Mehmet Özsöz

ORCID: 0000-0003-4037-3445
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Advanced biosensing and bioanalysis techniques
  • Electrochemical Analysis and Applications
  • Electrochemical sensors and biosensors
  • Biosensors and Analytical Detection
  • DNA and Nucleic Acid Chemistry
  • Analytical Chemistry and Sensors
  • CRISPR and Genetic Engineering
  • COVID-19 diagnosis using AI
  • RNA Interference and Gene Delivery
  • RNA and protein synthesis mechanisms
  • SARS-CoV-2 detection and testing
  • Conducting polymers and applications
  • Molecular Junctions and Nanostructures
  • bioluminescence and chemiluminescence research
  • MicroRNA in disease regulation
  • Advanced Chemical Sensor Technologies
  • Metal complexes synthesis and properties
  • Identification and Quantification in Food
  • Radiomics and Machine Learning in Medical Imaging
  • AI in cancer detection
  • Nanopore and Nanochannel Transport Studies
  • Microfluidic and Capillary Electrophoresis Applications
  • Molecular Sensors and Ion Detection
  • Digital Imaging for Blood Diseases
  • Advanced Biosensing Techniques and Applications

Near East University
2018-2024

Mersin Üniversitesi
2021-2024

Padjadjaran University
2024

Universiti Sains Malaysia
2008-2023

South Valley University
2021

University of Lübeck
2021

Cyprus International University
2020

Ege University
2007-2017

Girne American University
2017

North Dakota State University
2017

The outbreak of the novel corona virus disease (COVID-19) in December 2019 has led to global crisis around world. was declared pandemic by World Health Organization (WHO) on 11th March 2020. Currently, affected more than 200 countries with 37 million confirmed cases and 1 death tolls as 10 October Reverse-transcription polymerase chain reaction (RT-PCR) is standard method for detection COVID-19 disease, but it many challenges such false positives, low sensitivity, expensive, requires experts...

10.1007/s12559-020-09787-5 article EN public-domain Cognitive Computation 2021-01-04

Abstract Biomarkers are described as characteristics that provide information about biological conditions whether normal or pathological. Detection of biomarkers at the earliest stage cancer is utmost importance for clinical diagnosis. Electrochemical biosensors allow detecting low levels specific analytes in blood, urine saliva and providing a sensitive approach direct measurement biomarker detection. Moreover, integration electrochemical devices with nanomaterials, such carbon nanotubes,...

10.1002/elan.201501174 article EN Electroanalysis 2016-02-12

Summary A quick, simple, environmentally friendly and cost‐effective screening approach for identifying parameters of adulteration in cold‐pressed olive oil (CPOO) was developed. The technique focused on the electrochemical examination peak alpha‐tocopherol oxidation pencil graphite electrode (PGE). Rapeseed (RO), sunflower (SO), corn (CO) were added to local CPOO varying amounts, mixtures then tested by differential pulse voltammetry (DPV) PGE. Voltammetric analysis its artificially created...

10.1111/ijfs.16931 article EN cc-by International Journal of Food Science & Technology 2024-01-18

Electrochemical genosensors for the detection of Factor V Leiden mutation from polymerase chain reaction (PCR) amplicons using oxidation signal colloidal gold (Au) is described. A pencil graphite electrode (PGE) modified with target DNA, when hybridized complementary probes conjugated to Au nanoparticles, responded appearance a oxide wave at ∼+1.20 V. Specific were immobilized onto nanoparticles in two different modes: (a) Inosine-substituted covalently attached their amino groups 5' end...

10.1021/ac026212r article EN Analytical Chemistry 2003-04-03

The world of drug designing is ever changing. investigations drug-DNA interactions would provide new compounds to be tested for an effect on a biochemical target, and also used as promising hybridization indicators the design DNA biosensors, which will further become microchip systems. An overview reported here about biosensors based primarily drugs interacting with shows how determine this interaction electrochemically, quantification and/or DNA, applications these indicator....

