- Electrochemical sensors and biosensors
- Electrochemical Analysis and Applications
- Advanced biosensing and bioanalysis techniques
- Analytical Chemistry and Sensors
- Conducting polymers and applications
- DNA and Nucleic Acid Chemistry
- Biosensors and Analytical Detection
- Molecular Junctions and Nanostructures
- Microfluidic and Capillary Electrophoresis Applications
- RNA and protein synthesis mechanisms
- RNA Interference and Gene Delivery
- MicroRNA in disease regulation
- Advanced Nanomaterials in Catalysis
- Analytical Chemistry and Chromatography
- Advanced Chemical Sensor Technologies
- Nanopore and Nanochannel Transport Studies
- Biochemical Analysis and Sensing Techniques
- Graphene research and applications
- Analytical Methods in Pharmaceuticals
- Carbon Nanotubes in Composites
- Analytical chemistry methods development
- Gold and Silver Nanoparticles Synthesis and Applications
- Graphene and Nanomaterials Applications
- Biotin and Related Studies
- SARS-CoV-2 detection and testing
Consejo Nacional de Investigaciones Científicas y Técnicas
2015-2025
Universidad Nacional de Córdoba
2016-2025
University of Central Florida
2025
University of Andorra
2023
University of Verona
2023
Hospital Universitari Germans Trias i Pujol
2023
Hospital Universitario de Fuenlabrada
2023
Guyra Paraguay
2022
Universidad Nacional de Asunción
2018
Instituto de Investigaciones en Ciencias de la Salud
2015-2017
Surface-attached peptide nucleic acids (PNA) are shown to retain their unique and efficient hybridization properties, reported in solution studies. PNA recognition layers thus offer significant advantages for sequence-specific DNA biosensors, compared counterparts. These include significantly higher sensitivity specificity (including greater discrimination against single-base mismatches), faster at room elevated temperatures, minimal dependence on ionic strength, use of shorter (10−15-mer)...
An electrochemical biosensor for the detection of short DNA sequences related to human immunodeficiency virus type 1 (HIV-1) is described. The sensor relies on immobilization and hybridization 21- or 42-mer single-stranded oligonucleotide from HIV-1 U5 long terminal repeat (LTR) sequence at carbon paste strip electrodes. extent between complementary determined by enhancement chronopotentiometric peak Co(phen)3(3+) indicator. Numerous factors affecting probe immobilization, target...
Abstract The performance of enzymatic biosensors based on the immobilization different enzymes within a carbon nanotubes paste electrode (CNTPE) prepared by dispersion multi‐wall (MWNT) and mineral oil is reported in this work. strong electrocatalytic activity towards reduction hydrogen peroxide quinones oxidation NADH have allowed an effective low‐potential amperometric determination lactate, phenols, catechols ethanol, connection with incorporation lactate oxidase, polyphenol oxidase...
A double-stranded (ds) DNA-coated carbon paste electrode is employed as a remarkably sensitive biosensor for the detection of hydrazine compounds. The sensor relies on monitoring changes in intrinsic anodic response surface-confined DNA resulting from its interaction with compounds and requires no label or indicator. Short reaction times (1−10 min) are sufficient part-per-billion levels different hydrazines. Applicability to untreated natural water samples illustrated. mechanism discussed,...
A new electrochemical biosensing strategy has been developed for trace measurements of toxic aromatic amine compounds. The device relies on the intercalative collection amines onto immobilized dsDNA layer followed by potentiometric stripping quantitation accumulated species. enhanced sensitivity, accrued from DNA process, is coupled to selectivity dimensions provided structural requirements such binding. extent and rate accumulation are strongly dependent upon structure Having amino...
We report the first optical biosensor for novel and important cardiac biomarker, galectin-3 (Gal3), using anti-Gal3 antibody as a biorecognition element surface plasmon resonance (SPR) transducing bioaffinity event. The immunosensing platform was built at thiolated Au modified by self-assembling four bilayers of poly(diallyldimethylammonium chloride) graphene oxide (GO), followed covalent attachment 3-aminephenylboronic acid (3ABA). importance GO, both anchoring point field enhancer...
Abstract In this work we summarize the recent activities of our group regarding analytical performance a new composite material, so‐called carbon nanotubes paste electrode (CNTPE) obtained by dispersion multiwall in mineral oil. The electrocatalytic properties towards different redox systems, especially those involved important enzymatic reactions are discussed. Significant shifting overpotentials for oxidation and/or reduction hydrogen peroxide, NADH, phenol, catechol, dopamine, ascorbic...