A5081414334- Helminth infection and control
- Neurobiology and Insect Physiology Research
- Parasites and Host Interactions
- Aquaculture Nutrition and Growth
- Crustacean biology and ecology
- Parasite Biology and Host Interactions
- Reproductive biology and impacts on aquatic species
- Coccidia and coccidiosis research
- Seaweed-derived Bioactive Compounds
- Echinoderm biology and ecology
- Sperm and Testicular Function
- Aquatic life and conservation
- Invertebrate Immune Response Mechanisms
- Cephalopods and Marine Biology
- Marine Bivalve and Aquaculture Studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Reproductive Biology and Fertility
- Marine Sponges and Natural Products
- Agricultural safety and regulations
- Insect and Arachnid Ecology and Behavior
- Trace Elements in Health
- Physiological and biochemical adaptations
- Hypothalamic control of reproductive hormones
- Parasitic Infections and Diagnostics
- Autophagy in Disease and Therapy
Mahidol University
2016-2025
Burapha University
2015-2019
Thailand Research Fund
2007
Rockefeller Foundation
1971
Macrobrachium rosenbergii is the most economically important of cultured freshwater crustacean species, yet there currently a deficiency in genomic and transcriptomic information for research requirements. In this study, we present an silico analysis neuropeptide genes within female M. eyestalk, central nervous system, ovary. We could confidently predict 37 preproneuropeptide transcripts, including those that encode bursicons, cardioactive peptide, hyperglycemic hormones, eclosion hormone,...
Parkinson's disease (PD) is associated with dopaminergic neuron loss and alpha-synuclein aggregation caused by ROS overproduction, leading to mitochondrial dysfunction autophagy impairment. Recently, andrographolide (Andro) has been extensively studied for various pharmacological properties, such as anti-diabetic, anti-cancer, anti-inflammatory, anti-atherosclerosis. However, its potential neuroprotective effects on neurotoxin MPP+-induced SH-SY5Y cells, a cellular PD model, remain...
Vitamin A deficiency was induced in young adult male rats by feeding them with a synthetic vitamin-A-deficient diet. The histology of their testes examined periodically from 1 to 20 days following the point where animals ceased gain weight. earliest sign histological change seminiferious tubules, which occurred at day 3, sloughing spermatids and spermatocytes into lumina seminiferous tubules. Pyknotic cells were seen throughout epithelium significant number beginning 4 or 5. Most dead early...
Parkinson's disease (PD) is associated with aggregation of α-synuclein and selective death dopaminergic (DA) neurons in the substantia nigra, thereby leading to cognitive motor impairments. Nowadays, drugs commonly used for PD treatment, such as levodopa, provide only symptomatic relief. Therefore, seeking new against PD, especially from plants marine organisms, one major research areas be explored. This study aimed investigate anti-Parkinson activity extracts sea cucumber, Holothuria...
Our previous studies revealed a mating attractant or possibly pheromone released from molting reproductive mature female prawns, Macrobrachium rosenbergii, stimulates the expression of insulin-like androgenic gland hormones in co-culture system. The is perceived by olfactory receptors with setae located on short lateral antennules (slAn), which connect to neuropil central nervous system (CNS) male prawns. This neural signaling propagating through CNS mediated at least four neuropeptides,...
Abstract The anatomical, histological, and histochemical characteristics of the foregut (FG), midgut (MG), hindgut (HG), as well their alterations during ovarian cycle in female prawns, Macrobrachium rosenbergii , were investigated. esophagus (ESO), cardia (CD), pylorus (PY) are main components FG. An epithelium (Ep) with thick cuticle (Cu) layers lining ESO, ESO is encircled by glands. CD has a musculature, whereas Ep PY characterized numerous villi columnar cells thinner layer Cu. inner...
Abstract Peyer's patches of conventional adult mice are studied with light and electron microscopy. Based on cellular types distribution, each lymphoid follicle patch is divisible into four zones: the germinal center, small lymphocytic, interfollicular subepithelial zones. Three distinct cell present in i.e., dendritic reticular cells; tingible body macrophages; lymphocytes which classifiable large, medium size. The size great majority this zone. lymphocytic zones characterized by a...
Normal chromatin condensation is important for sperm fertilising ability. However, routine semen analysis does not identify defects in structure. This study aimed to investigate the of and DNA integrity spermatozoa infertile men deduce relationship with quality, as measured by conventional parameters. Semen was carried out assess quality according World Health Organization criteria. The remaining aliquot each sample processed transmission electron microscopy, chromomycin A3 (CMA3) terminal...
Parkinson's disease (PD) is a well-known neurodegenerative disorder characterized by dopaminergic (DA) neuron loss and α-synuclein aggregation. Recent study revealed that the extracts from sea cucumber, Holothuroidea spp., exhibited neuroprotective lifespan extension effects in Caenorhabditis elegans model. Interestingly, black Holothuria leucospilota, possesses body wall specialized organ called cuvierian tubules containing high amount of bioactive compounds. In this study, (BW) (CT)...
Abstract The sea cucumber Holothuria scabra is an economically valuable marine species which distributed throughout the Asia–Pacific region. With natural population declining due to over fishing, aquaculture of this deemed necessary. Hence, it essential understand mechanisms regulating reproduction in order increase their populations. Sex steroids, including estrogens, androgens and progestogens, play important role most vertebrates several invertebrates. It has been proposed that cucumbers...
Objective: To investigate the effect of hexane solvent fraction Halymenia durvillei (HDHE) on triple-negative breast cancer. Methods: The phytochemical profile HDHE was investigated by GC-MS. cytotoxicity against MDA-MB-231 cells determined. apoptotic and autophagic effects were analyzed. expression molecular markers controlling apoptosis, autophagy, DNA damage, endoplasmic reticulum (ER) stress Results: contains a mixture fatty acids, mainly hexadecanoic acid. at cytotoxic concentration...