- Molecular Sensors and Ion Detection
- Luminescence and Fluorescent Materials
- Seaweed-derived Bioactive Compounds
- Advanced biosensing and bioanalysis techniques
- Phytochemistry and Biological Activities
- Electrochemical sensors and biosensors
- Genetics, Aging, and Longevity in Model Organisms
- Analytical Chemistry and Sensors
- Electrochemical Analysis and Applications
- Algal biology and biofuel production
- Electrospun Nanofibers in Biomedical Applications
- Natural Compound Pharmacology Studies
- Conducting polymers and applications
- Supramolecular Chemistry and Complexes
- Fatty Acid Research and Health
- Dendrimers and Hyperbranched Polymers
- Echinoderm biology and ecology
- Bioactive Compounds and Antitumor Agents
- Sulfur Compounds in Biology
- Skin Protection and Aging
- Carbon and Quantum Dots Applications
- Metabolomics and Mass Spectrometry Studies
- Synthesis of Organic Compounds
- Polydiacetylene-based materials and applications
- Alzheimer's disease research and treatments
King Mongkut's University of Technology Thonburi
2014-2024
Bangkok University
2015
Chulalongkorn University
2009-2014
University of California, Riverside
2010
A series of bishydrazide compounds have been developed for selective turn-on detection Al3+ cation, based on metal chelation-enhanced fluorescence (CHEF) effects that inhibit the nonradiative PET and ESIPT processes. In aqueous solution, selectively induces strong these with large Stokes shifts up to ∼133 nm emission colors varying from blue orange. solid phase, both Zn2+ give apparent which is simultaneously detected chromatographic separation.
Triphenylamine-based fluorophores containing pyrene or corannulene show variable fluorescence quenching sensitivity toward nitro explosives. The most sensitive fluorophore is capable of detecting TNT on the ng cm(-2) scale; array useful for identifying aromatics.
Optical sensors capable of colorimetric visualization and/or fluorescence detection have shown tremendous potential for field technicians and emergency responders, owing to the portability low cost such devices. Polydiacetylene (PDA)-enhanced nanofibers are particularly promising due high surface area, facile functionalization, simple construction, versatility empower either or signaling. We demonstrate here a dual-mode optical sensing with electrospun embedded various PDAs. The...
Parkinson's disease (PD) is the second most common neurodegenerative which still incurable. Sea cucumber-derived compounds have been reported to be promising candidate drugs for treating age-related neurological disorders. The present study evaluated beneficial effects of Holothuria leucospilota (H. leucospilota)-derived compound 3 isolated from ethyl acetate fraction (HLEA-P3) using Caenorhabditis elegans PD models. HLEA-P3 (1 50 µg/mL) restored viability dopaminergic neurons. Surprisingly,...
Traditionally, lichen has been used for many purposes, but there remains a lack of understanding regarding the chemical composition and antimicrobial characteristics Diorygma pruinosum , native to Vietnam.
A series of water-soluble fluorescent dendritic compounds composed phenylene-ethynylene repeating units and anionic carboxylate or cationic ammonium peripheral groups were synthesized. The first generation dendrimer containing nine six exhibited a highly selective fluorescence quenching by Hg(2+) ions. Stern-Volmer constant (K(sv)) was 33,700 M(-1) in aqueous media the presence Triton X-100 surfactant.
Gold nanoparticles stabilized by thermoresponsive polymer, poly(N-isopropylacrylamide) (PNIPAM-AuNPs) were prepared surface grafting of thiol-terminated PNIPAM onto citrate-stabilized AuNPs. The color change the PNIPAM-AuNPs solution from red to blue-purple without precipitation when was heated 40 °C, above lower critical temperature (LCST) PNIPAM, indicated property synthesized used detect proteins chemical nose approach based on fluorescence quenching fluorophore An array-based sensing...
A novel phenylacetylene derivative (<bold>3</bold>) was successfully synthesized <italic>via</italic> Sonogashira coupling and a Knoevenagel reaction for cyanide ion detection.
Parkinson's disease (PD) is a well-known neurodegenerative disorder characterized by dopaminergic (DA) neuron loss and α-synuclein aggregation. Recent study revealed that the extracts from sea cucumber, Holothuroidea spp., exhibited neuroprotective lifespan extension effects in Caenorhabditis elegans model. Interestingly, black Holothuria leucospilota, possesses body wall specialized organ called cuvierian tubules containing high amount of bioactive compounds. In this study, (BW) (CT)...
Sea cucumbers are marine organism that have long been used for food and traditional medicine in Asian countries. Recently, we shown ethyl acetate fraction (HLEA) of the crude extract black sea cucumber, Holothuria leucospilota, could alleviate Parkinsonism Caenorhabditis elegans PD models. In this study, found effective neuroprotective activity is attributed to HLEA-P1 compound chemically isolated identified H. leucospilota acetate. We reported here attenuate DAergic neurodegeneration,...
Seaweed has attracted attention as a bioactive source for preventing different chronic diseases, including liver injury and non-alcoholic fatty disease, the leading cause of liver-related mortality. Caulerpa lentillifera is characterized tropical edible seaweed, currently being investigated health benefits its extracts substances. This study examined effects C. extract in ethyl acetate fraction (CLEA) on controlling lipid accumulation metabolism HepG2 cells induced with oleic acid through...
Due to an increase in the production of green tea, amount leaf waste has increased enormously, causing serious environmental problems. With regard awareness, possibility reusing leaves tea as a low‐cost and abundantly available source natural dye for dyeing cotton fibres was investigated. Natural powder from (NDPT) successfully applied without mordant by batch experiments. NDPT obtained dark brown with yield 2.7 ± 0.5% w/w dried tea. The optimal conditions onto were: pH solution, 3; material...
This paper reports the fabrication of solid-state nanofiber sensor arrays and their use for detection multiple proteins using principal component analysis (PCA). Four cationic anionic fluorescently embedded nanofibers are generated by an electrospinning method, yielding unique patterns fluorescence change upon interaction with protein samples. Five metal nonmetal containing proteins, i.e., hemoglobin, myoglobin, cytochrome c, BSA, avidin, have been investigated; results show that distinct...
Obesity is a multifactorial disease characterized by an excessive accumulation of fat, which in turn poses significant risk to health. Bioactive compounds obtained from macroalgae have demonstrated their efficacy combating obesity various animal models. The green Caulerpa lentillifera (CL) contains numerous active constituents. Hence, the present study, we aimed elucidate beneficial anti-obesity effects extracts derived C. using Caenorhabditis elegans model. ethanol (CLET) and ethyl acetate...
The compound<bold>2</bold>mixed α-cyclodextrin exhibits the highest CN<sup>−</sup>recognition sensitivity in aqueous media with detection limit of 1.3 μM. Test strips based on compound<bold>2</bold>can act as a convenient and efficient CN<sup>−</sup>test kit.