10.1002/1521-4109(200208)14:14<965::aid-elan965>3.0.co;2-u article EN Electroanalysis 2002-08-01

An electrochemical nucleic acid (NA)-based biosensor is a that integrates as the biological recognition element and an electrode signal transducer. The present report provides concepts, terms, methodology related to biorecognition elements, detection principles, type of interactions be addressed, construction performance NA biosensors, including their critical evaluation, which should valuable for wide audience, from academic, biomedical, environmental, food-testing, drug-developing, etc....

10.1351/pac-rep-09-08-16 article EN Pure and Applied Chemistry 2010-04-20

The interaction of double stranded DNA (dsDNA) and single (ssDNA) with Ru(II) complex 2,2′-bipyridine ligand (Ru(bpy)3]2+) methylene blue (MB) were explored by using voltammetric spectrophotometric methods. electrochemistry [Ru(bpy)3]2+ MB was also investigated at a dsDNA-modified carbon paste electrode (CPE), ssDNA-modified CPE bare means differential pulse voltammetry (DPV), cyclic (CV) the increased peak currents observed, in respect to order electrodes. structure determined magnitudes...

10.1002/1521-4109(200103)13:3<219::aid-elan219>3.0.co;2-7 article EN Electroanalysis 2001-03-01

It is explored that methylene blue interacts with the guanine bases specifically, rather than of ss-DNA in general. This interaction can be used as a method quantifying amount oligonucleotide immobilized onto an electrode surface.

10.1002/1521-4109(200210)14:18<1299::aid-elan1299>3.0.co;2-y article EN Electroanalysis 2002-10-01

Phenolic compounds contain classes of flavonoids and non-flavonoids, which occur naturally as secondary metabolites in plants. These compounds, when consumed food substances, improve human health because their antioxidant properties against oxidative damage diseases. In this study, an electrochemical sensor was developed using a carbon paste electrode (CPE) modified with Fe3O4 nanoparticles (MCPE) for the electrosensitive determination sinapic acid, syringic rutin. The characterization...

10.3390/mi12030312 article EN cc-by Micromachines 2021-03-17

10.1016/s0003-2670(01)00942-4 article EN Analytica Chimica Acta 2001-06-01

A quartz crystal microbalance DNA hybridization biosensor, based on thiol-derivatized peptide nucleic acid (PNA) probes, offers unusual in situ differentiation of single-base mismatches. large excess a mismatch oligonucleotide has no effect the frequency response target. Such remarkable distinction between perfect matches and mismatches is illustrated by detection common mutation p53 gene. The greater specificity new mass-sensitive indicatorless device over those analogous PNA-based carbon...

10.1021/ac9706077 article EN Analytical Chemistry 1997-12-01

Small RNA (19-23 nucleotides) molecules play an important role in gene regulation, embryonic differentiation, hematopoiesis, and a variety of cancers. Here, we present ultrasensitive, extremely specific, label-free, rapid electronic detection microRNAs (miRNAs) using carbon nanotubes field-effect transistor functionalized with the Carnation Italian ringspot virus p19 protein biosensor. miRNA-122a was chosen as target, which first hybridized to probe molecule. The probe-miRNA duplex then...

10.1021/ac4018346 article EN Analytical Chemistry 2013-08-02

Abstract In this study graphite electrodes modified by a thin DNA‐imprinted polypyrrole layer, which was able to bind specific target‐DNA, are reported. For aim, electrochemical synthesis of performed on pencil electrode cyclic voltammetry (CV) or potential pulse sequences (PPS). The surface used for determination target‐DNA differential voltammetry. According our best knowledge is first report the application polymer target‐DNA. results showed that molecularly imprinted (MIPPy) layer formed...

10.1002/elan.201300063 article EN Electroanalysis 2013-03-19
Coming Soon ...