George W. Gokel

ORCID: 0000-0003-3994-6795
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Research Areas
  • Molecular Sensors and Ion Detection
  • Crystallography and molecular interactions
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Inorganic and Organometallic Chemistry
  • Lipid Membrane Structure and Behavior
  • Supramolecular Chemistry and Complexes
  • Analytical Chemistry and Chromatography
  • Ion channel regulation and function
  • Chemical Synthesis and Analysis
  • Electrochemical Analysis and Applications
  • Porphyrin and Phthalocyanine Chemistry
  • Molecular Junctions and Nanostructures
  • Analytical Chemistry and Sensors
  • Microwave-Assisted Synthesis and Applications
  • Chemical Synthesis and Reactions
  • Luminescence and Fluorescent Materials
  • Crystal structures of chemical compounds
  • Ferrocene Chemistry and Applications
  • Mass Spectrometry Techniques and Applications
  • Molecular spectroscopy and chirality
  • Neuroscience and Neuropharmacology Research
  • Chemical Reaction Mechanisms
  • Synthetic Organic Chemistry Methods
  • Supramolecular Self-Assembly in Materials

University of Missouri–St. Louis
2013-2023

Chugai Pharma (United States)
2016

Washington University in St. Louis
2002-2012

University of Missouri
1997-2011

Center for NanoScience
2010

University of Miami
1989-2007

University of Ottawa
2006-2007

Mallinckrodt (United States)
2006

Kansas State University
2006

Max Planck Institute of Colloids and Interfaces
2006

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStereoselective syntheses. VI. Correlation of central and planar chirality in ferrocene derivativesDieter Marquarding, Hans Klusacek, George Gokel, Peter Hoffmann, Ivar UgiCite this: J. Am. Chem. Soc. 1970, 92, 18, 5389–5393Publication Date (Print):September 1, 1970Publication History Published online1 May 2002Published inissue 1 September 1970https://pubs.acs.org/doi/10.1021/ja00721a017https://doi.org/10.1021/ja00721a017research-articleACS...

10.1021/ja00721a017 article EN Journal of the American Chemical Society 1970-09-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHost-guest complexation. 1. Concept and illustrationEvan P. Kyba, Roger C. Helgeson, Khorshed Madan, George W. Gokel, Thomas L. Tarnowski, Stephen S. Moore, Donald J. CramCite this: Am. Chem. Soc. 1977, 99, 8, 2564–2571Publication Date (Print):April 1, 1977Publication History Published online1 May 2002Published inissue 1 April 1977https://pubs.acs.org/doi/10.1021/ja00450a026https://doi.org/10.1021/ja00450a026research-articleACS PublicationsRequest...

10.1021/ja00450a026 article EN Journal of the American Chemical Society 1977-04-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStereoselective syntheses. VIII. Retentive nucleophilic displacements of .alpha.-substituted alkylferrocenesGeorge W. Gokel, Dieter Marquarding, and Ivar K. UgiCite this: J. Org. Chem. 1972, 37, 20, 3052–3058Publication Date (Print):October 1, 1972Publication History Published online1 May 2002Published inissue 1 October 1972https://pubs.acs.org/doi/10.1021/jo00985a002https://doi.org/10.1021/jo00985a002research-articleACS PublicationsRequest reuse...

10.1021/jo00985a002 article EN The Journal of Organic Chemistry 1972-10-01

Protein N-myristoylation refers to the covalent attachment of myristic acid, a 14-carbon saturated fatty acid (C14:0), N-terminal glycine proteins. Linkage occurs via an amide bond and takes place as proteins are being synthesized. N-myristoylproteins have varied intracellular destinations, involved in myriad cellular functions ranging from signal transduction protein vesicular trafficking. encountered members all kingdoms eukaryotic domain (Protist, Fungi, Plant, Animal), but not produced...

10.1016/s0021-9258(18)31490-x article EN cc-by Journal of Biological Chemistry 1991-05-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPreparation and purification of 18-crown-6[1,4,7,10,13,16-hexaoxacyclooctadecane]George W. Gokel, Donald J. Cram, Charles L. Liotta, Henry P. Harris, Fred CookCite this: Org. Chem. 1974, 39, 16, 2445–2446Publication Date (Print):August 1, 1974Publication History Published online1 May 2002Published inissue 1 August 1974https://pubs.acs.org/doi/10.1021/jo00930a037https://doi.org/10.1021/jo00930a037research-articleACS PublicationsRequest reuse...

10.1021/jo00930a037 article EN The Journal of Organic Chemistry 1974-08-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHost-guest complexation. 7. The binaphthyl structural unit in host compoundsEvan P. Kyba, George W. Gokel, Feike De Jong, Kenji Koga, Lynn R. Sousa, Merrell G. Siegel, Lester Kaplan, Dotsevi Y. Sogah, and Donald J. CramCite this: Org. Chem. 1977, 42, 26, 4173–4184Publication Date (Print):December 1, 1977Publication History Published online1 May 2002Published inissue 1 December...

