- Head and Neck Cancer Studies
- Head and Neck Surgical Oncology
- Tracheal and airway disorders
- Vascular Anomalies and Treatments
- Respiratory viral infections research
- Herpesvirus Infections and Treatments
- Virus-based gene therapy research
- Viral-associated cancers and disorders
- Cancer-related molecular mechanisms research
- Cancer Research and Treatments
- Parvovirus B19 Infection Studies
- Lung Cancer Research Studies
- Healthcare and Venom Research
- Traditional Chinese Medicine Studies
- Immunotherapy and Immune Responses
- Otitis Media and Relapsing Polychondritis
- Esophageal Cancer Research and Treatment
- Cancer-related Molecular Pathways
- Salivary Gland Tumors Diagnosis and Treatment
- Immune Cell Function and Interaction
- Synthesis of Organic Compounds
The People's Hospital of Guangxi Zhuang Autonomous Region
2002-2021
Epstein-Barr virus (EBV)-encoded latent membrane protein 2 (LMP2) promotes nasopharyngeal carcinoma (NPC) progression. Previously, we reported that the dendritic cells (DCs) transfected with EBV-LMP2 recombinant serotype 5 adenoviruses (rAd5) induced anti-tumor effect by eliciting cytotoxic T lymphocytes (CTLs)-mediated immune response in vitro and adenoviral vaccine of (rAd5-EBV-LMP2) stimulated antigen-specific cellular immunity mice. However, safety immunological rAd5-EBV-LMP2 human still...
Local residual and recurrent nasopharyngeal carcinoma (NPC) generally shows treatment failure after standard radiotherapy with or without concurrent chemotherapy. Whether endoscopic nasopharyngectomy might provide an additional therapeutic advantage remains controversial. Therefore, we retrospectively compared the clinical prognoses of patients NPC treated combined chemoradiotherapy (CRT) those CRT alone.A total sixty-two local were studied retrospectively: 36 received CRT, whereas 26 who...
To report clinical manifestations, bleeding point localization, and outcomes of management in 16 patients with instances intractable epistaxis after radiation therapy for nasopharyngeal carcinoma. Retrospective chart review carcinoma (mean age 52.06 ± 14.37 years) during the past 5 years, whose diagnosis was confirmed by angiography (n = 10) or MRI/CT imaging studies manifestations 6). The mean dose to affected carotid artery 101.37 34.85 Gy. Bleeding points were detected internal 8)...
Aim: Intensity-modulated radiotherapy (IMRT) is a widely accepted therapy for nasopharyngeal carcinoma (NPC), but it inevitably brings out radiation-related complications and seriously affects the quality of life (QoL). Endoscopic nasopharyngectomy (ENPG) has been successfully conducted in locally recurred NPC, few studies evaluated its application early NPC. This study aims to assess feasibility safety ENPG combined with low-dose (LDRT) T1-2 Patients Methods: We recruited 37 newly diagnosed...
To evaluate the efficacies of different treatments for recurrent cervical lymph nodes and factors contributing to prognosis in patients with nasopharyngeal carcinoma after radiotherapy.Clinical data 79 radiotherapy were retrospectively analyzed, all cases diagnosed as having by pathological examination. The including sex, age, interval between completion recurrence, rN stage, treatment methods, location relationship lesion primary tumor neck analyzed prognosis. Kaplan-Meier curves, Log-rank...
Objective: To evaluate the diagnostic value and feasibility of narrow-band imaging in detection recurrent nasopharyngeal carcinoma (NPC). Methods: One thousand three hundred sixty-four NPC patients who had completed treatment were enrolled. All followed-up with imaging, serological examination EB virus endoscopy(WL NBI mode), which (1) both white light (WL) modes done; (2) positive endoscopic given biopsy; (3) using histologic finding as criterion standard, sensitivity, specificity, accuracy...
Objective: To evaluate the efficacy of cut needle biopsy in diagnosis submucosal nasopharyngeal neoplasms. Methods: Cut performed with automatic gun was applied 17 cases type neoplasms.The bleeding quantity recorded and pain measured by score. Results: Adequate sample for hispathological received from each patients. And were consistent follow-up visit. The ranged 1 to 5 ml ((1.9±0.3)ml). scores numerical rating scale between 2-7 (4.0±0.4). There no serious complications such as hemorrhea. 3...
Objective To investigate the difference of EB-LMP2 specific immune status among patients with nasopharyngeal carcinoma, serum EBV VCA/IgA positive group and negative in Guangxi area china. Methods 60 cases screening volunteers 20 came from Cangwu county area, 134 carcinoma (NPC) The People's Hospital Zhuang Autonomous Region. Blood samples were taken before any treatment, preipheral blood mononuclear cels(PBMC) by Ficoll density gradient centrifugation.Specific responses cytotoxic T...