Zia S. Pradhan

ORCID: 0000-0003-4080-1665
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About
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Research Areas
  • Glaucoma and retinal disorders
  • Retinal Diseases and Treatments
  • Retinal Imaging and Analysis
  • Corneal surgery and disorders
  • Ocular Surface and Contact Lens
  • Retinal and Macular Surgery
  • Ophthalmology and Visual Impairment Studies
  • Optical Coherence Tomography Applications
  • Intraocular Surgery and Lenses
  • Retinal and Optic Conditions
  • Retinopathy of Prematurity Studies
  • Neurological Disorders and Treatments
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Antifungal resistance and susceptibility
  • Historical Geography and Cartography
  • Cerebrovascular and Carotid Artery Diseases
  • Ocular Infections and Treatments
  • Corneal Surgery and Treatments
  • Ophthalmology and Eye Disorders
  • Parasitic Diseases Research and Treatment
  • Traumatic Ocular and Foreign Body Injuries
  • Cerebral Venous Sinus Thrombosis
  • Optics and Image Analysis
  • Retinal Development and Disorders
  • Connexins and lens biology

Narayana Nethralaya
2016-2025

Glaucoma Research Foundation
2018-2022

Christian Medical College & Hospital
2012-2016

Christian Medical College
2012-2016

University of Toronto
2015-2016

University at Buffalo, State University of New York
2015

University of Mississippi Medical Center
2015

Hospital Fernández
2015

Minnesota Lions Eye Bank
2015

Fundación Juan March
2015

<h3>Aims</h3> To evaluate the diagnostic ability of peripapillary vessel density measurements on optical coherence tomography angiography (OCTA) in primary open-angle glaucoma (POAG) and angle-closure (PACG), to compare these with retinal nerve fibre layer (RNFL) thickness measurements. <h3>Methods</h3> In a cross-sectional study, 48 eyes 33 healthy control subjects, 63 39 patients POAG 49 32 PACG underwent OCTA (RTVue-XR, Optovue, Fremont, California, USA) RNFL imaging spectral domain OCT....

10.1136/bjophthalmol-2016-309377 article EN British Journal of Ophthalmology 2016-11-29

To compare the intrasession repeatability of peripapillary and macular vessel density measurements optical coherence tomography angiography (OCTA) in normal glaucoma eyes, to evaluate effect signal strength OCTA scans on repeatability.In a cross-sectional study, three optic nerve head each 65 eyes (30 normal, 35 eyes) 69 (35 34 acquired same session with were analysed. Repeatability was assessed using within-subject coefficient (CRw) variation (CVw). Effect index (SSI) evaluated...

10.1136/bjophthalmol-2017-310637 article EN British Journal of Ophthalmology 2017-07-24

Purpose To compare the diagnostic abilities of vessel density measurements optic nerve head (ONH), peripapillary and macular regions on optical coherence tomography (OCT) angiography in eyes with primary open angle glaucoma (POAG) that ONH rim area, retinal fiber layer (RNFL) thickness ganglion cell complex (GCC) measurements. Methods In a cross sectional study, 78 50 control subjects 117 67 POAG patients underwent structural spectral domain OCT. was diagnosed based masked evaluation disc...

10.1371/journal.pone.0173930 article EN cc-by PLoS ONE 2017-03-13

The aim of this study was to evaluate the effect subject-related (age, sex, and systemic hypertension diabetes), eye-related (refractive error, optic disc size), technology-related (signal strength index, SSI scans) determinants on peripapillary macular vessel densities measured with optical coherence tomography angiography (OCTA) in normal eyes.In a cross-sectional study, 181 eyes 107 subjects (45 men, 62 women, median age: 50 y, range: 18 77 y) underwent OCTA imaging. Linear mixed models...

10.1097/ijg.0000000000000655 article EN Journal of Glaucoma 2017-03-04

Purpose: To evaluate the sectoral and global structure-structure (vessel density-retinal nerve fiber layer thickness) structure-function density-visual sensitivity loss) relationships of peripapillary vessel density measurements on optical coherence tomography angiography in primary open-angle glaucoma to determine if fractional polynomial (FP) models characterize better than linear models. Materials Methods: In a cross-sectional study, densities were determined 227 eyes 143 subjects (63...

10.1097/ijg.0000000000000670 article EN Journal of Glaucoma 2017-03-24

Purpose: To describe a technique to manage corneal perforations between 3 and 6 mm in size using autologous Tenons tissue with cyanoacrylate glue bandage contact lens. Methods: A thin layer of capsule harvested from the patient's own eye is used seal perforation act as scaffold. The patch graft spread over held place by application glue. lens then placed on eye. Results: 6-year retrospective review 28 patients who underwent this procedure was performed. One patient lost follow-up. Of 27 were...

