- Olfactory and Sensory Function Studies
- Biochemical Analysis and Sensing Techniques
- Advanced Chemical Sensor Technologies
- Allergic Rhinitis and Sensitization
- Surgical Simulation and Training
- Neurobiology and Insect Physiology Research
- Head and Neck Cancer Studies
- Obstructive Sleep Apnea Research
- Asthma and respiratory diseases
- Augmented Reality Applications
- Respiratory and Cough-Related Research
- Sinusitis and nasal conditions
- Teleoperation and Haptic Systems
- Cancer Diagnosis and Treatment
- Ear Surgery and Otitis Media
- Adenosine and Purinergic Signaling
- Biochemical effects in animals
- Voice and Speech Disorders
- Cancer Immunotherapy and Biomarkers
- Color perception and design
- Peptidase Inhibition and Analysis
- Peripheral Neuropathies and Disorders
- Anatomy and Medical Technology
- Brain Metastases and Treatment
- Virtual Reality Applications and Impacts
TU Dresden
2016-2020
Philipps University of Marburg
2016-2019
Universitätsklinikum Gießen und Marburg
2016-2019
Taste and Smell Clinic
2019
Justus-Liebig-Universität Gießen
2016-2018
This study investigated the relation of fungiform taste papillae density and saliva composition with perception patients suffering from diagnosed disorders. For this purpose, 81 40 healthy subjects were included. Taste was measured by means regional whole mouth chemosensory tests, electrogustometry. Olfaction assessed using Sniffin Sticks. Fungiform quantified "Denver Papillae Protocol for Objective Analysis Papillae". In addition, salivary parameters [flow rate, total proteins, catalase,...
Background Viral rhinitis (the “common” cold) is a frequent worldwide disease. Olfactory dysfunction one complication that arises during infection, which in most cases heals up spontaneously upon recovery, whereas some it may persist as partial or total loss of olfaction. The aim this prospective study was to investigate the change other chemosensory systems cold. Methods Fifty‐eight patients (age 18 69 years) with an acute cold were compared healthy control group (n = 59; age 19 63 years)....
Aim of the current work was to examine developmental changes in adolescents' olfactory performance and personal significance olfaction. In first study identification abilities 76 participants (31 males 45 females aged between 10 18 years; M = 13.8, SD 2.3) evaluated with Sniffin Stick test, presented a cued an uncued manner. Verbal fluency additionally examined for control purpose. second 131 (46 85 (M 14.4, 2.2) filled importance olfaction questionnaire. Odor increased significantly age...
The prevalence and activity of regulatory T cells in patients with cancer correlates poor prognosis. These are characterized by their expression Forkhead box protein-3 (Foxp3). Squamous cell carcinoma is the most prevalent type head neck region overall survival rates, also due to early spread metastatic cells.Primary tumor specimens as well lymph node harvested during dissection 65 a diagnosis HNSCC were subjected immunohistochemical H-score analysis Foxp3 expression. Demographics,...
Introduction: CD39 is the rate-limiting enzyme in generation of immunosuppressive adenosine and its expression activity are significant tumor progression. Squamous cell carcinoma head neck (HNSCC) shows an overall poor prognosis due to high local recurrence rates early metastatic spread.Material methods: Primary specimens lymph node harvested during dissection 65 patients with a diagnosis HNSCC were subjected immunohistochemical H-score analysis expression. Demographics, histopathology...
For imaging of bony structures, especially for the anterior and lateral skull base in ORL medicine, cone beam computed tomography (CBCT) is an increasingly used alternative to CT, with a lower exposition plain radiography that makes its use imaging, particularly children, very interesting. The aim this study was analyse possible indications settings CBCT children compare them those adults. A total 554 patients (age range 0-18 years, mean age 10.36 years), who underwent between...
Objectives Olfaction is frequently impaired in chronic rhinosinusitis with nasal polyps (CRSwNP) and often improves after endoscopic sinus surgery (ESS). Data about dynamics of olfactory changes ESS are lacking, little information available concerning whether preoperatively administered glucocorticosteroids predict postoperative olfaction. Therefore, the aim this study was to examine olfaction relation effect preoperative administration CRSwNP. Methods This prospective included 52 CRSwNP...
