- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Hepatitis B Virus Studies
- Healthcare Policy and Management
- Pancreatitis Pathology and Treatment
- Primary Care and Health Outcomes
- Hepatocellular Carcinoma Treatment and Prognosis
- Inflammatory Bowel Disease
- Hepatitis C virus research
- Genetic and Kidney Cyst Diseases
- Organ Donation and Transplantation
- Microscopic Colitis
- Alcohol Consumption and Health Effects
- Drug-Induced Hepatotoxicity and Protection
- COVID-19 Clinical Research Studies
- Gastric Cancer Management and Outcomes
- Palliative Care and End-of-Life Issues
- Cytomegalovirus and herpesvirus research
- Renal Transplantation Outcomes and Treatments
- Geriatric Care and Nursing Homes
- Chronic Disease Management Strategies
- Liver physiology and pathology
- Gastrointestinal Tumor Research and Treatment
- Folate and B Vitamins Research
Weill Cornell Medicine
2017-2024
Cornell University
2016-2024
Presbyterian Hospital
2016-2023
New York Hospital Queens
2016-2023
NewYork–Presbyterian Hospital
2016-2023
Center for Digestive and Liver Diseases
2020-2022
Columbia University Irving Medical Center
2014-2021
National Institute of Diabetes and Digestive and Kidney Diseases
2021
ProQuest (United States)
2021
Fundación Juan March
2020
Solid organ transplant recipients may be at a high risk for SARS-CoV-2 infection and poor associated outcomes. We herein report our initial experience with solid two centers during the first 3 weeks of outbreak in New York City. Baseline characteristics, clinical presentation, antiviral immunosuppressive management were compared between patients mild/moderate severe disease (defined as ICU admission, intubation or death). Ninety analyzed median age 57 years. Forty-six kidney recipients, 17...
Recent reports suggest that prevalence of gastrointestinal (GI) and hepatic manifestations in COVID-19 are higher than initially reported, particularly Western populations. New York City has arguably been the epicenter pandemic United States, creating a unique opportunity to further understanding this disease. Our objectives were investigate GI patients with COVID-19, explore their effect on clinical outcomes these patients. This is retrospective review consecutive adult (age ≥18) positive...
The Model for End-Stage Liver Disease score may have eliminated racial disparities on the waitlist liver transplantation (LT), but prior to placement not been adequately quantified. We aimed analyze differences in patients who are listed LT, undergo transplantation, and die from end-stage disease (ESLD), stratified by state race/ethnicity.We analyzed two databases retrospectively, Center Control Wide-ranging Online Data Epidemiologic Research (CDC WONDER) United Network Organ Sharing (UNOS)...
Accurate preoperative prediction of hepatocellular carcinoma (HCC) recurrence after liver transplant is the mainstay selection tools used by transplant-governing bodies to discern candidacy for patients with HCC. Although progress has been made, few incorporate objective measures tumor biological characteristics, resulting in inclusion high rates and exclusion others who could otherwise be cured.To externally validate New York/California (NYCA) score, a recently published multi-institutional...
The COVID-19 pandemic and social justice movement have highlighted the impact of determinants health (SDOH) structural racism in United States on both access to care patient outcomes. With evaluation for liver transplantation being a highly subjective process, there are multiple ways SDOH place vulnerable patients at disadvantage. This policy corner focuses three different methods reverse deleterious effects SDOH-identify reduce implicit bias, expand optimize telemedicine, improve community outreach.
There is growing recognition that chronic liver conditions influence brain health. The impact of fibrosis on dementia risk was unclear. We evaluated the association between and incident in a cohort study.
Although sex and racial disparities for liver transplantation (LT) are known, it is unclear if exist patients with alcohol-associated disease (ALD). We aimed to compare racial/ethnic differences in mortality, LT listing, rates without ALD. analyzed who were listed and/or died of end-stage (ESLD) between 2014 2018 using the United Network Organ Sharing Standard Transplant Analysis Research Centers Disease Control Prevention Wide-ranging OnLine Data Epidemiologic databases, respectively....
