- Liver Disease Diagnosis and Treatment
- Chemotherapy-induced organ toxicity mitigation
- Antibiotic Resistance in Bacteria
- Advanced Computing and Algorithms
- Antibiotic Use and Resistance
- Pregnancy and Medication Impact
- Hepatitis B Virus Studies
- Sperm and Testicular Function
- Photonic and Optical Devices
- Nitric Oxide and Endothelin Effects
- Advanced Fluorescence Microscopy Techniques
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Reproductive Biology and Fertility
- Hepatitis C virus research
- Sesame and Sesamin Research
- Selenium in Biological Systems
- Antibiotics Pharmacokinetics and Efficacy
- Reproductive System and Pregnancy
- Ovarian function and disorders
- Optical Coherence Tomography Applications
- Mesenchymal stem cell research
- Erythrocyte Function and Pathophysiology
- Diabetes, Cardiovascular Risks, and Lipoproteins
Jouf University
2019-2024
Background: the nephrotoxicity of methotrexate (MTX) is observed in high-dose therapy. Moreover, low-dose MTX therapy for rheumatic diseases debatable and claimed to cause renal impairment. This study aimed at studying effect repeated low doses on rat kidneys assessing efficacy adipose-derived mesenchymal stem cells (AD-MSCs) platelet rich plasma (PRP) attenuating this effect. Methods: Forty-two male Wistar rats were used, 10 donors AD-MSCs PRP, 8 served as control, remaining subjected...
Intensive care units are complex environments favoring high resistance in microorganisms. This study evaluated the and distribution dynamics of resistant Gram-negative bacteria (GNB) patients admitted to intensive units. retrospective, record-based, cross-sectional analyzed all antibiograms ICUs. The BD Phoenix system (BD Diagnostics, Sparks, MD, USA) was used for bacterial identification antimicrobial testing. Clinical Laboratory Standard Institute recommendations were Frequencies...
Background: Peroxynitrite (ONOO−) is an oxidant linked with several human pathologies. Apigenin, a natural flavonoid known for its health benefits, remains unexplored in relation to ONOO− effects. This study investigated the potential of apigenin structurally protect fibrinogen, essential blood clotting factor, from ONOO−-induced damage. Methods: Multi-approach analyses were carried out where fibrinogen was exposed generation while testing efficacy apigenin. The role against modifications...
The aim of this study was to investigate the possible protective effect antioxidant sodium selenite (0.1 mg/kg/day) via gavage once a day for 30 days first time in model malathion (27 induced testicular toxicity mice. Results revealed that concomitant administration selenium has prevented decrease mean final and relative body weight as well compared group. Concomitant also decreased malondialdehyde contents increased serum levels follicle stimulating hormone, luteinizing testosterone,...