Objectives/Hypothesis Olfactory dysfunction is common among the general population, with chronic rhinosinusitis (CRS) as one of leading causes. Patients affected by CRS often report changes in taste sensations; however, quantitative measurements have not been performed to date. Therefore, present study aimed investigate gustatory and olfactory function patients prior after multimodal treatment. Study Design Prospective cohort study. Methods Twenty‐one suffering from nasal polyps (14 male,...
The increasing use of minimally invasive techniques such as robotic-assisted devices raises the question how to acquire robotic surgery skills. da Vinci Skills Simulator has been demonstrated be an effective training tool in previous reports. To date, little data are available on proficiency through simulator training. We investigated outcome a structured programme for surgical skills by novices.This prospective study was conducted from January December 2013 using Simulator. Twenty...
Cochlear implantation (CI), the standard therapy for rehabilitation of severe to profound sensorineural hearing loss, exhibits taste dysfunction as a possible postoperative complication. This study aimed investigate changes in and addition baseline function CI candidates.We included 61 patients (32 male, 29 female) planned undergo surgery 23 healthy controls (8 15 female). Gustatory was measured using chemosensory quasi-threshold test (taste strips) electrogustometry (EGM). To exclude...
Sniffin' Sticks have become a popular procedure to measure overall olfactory functionality with 3 subtest: phenyl ethyl alcohol threshold test (T), discrimination (D), and identification (I). However, several procedural components specified by the original paper not been tested nor has impact of deviations measured. The aim present work was performance under modified testing procedures. First, reverse order subtests (IDT) compared more standard practices (TDI). Next, possible background...
The aim of this study was to compare QoL oropharyngeal cancer survivors who had received different treatments.We contacted 954 survivors. Each survivor the questionnaires EORTC QLQ-C30 and QLQ-H&N35.A total 263 completed (28% responses). Forty-five them undergone surgery, 20 definitive radiotherapy or chemo-radiotherapy, 85 surgery plus adjuvant radiotherapy, 111 chemo-radiotherapy. Survivors reported significantly more problems with swallowing (B=13.43 [95% Confidence Interval (CI)...
The aim of this study was to evaluate the effect (1) addition trigeminal stimuli an olfactory stimulus and (2) congruence in odorous mixture after repeated odor presentation. Twenty-five normosmic volunteers were enrolled presented stimulation blocks, consisting three habituation (H) (orange odor), one dishabituation (DH) (control condition, orange odor; congruent + CO2; incongruent l-isopulegol), dishabituated (D) odor). Olfactory event-related potentials analyzed. Response amplitudes...
<b>Einleitung</b> Im Jahr 2006 wurde eine interdisziplinäre Stellungnahme zur präoperativen Gerinnungsdiagnostik bei Kindern vor einer Tonsillektomie/Adenotomie (TE/AT) veröffentlicht. Diese empfiehlt, auf die präoperative "Routinegerinnung" zu verzichten und stattdessen einen standardisierten Fragebogen Abklärung Blutungsneigung verwenden. Ziel der vorliegenden Studie war es überprüfen, ob nach Umsetzung Empfehlung Veränderung Nachblutungsrate gekommen ist. <b>Methoden</b> Mittels...
Zusammenfassung Chronischer Husten wird bisher größtenteils über rein subjektive Mittel erfasst und beurteilt – zum Beispiel mithilfe von Fragebögen und/oder Tagebüchern. Die Beurteilung stimmt jedoch oft nicht mit den objektiven Messdaten überein. Bei Patienten chronischem sollte daher die Basisdiagnostik Verlaufskontrolle jedweder medikamentösen Therapie einer Kombination aus subjektiven Kriterien unterzogen werden.
Background: Numerous diseases are mediated by autoimmune mechanisms some of which have been shown to be associated with reduced olfactory function, e.g.systemic lupus erythematosus, Sjögren syndrome, psoriasis vulgaris.Postinfectious smell loss is a frequent cause dysfunction.However, its nature not fully understood, but connections immune processes might possible.The primary aim the present study was therefore investigate possible relation postinfectious processes.Methods: Fifty-two...
Approximately 5 % of the general population is affected by functional anosmia. An additional 15 exhibit decreased olfactory function. Many these individuals ask ENT-doctors or neurologists for help. A cornerstone counselling process assessment The aim this work to give a differentiated overview about administration commonly used psychophysical tests and gustatory function including their normative data. use standardized, reliable validated tools mandatory provide patients with state-of...