Danchun Zhang

ORCID: 0000-0003-4045-0682
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Research Areas
  • Genomics and Phylogenetic Studies
  • Ginger and Zingiberaceae research
  • Traditional Chinese Medicine Analysis
  • Plant and Fungal Species Descriptions
  • Plant biochemistry and biosynthesis
  • Viral Infectious Diseases and Gene Expression in Insects
  • Genetic diversity and population structure
  • Essential Oils and Antimicrobial Activity
  • Chromatography in Natural Products
  • Phytochemistry and biological activity of medicinal plants
  • CRISPR and Genetic Engineering
  • Phytochemicals and Antioxidant Activities
  • Biological and pharmacological studies of plants
  • Plant and Fungal Interactions Research
  • Identification and Quantification in Food
  • Sesquiterpenes and Asteraceae Studies
  • Wood and Agarwood Research
  • Plant Diversity and Evolution
  • Tea Polyphenols and Effects
  • Natural product bioactivities and synthesis
  • Nephrotoxicity and Medicinal Plants

Guangzhou University of Chinese Medicine
2021-2025

Guangdong Provincial Hospital of Traditional Chinese Medicine
2021-2024

National Medical Products Administration
2021

China Medical University
2020

Chloroplast genomes for 3 Bidens plants endemic to China (Bidens bipinnata Linn., pilosa and alba var. radiata) have been sequenced, assembled annotated in this study distinguish their molecular characterization phylogenetic relationships. The chloroplast are typical quadripartite structure with two inverted repeat regions separating a large single copy region small region, ranged from 151,599 154,478 bp length. Similar number of SSRs long repeats were found Bidens, wherein mononucleotide...

10.1186/s12864-023-09195-7 article EN cc-by BMC Genomics 2023-03-14

Species in genus Amomum always have important medicinal and economic values. Classification of using morphological characters has long been a challenge because they exhibit high similarity. The main goals this study were to mine genetic markers from cp genomes for species identification discover their evolutionary history through comparative analysis.Three villosum, maximum longipetiolatum sequenced annotated the complete chloroplast (cp) genomes, A. first reported. Three exhibited typical...

10.1186/s12870-022-03898-x article EN cc-by BMC Plant Biology 2022-11-09

ADHs are key genes that catalyze the interconversion between alcohols and aldehydes, which play crucial roles in plant adaptation to a range of abiotic stresses. However, characterization evolutionary pathways ADH antimalarial Artemisia annua still unclear. This study identified 49 A. conducted detailed analysis their structural features, conserved motifs, duplication types, revealing tandem dispersed duplications primary mechanisms gene expansion. Evolutionary ( AanADH ) argyi AarADH...

10.3389/fpls.2025.1533225 article EN cc-by Frontiers in Plant Science 2025-03-19

Artemisia annua L. is the main source of artemisinin, an antimalarial drug. High diversity morphological characteristics and artemisinin contents A. has affected stable production while efficient discrimination method strains not available. The complete chloroplast (cp) genomes 38 were assembled analyzed in this study. Phylogenetic analysis species showed that distinct intraspecific divergence occurred strains. A total divided into two lineages, one lineage containing widely-distributed...

10.3389/fphar.2024.1466578 article EN cc-by Frontiers in Pharmacology 2024-08-14

Generally, chloroplast genomes of angiosperms are always highly conserved but carry a certain number variation among species. In this study, 13 species from Datureae tribe that importance both in ornamental gardening and medicinal usage were studied. addition, seven together with two Solanaceae retrieved the National Center for Biotechnology Information (NCBI) integrated into study. The ranged size 154,686 to 155,979 155,497 155,919 bp Datura Brugmansia, respectively. As total 128 132 genes...

10.3389/fpls.2023.1270052 article EN cc-by Frontiers in Plant Science 2023-10-24

Amomum villosum Lour. is the plant that produces famous traditional Chinese medicine Amomi Fructus. Frequent habitat destruction seriously threatens A. germplasm resources. Genetic diversity very important to optimization of resources and population protection, but range inherited traits within unclear. In this study, we analyzed genetic structures populations in Guangdong constructed a local reference DNA barcode library as resource for conservation efforts.DNA barcoding Inter-Simple...

10.7717/peerj.12325 article EN cc-by PeerJ 2021-10-20

Introduction: The root of Reynoutria multiflora (Thunb.) Moldenke (RM) has been used widely in formulations herbal medicines China for centuries. Raw R. (RRM) should be processed before use to reduce toxicity and increase efficacy. However, detailed regulation the processing endpoint is lacking, duration can vary considerably. We conducted in-depth research on stilbene glycosides RM at different times. Previously, we discovered that 219 changed markedly quantity content. Therefore, proposed...

10.3389/fphar.2024.1356876 article EN cc-by Frontiers in Pharmacology 2024-02-26

The root of Reynoutria multiflora Thunb. Moldenke (RM, syn.: Polygonum multiflorum Thunb.) has been widely used in TCM clinical practice for centuries. raw R. (RRM) should be processed before use, order to reduce toxicity and increase efficiency. However, the content trans-2, 3, 5, 4'-tetrahydroxystilbene-2-O-β-D-glucopyranoside (trans-THSG), which is considered main medicinal ingredient, decreases this process. In understand changes stilbene glycosides (PRM), a simple effective method was...

10.3389/fphar.2022.757490 article EN cc-by Frontiers in Pharmacology 2022-04-25

Emodin (EM) and Emodin-8-O-β-D-glucoside (EG) exists in various medicinal plants such as Rheum palmatum, Aloe vera, Polygonum multiflorum, cuspidatum. They have pharmacological properties are considered potential toxic substances. It is necessary to identify the metabolites distribution body. In this study, a comprehensive analytical strategy was developed characterize of EM EG vivo (rat plasma, bile, urine, heart, liver, spleen, lung, kidney, brain) using UHPLC-Q-Exactive Orbitrap MS. As...

10.2139/ssrn.4721366 preprint EN 2024-01-01

Artemisia annua is the major source for artemisinin production. The content in A. affected by different types of light especially UV light. UVR8, a member RCC1 gene family was found to be UV-B receptor plants. structures, evolutionary history and expression profile UVR8 or genes remain undiscovered annua.Twenty-two (AaRCC1) were identified each haplotype genome two diploid strains annua, LQ-9 HAN1. Varied structures sequences among paralogs observed. divergence most occurred at 46.7 - 51 MYA...

10.1186/s12864-023-09786-4 article EN cc-by BMC Genomics 2023-11-18

Abstract Background : The Amomum villosum has the situation that it is inferior and other varieties are used as A. in market. In order to develop utilize genuine medicinal materials , this experiment aims carry out identification research of variety analyze its genetic diversity, constructing DNA barcode database Guangdong Province providing recommendations for populations planting, which will be critical further . (2) Methods: A total 141 samples were analyzed by barcoding construct...

10.21203/rs.3.rs-133546/v1 preprint EN cc-by Research Square (Research Square) 2020-12-23

Abstract Background Amomum villosum Lour. is the plant of a famous traditional Chinese medicine Amomi Fructus and its habitat has been frequently destroyed that seriously threatened germplasm resources. The genetic diversity great significance to optimization resources protection populations, but A. unclear. In this study, we analyzed structures populations in Guangdong constructed local reference DNA barcode library for purpose more appropriate protecting measures. Methods barcoding ISSR...

10.21203/rs.3.rs-463520/v1 preprint EN cc-by Research Square (Research Square) 2021-05-05
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