A5080765013- Mathematical and Theoretical Epidemiology and Ecology Models
- Marine and fisheries research
- COVID-19 epidemiological studies
- Marine Bivalve and Aquaculture Studies
- Pain Mechanisms and Treatments
- Wildlife Ecology and Conservation
- Marine and coastal ecosystems
- Stroke Rehabilitation and Recovery
- Fish Ecology and Management Studies
- Receptor Mechanisms and Signaling
- Evolution and Genetic Dynamics
- Heart Rate Variability and Autonomic Control
- Ocean Acidification Effects and Responses
- Physiological and biochemical adaptations
- Traditional Chinese Medicine Studies
- Animal Ecology and Behavior Studies
- Product Development and Customization
- Diverse Aspects of Tourism Research
- Healthcare and Venom Research
- Mobile Agent-Based Network Management
- Mathematical Biology Tumor Growth
- Environmental Toxicology and Ecotoxicology
- Simulation Techniques and Applications
- Musicians’ Health and Performance
- Alcohol Consumption and Health Effects
Duquesne University
2013-2024
The University of Texas at Dallas
2024
Louisiana State University
2011
University of Tennessee at Knoxville
2007-2010
Agent-based models (ABMs) have become an increasingly important mode of inquiry for the life sciences. They are particularly valuable systems that not understood well enough to build equation-based model. These advantages, however, counterbalanced by difficulty analyzing and using ABMs, due lack type mathematical tools available more traditional models, which leaves simulation as primary approach. As large, becomes challenging. This paper proposes a novel approach two aspects optimization...
We developed a spatially explicit, individual-based model to analyze how hypoxia effects on reproduction, growth, and mortality of Atlantic croaker in the northwestern Gulf Mexico lead population-level responses. The follows hourly mortality, movement individuals 300 × 800 spatial grid 1-km2 cells for 140 years. Chlorophyll-a concentration, water temperature, dissolved oxygen (DO) were specified daily each cell repeated year simulation. A bioenergetics was used represent assumed stage-...
This article presents a model for population interactions between an invasive and native species, where the effect of disturbance in system (such as flooding) is modeled control variable growth terms. The motivating example cottonwood–salt cedar competition, with flooding being detrimental at low high levels advantageous medium levels, which led us to consider quadratic functions control. An objective functional formulated maximize species while minimizing cost implementing A new existence...
Quantifying the population-level effects of hypoxia on coastal fish species has been challenging. In companion paper (part 1), we described an individual-based population model (IBM) for Atlantic croaker in northwestern Gulf Mexico (NWGOM) designed to quantify long-term responses low dissolved oxygen (DO) concentrations during summer. Here part 2, replace idealized conditions with realistic DO generated from a 3-dimensional water quality model. Three years were used and randomly arranged...
The amygdala is a brain area involved in emotional regulation and pain. Over the course of last 20 years, multiple researchers have studied sensory motor connections within trying to understand ultimate role this structure pain perception descending control A number investigators been using cell-type specific manipulations probe underlying circuitry amygdala. As data accumulated research space, we recognized critical need for single framework integrate these evaluate emergent system-level...
Chronic bladder pain evokes asymmetric behavior in neurons across the left and right hemispheres of amygdala. An agent-based computational model was created to simulate firing over time response painful stimulation. Each agent represents one neuron is characterized by its location amygdala type (excited or inhibited). At each step, rates (Hz) all are stochastically updated from probability distributions estimated data collected laboratory experiments. A damage accumulation tracks accrued...
Neuropathic pain is caused by nerve injury and involves brain areas such as the central nucleus of amygdala (CeA). We developed first 3-D agent-based model (ABM) neuropathic pain-related neurons in CeA using NetLogo3D. The execution time a single ABM simulation realistic parameters (e.g., 13,000 22,000+ neural connections) an important factor model's usability. In this paper, we describe our efforts to improve computational efficiency ABM, which resulted 28% reduction on average for typical...
Abstract This article describes a computational project designed for undergraduate students as an introduction to mathematical modeling. Students use ordinary differential equation describe fish weight and assume the instantaneous growth rate depends on concentration of dissolved oxygen. Published laboratory experiments suggest that continuous exposure low concentrations oxygen (DO 6.0 mg/l) causes reduction in average summer flounder, compared with conditions rates normoxia mg/l). data from...
Neuropathic and nociplastic pain are major causes of involve brain areas such as the central nucleus amygdala (CeA). Within CeA, neurons expressing protein kinase c-delta (PKCδ) or somatostatin (SST) have opposing roles in pain-like modulation. In this manuscript, we describe our progress towards developing a 3-D computational model PKCδ SST CeA use to explore pharmacological targeting these two neural populations modulating nociception. Our expands upon existing 2-D framework by including...
Background: Adherence to home practice rehabilitation programs is important for efficacy; however, adherence challenging many individuals post-stroke. Accelerometers have emerged as a potential means support practice. This secondary data analysis explored the use of commercially available accelerometer with custom software collect and analyze corroborate self-reported collected during program. Methods: The initial study was single subject design trial that investigated effect preferred music...
Abstract Date Presented 04/06/19 The purpose of this study was to explore the psychometrics commercially available activity monitors for remote monitoring repetitive task practice. This completed in a controlled setting with healthy middle-age adults, as precursor clinical exploration. Primary Author and Speaker: MacKenzie Gough Additional Authors Speakers: Taylor McElroy, Elena Donoso Brown, Fiona Kessler, Jenna Gallipoli Contributing Authors: Rachael Miller Neilan
Abstract Date Presented Accepted for AOTA INSPIRE 2021 but unable to be presented due online event limitations. This poster will discuss the use of commercially available accelerometers monitor poststroke home rehabilitation upper extremity during repetitive, occupation-based exercises. Secondary data analysis outputs includes (1) comparison self-reported practice sessions with captured via accelerometer, (2) time versus and (3) patterns in angular velocity based on processing. Primary...