A5017622681- Aquaculture disease management and microbiota
- Aquaculture Nutrition and Growth
- Reproductive biology and impacts on aquatic species
- Invertebrate Immune Response Mechanisms
- Animal Virus Infections Studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Antimicrobial Peptides and Activities
- interferon and immune responses
- Sperm and Testicular Function
- Reproductive System and Pregnancy
- Environmental Toxicology and Ecotoxicology
- RNA Interference and Gene Delivery
- Microplastics and Plastic Pollution
- Immune Response and Inflammation
- Fish Biology and Ecology Studies
- Immune Cell Function and Interaction
- Marine Biology and Environmental Chemistry
- Virology and Viral Diseases
- Animal Genetics and Reproduction
- Aquatic life and conservation
- Mosquito-borne diseases and control
- Algal biology and biofuel production
- Identification and Quantification in Food
- Estrogen and related hormone effects
- Marine Bivalve and Aquaculture Studies
Instituto Español de Oceanografía
2016-2025
Centro Oceanográfico de Murcia
2020-2024
Consejo Superior de Investigaciones Científicas
2022-2023
Universidad de Murcia
2000-2015
Utrecht University
2012
Centro de Investigación en Sanidad Animal
2009-2010
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria
2009
Aquaculture is an extremely prosperous market threatened by pathogen outbreaks, including viruses as nodavirus (NNV), which infect fish species with special interest in trading such European sea bass. Antimicrobial peptides (AMPs) might constitute potential antiviral agents, had been previously evaluated positive prospects, based on their properties immunomodulators or directly killing pathogens. In this line, we aimed to evaluate dual role administering two bass synthetic AMPs (Hamp Dic)...
The gilthead seabream is a protandrous hermaphrodite seasonal breeding teleost with bisexual gonad that offers an interesting model for studying the testicular regression process occurs in both involution and sex change. Insofar as fish reproduction concerned, little known about cell renewal elimination during reproductive cycle of teleosts asynchronous spermatogenesis. We have previously described how acidophilic granulocytes infiltrate testis postspawning where, surprisingly, they produce...
One of the most powerful innate immune responses against viruses is mediated by type I IFN. In teleost fish, it known that virus infection triggers expression ifn and many IFN-stimulated genes, but viral RNA sensors mediators leading to IFN production are scarcely known. Thus, we have searched for presence these genes in gilt-head sea bream (Sparus aurata) European bass (Dicentrarchus labrax), evaluated their after with nervous necrosis (VNNV) brain, main target tissue, gonad, used transmit...
Viruses are threatening pathogens for fish aquaculture. Some of them transmitted through gonad fluids or gametes as occurs with nervous necrosis virus (NNV). In order to be the gonad, should colonize and replicate inside some cell types this tissue avoid subsequent immune response locally. However, whether NNV colonizes that infected, how in is regulated has never been studied. We have demonstrated first time presence localization into testis after an experimental infection European sea bass...
Abstract Nervous necrosis virus (NNV) is the etiological agent of viral encephalopathy and retinopathy in many fish species, including European sea bass ( Dicentrachus labrax ) great economic losses to farmers. To solve this problem production, antimicrobial peptides (AMPs) have been identified as potential candidates for NNV treatment aquaculture. Hepcidin (Hamp) one most promising AMPs. Thus, we aimed evaluate therapeutic application Hamp synthetic peptide after challenge. was able...
The testis is a tightly controlled dynamic tissue. In mammals, there growing evidence that estrogen plays role in the regulation of testicular functions. teleosts, high levels 17beta-estradiol (E2) serum correlate with end spermatogenesis, spawning, and initiation postspawning stages when spermatogonia are main cell types testis. Moreover, E2 modulates leukocyte functions several teleost species. We hypothesized, therefore, would induce infiltration acidophilic granulocytes cause resumption...
Abstract Background Leukocytes are found within the testis of most, if not all, mammals and involved in immunological surveillance, physiological regulation tissue remodelling. The seasonal breeding fish undergoes a regression process. In present study, second reproductive cycle (RC) protandrous teleost fish, gilthead seabream, was investigated presence leukocytes analysed. Special attention has been paid to testicular degenerative process which is particularly active last stage RC probably...