Abstract Background and Aim Portal vein thrombosis (PVT) is increasingly common in cirrhotics, but its impact on mortality outcomes unclear. Studies evaluating PVT have been limited by small sample size. This study analyzes the trend of prevalence associated hospitalized decompensated cirrhotics. Methods The Nationwide Inpatient Sample, largest nationally representative database hospital discharges, was queried from 1998 to 2014. Inpatients older than 18 years with cirrhosis were included,...
Inflammatory bowel disease (IBD) is a complex chronic that often requires multispeciality approach; thus, IBD patients are prone to care fragmentation. We aim determine the prevalence of fragmentation among hospitalized and identify associated predictors visit-level outcomes.The State Inpatient Databases for New York Florida were used 90-day readmissions inpatients from 2009 2013. The fragmentation, defined as readmission non-index hospital, was reported. Characteristics with fragmented...
Acute‐on‐chronic liver failure (ACLF) carries high short‐term mortality. The North American Consortium for the Study of End‐Stage Liver Disease (NACSELD)–ACLF score, positive if ≥2 organ failures are present, is a bedside tool that predicts mortality in patients with cirrhosis. However, it was created using major referral centers, where minority cirrhosis hospitalized. Therefore, this study used Nationwide Inpatient Sample, nationally representative database, from 2005 to 2014 externally...
INTRODUCTION: Symptomatic ascites is the most common indication for hospitalization in patients with cirrhosis. Although guidelines recommend paracentesis all inpatients ascites, timing of likely to be crucial. Performance an early and its relationship outcomes are unknown, particularly among at high risk spontaneous bacterial peritonitis (SBP). METHODS: We included 75,462 discharges adult cirrhosis presenting who underwent from State Inpatient Databases New York, Florida, Washington 2009...
Patients with liver diseases, including decompensated cirrhosis, alcohol-associated hepatitis, and transplant recipients are at increased risk of acquiring invasive fungal infections (IFIs). These carry high morbidity mortality. Multiple factors, host immune dysfunction, barrier failures, malnutrition, microbiome alterations, increase the developing IFI. Candida remains most common pathogen causing However, other pathogens, Aspergillus, Cryptococcus, Pneumocystis, endemic mycoses, being...
Opioid use disorder [OUD] has become a public health crisis among patients with chronic disease. Inflammatory bowel disease [IBD] are at high risk for OUD because they suffer from relapsing-remitting pain. We aimed to describe the prevalence and trends in OUD-related diagnoses hospitalised IBD patients. A retrospective study was performed using weighted Nationwide Inpatient Sample data 2005 2014. Adult hospital visits were identified previously published schema. Annual calculated....
Background: Cirrhosis is associated with an increased risk of hemorrhagic stroke. Liver fibrosis, typically a silent condition, antecedent to cirrhosis. The objective this study was test the hypothesis that elevated Fibrosis-4 (FIB-4) index, indicating high probability liver Methods: We performed cohort analysis prospective United Kingdom Biobank study. Participants 40–69 years old were enrolled between 2007 and 2010 had available follow-up data until March 1, 2018. excluded participants...
Liver fibrosis, a common yet often subclinical manifestation of chronic liver disease, may have an unrecognized role in cognitive impairment. We evaluated the association between validated fibrosis index and measures among older adults.We examined performance participants aged 60 years US National Health Nutrition Examination Survey. was measured with Fibrosis-4 (FIB-4) score. The outcomes were on four standardized tests immediate delayed verbal learning, fluency, attention/concentration....
Despite improvement in the care of patients with end‐stage liver disease (ESLD), mortality is rising. In United States, are increasingly choosing to die at hospice and home, but data ESLD lacking. Therefore, this study aimed describe trends location death ESLD. We conducted a retrospective cross‐sectional analysis using Centers for Disease Control Prevention Wide‐Ranging OnLine Data Epidemiologic Research from 2003 2018. Death was categorized as hospice, inpatient facility, nursing or other....
Objectives This study compares the progression of multifocal (MF) intraductal papillary mucinous neoplasms (IPMNs) to unifocal (UF) lesions. Methods We performed a retrospective review demographics, risk factors, and cyst characteristics prospectively maintained database 999 patients with pancreatic cysts. Patients included had IPMN under surveillance for 12 months or more. Those high-risk stigmata were excluded. Cyst size development worrisome features compared between MF UF cohorts....