación Biomédica en Red de Salud Mental
2008-2018
Vall d'Hebron Hospital Universitari
2015
Hospital Universitario Ramón y Cajal
2015
Instituto Ramón y Cajal de Investigación Sanitaria
2015
Hospital Universitario de Fuenlabrada
2015
Hospital General Universitario de Alicante Doctor Balmis
2015
To compare the prevalence of dementia in two different time periods and studies.Representative, random samples elderly (>65 years) Zaragoza Study or ZARADEMP-0 (n = 1080) completed previous decade, now Wave I ZARADEMP Project ZARADEMP-I 3715) were interviewed. Standardized measures included Geriatric Mental State History Aetiology schedule. Cases diagnosed according to DSM-IV criteria.Adjusted, global has not varied significantly: it was 5.2% (95% CI 3.9-6.6) 3.9% 3.3-4.5) (prevalence ratio...
Lobo A, Lopez-Anton R, Santabárbara J, de-la-Cámara C, Ventura T, Quintanilla MA, Roy JF, Campayo AJ, E, Palomo Rodriguez-Jimenez Saz P, Marcos G. Incidence and lifetime risk of dementia Alzheimer's disease in a Southern European population. Objective: To calculate both the incidence rates (LTR) (AD). Methods: A two-phase case-finding procedure was implemented cohort 4057 cognitively intact individuals 55+ years age living Zaragoza, Spain, followed-up at 2.5 4.5 years. Age- sex-specific were...
Objective To contrast the prevalence of mild cognitive impairment ( MCI ) as diagnosed using DSM ‐5 criteria 5‐ with Petersen's (P‐ and to explore association both non‐cognitive psychopathological symptoms NCPS ). Method A two‐phase epidemiological screening was implemented in a population‐based sample individuals aged 55+ n = 4803). The Geriatric Mental State GMS main instrument used, AGECAT used make psychiatric diagnoses. Research psychiatrists P‐ operational criteria. Logistic regression...
Objective To evaluate whether clinically significant anxiety is an independent risk factor for dementia, taking into account both depression among potentially confounding factors and the competing of death. Method During Zaragoza Dementia Depression ( ZARADEMP ) study, a random sample community dwellers aged 55 years or older was assessed n = 4803), two‐wave, 4.5‐year follow‐up completed. Geriatric Mental State GMS )‐ AGECAT criteria were used to diagnose DSM ‐ IV applied incident dementia....
Objective In a background of revision criteria for states increased risk progression to dementia, we compare the conversion rate dementia and Alzheimer's disease ( AD ) mild cognitive impairment MCI as diagnosed using DSM ‐5 ‐5‐ Petersen's (P‐ criteria. Method A population representative cohort 4057 dementia‐free individuals 55+ years age was followed up at 2.5 4.5 in Zaragoza, Spain ZARADEMP ). Using Geriatric Mental State‐ AGECAT assessment, research psychiatrists P‐ following...
Sequencing data from Plasmodium ovale genotypes co-circulating in multiple countries support the hypothesis that P. curtisi and wallikeri are 2 separate species. We conducted a multicenter, retrospective, comparative study Spain of 21 patients who had imported infections 14 confirmed by PCR gene sequencing during June 2005-December 2011. The only significant finding was more severe thrombocytopenia among with infection than those (p = 0.031). However, we also found nonsignificant trends...
The authors evaluated the association of low-to-moderate alcohol consumption with risk cognitive decline in a census-based cohort study men and women aged ≥55 years conducted Zaragoza, Spain (1994-1999). Participants free dementia at baseline (N = 3,888) were examined after 2.5 4.5 follow-up. Information on intake was collected EURODEM Risk Factors Questionnaire History Aetiology Schedule. endpoint severe decline, defined as loss ≥1 point/year Mini-Mental State Examination or diagnosis...
Few previous retrospective studies suggest that Plasmodium ovale wallikeri seems to have a longer latency period and produces deeper thrombocytopaenia than curtisi. Prospective were warranted better assess interspecies differences. Patients with imported P. spp. infection diagnosed by thick or thin film, rapid diagnostic test (RDT) polymerase chain reaction (PCR) recruited between March 2014 May 2017. All confirmed DNA isolation classified as o. curtisi using partial sequencing of the ssrRNA...
