- Colorectal Cancer Surgical Treatments
- Colorectal and Anal Carcinomas
- Lung Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Genetic factors in colorectal cancer
- Colorectal Cancer Treatments and Studies
Fudan University Shanghai Cancer Center
2020-2024
Shanghai Clinical Research Center
2024
Shanghai Institute of Hematology
2024
Shanghai Medical College of Fudan University
2024
PURPOSE To assess whether the integration of PD-1 inhibitor with total neoadjuvant therapy (iTNT) can lead to an improvement in complete responses (CRs) and favors a watch-and-wait (WW) strategy patients proficient mismatch repair or microsatellite stable (pMMR/MSS) locally advanced rectal cancer (LARC). PATIENTS AND METHODS We conducted prospective, multicenter, randomized, open-label, phase II trial using pick-the-winner design. Eligible clinical T3-4 and/or N+ adenocarcinoma were randomly...
Abstract Background Undetermined lung nodules are common in locally advanced rectal cancer (LARC) and lack precise risk stratification. This study aimed to develop a radiomic‐based score (Rad‐score) distinguish metastasis predict overall survival (OS) patients with LARC nodules. Methods Retrospective data from two institutions (July 10, 2006—September 24, 2015) was used validate the Rad‐score for distinguishing nodule malignancy. The prognostic value of investigated cohorts, leading...