A5053487386- Porphyrin and Phthalocyanine Chemistry
- Photodynamic Therapy Research Studies
- Nanoplatforms for cancer theranostics
- Selenium in Biological Systems
- Animal Disease Management and Epidemiology
- Plant Micronutrient Interactions and Effects
- Trace Elements in Health
- Luminescence and Fluorescent Materials
- Carcinogens and Genotoxicity Assessment
- Photochromic and Fluorescence Chemistry
- Nanoparticles: synthesis and applications
- Sperm and Testicular Function
- Demographic Trends and Gender Preferences
- Advanced biosensing and bioanalysis techniques
- Inflammatory mediators and NSAID effects
- Viral Infections and Vectors
- Enzyme function and inhibition
- Cholinesterase and Neurodegenerative Diseases
- Natural Products and Biological Research
- Synthesis and biological activity
- Medical Device Sterilization and Disinfection
- Influenza Virus Research Studies
- Aluminum toxicity and tolerance in plants and animals
- Ultrasound and Cavitation Phenomena
- Livestock Management and Performance Improvement
Karadeniz Technical University
2017-2025
Imperial College London
2025
Ankara University
1999-2019
Anadolu University
2018
Columbia University Irving Medical Center
2017
Dicle University
2015
This study critically evaluates the biocompatibility and toxicological safety of EverX Posterior (eXP) Filtek Ultimate (FU) dental composites following International Standardization Organization (ISO) 10993-17:2023 10993-18:2020 guidelines. Our research highlights important findings on depth cure, water absorption, solubility, release profiles organic compounds in these using advanced chromatographic techniques. The analysis revealed that both eXP FU are safe for patients regarding...
Focused ultrasound in combination with intravenously injected microbubbles offers a non-invasive and localised method to deliver drugs across the blood-brain barrier, enabling targeted treatment of brain disorders. Recently, we have shown that applying sequences Rapid Short-Pulses (RaSP; 5 μs pulses emitted at 1.25 kHz grouped into 10 ms bursts) can an improved efficacy safety profile compared traditionally-used longer (> ms). In this study, examined extent which RaSP allowed extravasation...
In this work, the phytochemical profile of Cardamine raphanifolia subsp. acris extracts was analyzed, and total phenolic/flavonoid content were evaluated using spectrophotometric methods. The highest phenolic found in buthanol (ButE), while flavonoid detected chloroform (ChrE). GC‐MS analysis identified 32 compounds such as n‐hexadecanoic acid ethyl acetate (EtcE). antioxidant activities confirmed through 2,2‐diphenyl‐1‐picrylhydrazyl radical (DPPH) ferric reducing power (FRAP) assays, but...
Propolis is a resinous bee product, rich of polyphenolic compounds and flavonoids. It known that in different geographic zones its chemical composition varies due to the plant sources. Many biological properties including antimicrobial, antioxidative, anti-inflammatory, antitumoral, antigenotoxic, antimutagenic, cytostatic activities have been ascribed propolis. These effects are predominantly attributed content polyphenols. In this study, we aimed evaluate radioprotective effect ethanolic...
In this work, 3‐({6‐[3‐(dimethylamino)phenoxy]hexyl}oxy)phthalonitrile ( 2 ) and the target zinc (II) phthalocyanine 3 its ammonium derivative 3a are synthesized, phototoxic effects of were examined using different methods on A549 lung cancer cells. Then, toll‐like receptor (TLR) signaling pathway was to determine cell death mechanism in The results showed that did not have noticeable cytotoxic actions cells at used concentrations. However, compound markedly reduced viability when irradiated...
In this study, novel silicon(iv) phthalocyanines axially disubstituted with bis[(4-{3-[3-(dimethylamino)phenoxy]propoxy}phenyl)methoxy] and bis[(4-{3-[3-(diethylamino)phenoxy]propoxy}phenyl)methoxy] groups their quaternized derivatives were synthesized characterized. Then, supercoiled pBR322 plasmid DNA cleavage properties investigated using agarose gel electrophoresis. The in vitro PDT effects of Si-3a Si-4a the MTT cell viability assay against HCT-116, A549 SH-SY5Y lines. did not show upon...
A series of novel polyhalogenated 2-phenylbenzimidazoles have been synthesized and evaluated for in vitro antistaphylococcal activity against drug-resistant bacterial strains (methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium. Certain compounds inhibit growth perfectly. 11 was active than vancomycin (0.78 μg/mL) with the lowest MIC values 0.19 μg/mL methicillin-resistant 8 35 exhibited best inhibitory faecium (1.56 μg/mL). The mechanism action this class...
In this work, peripheral or nonperipheral tetra‐[4‐(9 H ‐carbazol‐9‐yl)phenoxy] substituted cobalt(II), manganese (III) phthalocyanines were synthesized for the first time. Their acetylcholinesterase from Electrophorus electricus (AChE), butyrylcholinesterase equine serum (BuChE), and α‐glucosidase Saccharomyces cerevisiae inhibition investigated spectrophotometrically. Finally, in vitro cytotoxicities of compounds on human neuroblastoma (SH‐SY5Y) cell line using MTT viability assay. The...