A5089200309- Clostridium difficile and Clostridium perfringens research
- Antimicrobial Resistance in Staphylococcus
- Microscopic Colitis
- Infective Endocarditis Diagnosis and Management
- Bacterial Identification and Susceptibility Testing
- Streptococcal Infections and Treatments
- Pneumonia and Respiratory Infections
- Antifungal resistance and susceptibility
- Antibiotic Resistance in Bacteria
- Pneumocystis jirovecii pneumonia detection and treatment
- Antibiotic Use and Resistance
- Fungal Infections and Studies
- Antibiotics Pharmacokinetics and Efficacy
- COVID-19 Clinical Research Studies
- Nosocomial Infections in ICU
- Viral gastroenteritis research and epidemiology
- Respiratory viral infections research
- Sepsis Diagnosis and Treatment
- Mycobacterium research and diagnosis
- Actinomycetales infections and treatment
- Helicobacter pylori-related gastroenterology studies
- Cardiac Valve Diseases and Treatments
- Urinary Tract Infections Management
- Gastrointestinal motility and disorders
- Tuberculosis Research and Epidemiology
Rabin Medical Center
2016-2025
Tel Aviv University
2016-2025
Versus Arthritis
2023
Weatherford College
2023
Infectious Disease Consultants
2021
Arthur M. Sackler Gallery
2021
Schneider Children's Medical Center
2012
Schneider Children's Hospital
2012
Boston Children's Hospital
2012
Clalit Health Services
2008
Treatment options for carbapenem-resistant Enterobacteriaceae (CRE) infections are limited and CRE remain associated with high clinical failure mortality rates, particularly in vulnerable patient populations. A Phase 3, multinational, open-label, randomized controlled trial (TANGO II) was conducted from 2014 to 2017 evaluate the efficacy/safety of meropenem-vaborbactam monotherapy versus best available therapy (BAT) CRE.A total 77 patients confirmed/suspected infection (bacteremia,...
Gram-negative bacteremia is a major cause of morbidity and mortality in hospitalized patients. Data to guide the duration antibiotic therapy are limited.This was randomized, multicenter, open-label, noninferiority trial. Inpatients with gram-negative bacteremia, who were afebrile hemodynamically stable for at least 48 hours, randomized receive 7 days (intervention) or 14 (control) covering therapy. Patients uncontrolled focus infection excluded. The primary outcome 90 composite all-cause...
Patients with cancer undergoing treatment are at high risk of COVID-19 following SARS-CoV-2 infection; however, their ability to produce an adequate antibody response messenger RNA vaccines is unclear.
Recent exposure to azoles is an important risk factor for infection with fluconazole-resistant Candida spp., but little known about the role of antibacterial drug in emergence drug-resistant Candida. We did a prospective nationwide surveillance study candidemia Israel and analyzed propensity score-adjusted association between antifungal bloodstream C. glabrata isolates. Four hundred forty-four episodes (450 isolates, 69 [15%] 38 [8.5%] isolates) from 18 medical centers were included. was...
Colistin has re-entered clinical use by necessity. We aimed to assess its effectiveness and safety compared with newer antibiotics. This was a single-centre, prospective cohort study. Inclusion criteria were microbiologically documented pneumonia, urinary tract infection, surgical site meningitis or bacteraemia treated appropriately colistin versus imipenem, meropenem ampicillin/sulbactam (comparators). All consecutive patients included, only once, between May 2006 July 2009. The primary...
<b>Objective</b> To show non-inferiority of trimethoprim-sulfamethoxazole compared with vancomycin for the treatment severe infections due to meticillin resistant <i>Staphylococcus aureus</i> (MRSA). <b>Design</b> Parallel, open label, randomised controlled trial. <b>Setting</b> Four acute care hospitals in Israel. <b>Participants </b>Adults caused by MRSA susceptible and vancomycin. Patients left sided endocarditis, meningitis, chronic haemodialysis, prolonged neutropenia were excluded....
A new CHROMagar KPC medium was compared to MacConkey agar with carbapenem discs and PCR for the bla(KPC) gene rapid detection of carbapenem-resistant Klebsiella pneumoniae. The sensitivity specificity relative were 100% 98.4%, respectively, 92.7% 95.9%, agar.
Obesity and Clostridium difficile infection (CDI) are both related to an increased Firmicutes/Bacteroidetes ratio in the intestinal microbiota. However, association between obesity CDI is unknown. We aimed assess hospitalized patients.We conducted a retrospective case-control study. From January December 2011, all consecutive patients with CDI, 2 internal medical departments hospitals, were included. Patients compared without diarrhea, during same period departments, matched by age, sex,...
To determine the impact of early surgical intervention on long-term survival in patients with infective endocarditis (IE), charts all who had IE from January 1987 through December 1996 were reviewed. A total 252 definite or possible included. Forty-four (17.5%) surgery median hospital day 2 (range, 0-30 days), and 208 (82.5%) received medical treatment alone. On multivariate analysis, several variables, including intervention, improved rates (hazard ratio, 1.5; P=.03), mainly Staphylococcus...
Abstract: The number of intensive care unit patients with infections caused by multidrug‐resistant organisms is increasing in most developed countries. We report the case a deceased multiorgan donor, who was an asymptomatic carrier carbapenem‐resistant K lebsiella pneumoniae ( CR ‐ KP ) respiratory tract, condition that not diagnosed before organ harvesting and transplantation. outcome 2 kidney recipients, liver recipient, 1 lung recipients uneventful; particular, no evidence infection...
IntroductionRespiratory syncytial virus (RSV) is considered a major pathogen that causes acute influenza-like illness. The objective of this study was to compare the clinical outcomes patients with laboratory-confirmed RSV and influenza infection.MethodsAdults hospitalized in Beilinson Hospital (October 2017–April 2018) or were included. primary outcome composite RSV/influenza complications: 30-day mortality, pneumonia, mechanical ventilation, vasopressor support, intensive care unit...
ObjectivesTo evaluate the efficacy and safety of co-trimoxazole versus that vancomycin in adults with methicillin-resistant Staphylococcus aureus (MRSA) bacteraemia.
The clinical characteristics of internal medicine ward (IMW) patients with candidemia are unclear. aim this study was to define the candidemic IMW and incidence, species distribution, outcomes these compared surgical intensive care unit (ICU) patients.A retrospective cohort in IMWs, general surgery wards, an ICU at Beilinson Hospital during period 2007-2014 analyzed.A total 118 were identified six two one hospital. Candida albicans leading causative agent (41.1%). Higher proportions...