The association between occupational exposure and stomach cancer was investigated in a multicenter case-referent study conducted Spain on 354 histologically confirmed cases hospital referents, matched by age, gender, residence. An increased risk of gastric found for coal mining workers [odds ratio (OR) 11.8], but the number small, therefore 95% confidence interval (95% CI) wide CI 1.36-103). observed wood furniture (OR 1.76), construction 1.68), glass ceramic 2.18), none these risks were...
Acute respiratory distress syndrome is a well-known complication in Plasmodium falciparum infection. It less frequently described vivax, and only one case reported ovale. Here we present the second description of this pulmonary P. ovale acute
Microscopy and rapid diagnosis tests have a limited sensitivity in of malaria by Plasmodium ovale. The LAMP kit (LoopAMP®) can be used the field without special equipment could an important role control programmes endemic areas for returned travellers. performance Pan primer detecting P. ovale was compared with results standard nPCR samples patients returning from areas. positive (29, tested PCR and/or microscopy) negative specimens (398, microscopy PCR) were collected different hospitals...
Background Loa loa infection is endemic in limited areas of West-Central Africa. Loiasis has been associated with excess mortality, but clinical studies on its treatment are scant, particularly outside areas, due to the rarity cases diagnosed. Methodology/Principal findings With this retrospective TropNet (European Network for Tropical Medicine and Travel Health) study, we aimed at outlining schedules followed by different reference centers tropical medicine across Europe. We gathered...
Clinical experience and recent population studies suggest that psychopathological, non-cognitive symptoms are both frequent relevant in dementia.A representative community sample (n = 4,803 individuals, 55 + years) was interviewed a two-phase design. The Geriatric Mental Sate (GMS) used for assessment cases were diagnosed according to DSM-IV-TR criteria.The prevalence of (1 symptoms) dementia 223) 90.1%, negative-type most frequently found. A GMS 'apathy-related symptom cluster' (anergia,...
The importance of submicroscopic malaria infections in high-transmission areas could contribute to maintain the parasite cycle. Regarding non-endemic areas, its remains barely understood because parasitaemia these afebrile patients is usually below detection limits for microscopy, hence molecular techniques are often needed diagnosis. In addition this, lack standardized protocols screening immigrants from endemic may underestimate infection with Plasmodium spp. aim this study was assess...
Abstract Background In Spain, the risk of imported malaria has increased in recent years due to rise international travel and migration. Little is known about knowledge, information sources, clinical practice, specific needs primary care physicians (PCPs) concerning despite pivotal role played by these professionals managing health tourists. The objective this study was assess attitudes, practices PCPs Spain regarding malaria. Methods This research analyses data from (1) a cross-sectional...
To test the hypothesis that cognitive impairment in older adults is associated with all-cause mortality risk and increases when degree of augments; then, if this association confirmed, to report population-attributable fraction (PAF) due impairment.A representative random community sample individuals aged over 55 was interviewed, 4557 subjects remaining alive at end first year follow-up were included analysis. Instruments used assessment Mini-Mental Status Examination (MMSE), History...
Gastrointestinal symptoms are a common cause of consultation about children traveling to or coming from developing countries. The aim this study was identify the risk factors associated with gastrointestinal syndrome in who travel.A prospective observational analytical and multicenter performed within +Redivi, Spanish Tropical Medicine network on imported infections, January 2009 December 2013. All participants aged 16 years younger were included analysis. Ethical approval obtained all...
Malaria in pregnancy is associated with maternal and foetal morbidity mortality endemic areas, but information on imported cases to non-endemic areas scarce. The aim of this study was describe the clinical epidemiological characteristics malaria two general hospitals Madrid, Spain. Retrospective descriptive laboratory-confirmed pregnant women at Fuenlabrada University Hospital Príncipe de Asturias Hospital, over a six- 11-year period, respectively. Relevant epidemiological, laboratory data...
We report the first known case of hemophagocytic lymphohistiocytosis (HLH) secondary to imported Plasmodium ovale wallikeri infection in a 58-year-old white woman. A delayed diagnosis malaria and HLH was made after protracted fever pancytopenia failed respond adequately antimalarial treatment, which required intravenous methylprednisolone gamma-globulin therapy resolve.