10.1021/jo00862a001 article EN The Journal of Organic Chemistry 1977-12-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFerrocenyl iron as a donor group for complexed silver in ferrocenyldimethyl[2.2]cryptand: redox-switched receptor effective waterJulio C. Medina, Timothy T. Goodnow, Maria Rojas, Jerry L. Atwood, Bert Lynn, Angel E. Kaifer, and George W. GokelCite this: J. Am. Chem. Soc. 1992, 114, 26, 10583–10595Publication Date (Print):December 1, 1992Publication History Published online1 May 2002Published inissue 1 December...

10.1021/ja00052a064 article EN Journal of the American Chemical Society 1992-12-01

The principles involved in macroheterocycle chemistry are discussed. Classes and types of macroheterocycles, synthetic approaches (including the template effect), complexation complexes mentioned. utilization crown ethers organic is also surveyed. 1. Introduction 1.1. History 1.2. Nomenclature Characteristics 1.3. Crowns Related Molecules 2. Synthetic Access 2.1. Templated Syntheses 2.2. Non-Williamson 3. Complexation 3.1. Phenomenon 3.2. Types Complexes 4. Utility 4.1. Solubilization Phase...

10.1055/s-1976-23980 article EN Synthesis 1976-01-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTClarification of the hole-size cation-diameter relationship in crown ethers and a new method for determining calcium cation homogeneous equilibrium binding constantsGeorge W. Gokel, Deepa M. Goli, Carlo Minganti, Luis EchegoyenCite this: J. Am. Chem. Soc. 1983, 105, 23, 6786–6788Publication Date (Print):November 1, 1983Publication History Published online1 May 2002Published inissue 1 November...

10.1021/ja00361a003 article EN Journal of the American Chemical Society 1983-11-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRationalization of the unusual electrochemical behavior observed in lariat ethers and other reducible macrocyclic systemsSteven R. Miller, Deborah A. Gustowski, Zhi Hong. Chen, George W. Gokel, Luis. Echegoyen, Angel E. KaiferCite this: Anal. Chem. 1988, 60, 19, 2021–2024Publication Date (Print):October 1, 1988Publication History Published online1 May 2002Published inissue 1 October...

10.1021/ac00170a007 article EN Analytical Chemistry 1988-10-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT12-, 15-, and 18-Membered-ring nitrogen-pivot lariat ethers: syntheses, properties, sodium ammonium cation binding propertiesRose Ann Schultz, Banita D. White, Dennis M. Dishong, Kristin A. Arnold, George W. GokelCite this: J. Am. Chem. Soc. 1985, 107, 23, 6659–6668Publication Date (Print):November 1, 1985Publication History Published online1 May 2002Published inissue 1 November...

10.1021/ja00309a039 article EN Journal of the American Chemical Society 1985-11-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthetic Organic Chemical Models for Transmembrane ChannelsGeorge W. Gokel and Oscar MurilloView Author Information Bioorganic Chemistry Program Department of Molecular Biology & Pharmacology, Washington University School Medicine, 660 S. Euclid Avenue, Campus Box 8103, St. Louis, Missouri 63110 Cite this: Acc. Chem. Res. 1996, 29, 9, 425–432Publication Date (Web):September 11, 1996Publication History Received17 April 1996Published online11...

10.1021/ar9601353 article EN Accounts of Chemical Research 1996-09-11

10.1002/anie.197205301 article EN Angewandte Chemie International Edition 1972-06-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSyntheses of calcium-selective, substituted diaza-crown ethers: a novel, one-step formation bibracchial lariat ethers (BiBLES)Vincent J. Gatto and George W. GokelCite this: Am. Chem. Soc. 1984, 106, 26, 8240–8244Publication Date (Print):December 1, 1984Publication History Published online1 May 2002Published inissue 1 December 1984https://pubs.acs.org/doi/10.1021/ja00338a038https://doi.org/10.1021/ja00338a038research-articleACS PublicationsRequest...

10.1021/ja00338a038 article EN Journal of the American Chemical Society 1984-12-01

G. W. Gokel, D. M. Dishong and C. J. Diamond, Chem. Soc., Commun., 1980, 1053 DOI: 10.1039/C39800001053

10.1039/c39800001053 article EN Journal of the Chemical Society Chemical Communications 1980-01-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHost-guest complexation. 11. Survey of chiral recognition amine and amino ester salts by dilocular bisdinaphthyl hostsEvan P. Kyba, Joseph M. Timko, Lester J. Kaplan, Feike De Jong, George W. Gokel, Donald CramCite this: Am. Chem. Soc. 1978, 100, 14, 4555–4568Publication Date (Print):July 1, 1978Publication History Published online1 May 2002Published inissue 1 July...

10.1021/ja00482a040 article EN Journal of the American Chemical Society 1978-07-01
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