10.1097/ico.0000000000000808 article EN Cornea 2016-03-19

Purpose To evaluate the association between optical coherence tomography (OCT) angiography measurements and progressive retinal nerve fiber layer (RNFL) loss in eyes with mild to moderate open-angle glaucoma. Methods In this prospective study, 111 quadrants of 59 mild-moderate glaucoma were longitudinally evaluated for a minimum 2 years at least 3 OCT scans performed. was performed baseline vessel densities peripapillary parafoveal regions determined quadrant-wise. Effect demographic (age,...

10.1371/journal.pone.0319903 article EN cc-by PLoS ONE 2025-03-25

The main purpose of this study was to compare the prevalence choroidal microvascular dropout (CMvD) in primary open-angle glaucoma (POAG) eyes with and without disc hemorrhage (DH).In a cross-sectional study, 44 control subjects, 32 POAG patients DH, 41 DH underwent visual fields (VFs), optical coherence tomography (OCT) OCT angiography (OCTA). Presence CMvD evaluated on OCTA slab. VF defect were classified into initial nasal defect, parafoveal scotoma, combined defect.CMvD detected 17...

10.1097/ijg.0000000000001173 article EN Journal of Glaucoma 2018-12-31

Aims To compare the peripapillary vessel density (VD) measurements of high-density (HD) and non-HD optical coherence tomography angiography (OCTA) scans in normal glaucoma eyes, to evaluate intrasession repeatability VD HD scans. Methods In a cross-sectional study, 46 (33 subjects) 89 (64 patients) eyes underwent 3 1 optic nerve head OCTA same session. Agreement between was assessed using Bland Altman analysis. Repeatability within-subject coefficient (CRw) variation (CVw). Results The mean...

10.1136/bjophthalmol-2018-312401 article EN British Journal of Ophthalmology 2018-08-17

To study sectoral vessel density (VD) and structural alterations in the peripapillary parafoveal hemiretina corresponding to perimetrically intact regions of glaucomatous eyes with hemifield defects compare these healthy using optical coherence tomography.This cross-sectional included 37 open-angle glaucoma having visual fields restricted 1 45 age-matched controls. Peripapillary VD retinal nerve fiber layer (RNFL) thickness were measured 8 sectors. Parafoveal ganglion cell complex superior...

10.1097/ijg.0000000000000950 article EN Journal of Glaucoma 2018-03-20

Purpose: To evaluate the diagnostic abilities of macular vessel length and perfusion densities measured with optical microangiography (OMAG) over a 3×3 mm 6×6 region, to compare these ganglion cell-inner plexiform layer (GCIPL) thickness in eyes primary open-angle glaucoma (POAG). Methods: In cross-sectional study, 96 57 control subjects 88 POAG patients underwent imaging coherence tomography. Area under receiver operating characteristic curves (AUC) sensitivities at 90% specificity OMAG...

10.1097/ijg.0000000000000952 article EN Journal of Glaucoma 2018-03-23

Purpose: To compare the prevalence of choroidal microvasculature dropout (CMvD) in pseudoexfoliation glaucoma (PXG) and disease severity–matched primary open-angle (POAG) eyes. Methods: In a cross-sectional study, 39 eyes with PXG (33 patients) POAG (34 underwent visual fields, optical coherence tomography angiography examination. Peripapillary vessel density (VD) was evaluated from radial peripapillary capillary slab, parafoveal VD measured on superficial vascular plexus slab macula, CMvD...

10.1167/iovs.19-26844 article EN cc-by-nc-nd Investigative Ophthalmology & Visual Science 2019-05-20

Purpose To compare the corneal biomechanical parameters between pseudoexfoliation glaucoma (PXG), primary open-angle (POAG) and healthy controls using Corvis ST. Methods A prospective, cross-sectional study was conducted which included 132 treatment-naïve eyes underwent The cohort comprised of 44 with PXG, 42 POAG 46 controls. Corneal parameters, velocities, length applanated surface, deformation amplitude (DA), peak distance radius curvature, were compared groups analysis variance models....

10.1371/journal.pone.0241296 article EN cc-by PLoS ONE 2020-10-26

To compare the vessel density measurements of optic nerve head, peripapillary and macular regions in severity-matched primary open-angle glaucoma (POAG) eyes with without disc hemorrhage (DH) using optical coherence tomography (OCT) angiography, to their diagnostic abilities that rim area, retinal fiber layer ganglion cell complex thickness on OCT.In a cross-sectional study, 66 46 control subjects, 34 33 POAG patients DH (median mean deviation=-3.7 dB) 63 43 deviation=-3.8 underwent imaging...

10.1097/ijg.0000000000000758 article EN Journal of Glaucoma 2017-08-10

Lower whole enface disc (coefficient: 0.02, P=0.03) and macular vessel densities 0.04, P=0.02) on optical coherence tomography angiography (OCTA) were significantly associated with faster rate of mean deviation (MD) decline.To evaluate the association between OCTA features prior visual field (VF) progression in primary angle closure glaucoma (PACG).In a cross-sectional study, 46 eyes 31 PACG patients 5 reliable VF examinations performed over ≥3 years follow-up underwent imaging. Effect...

10.1097/ijg.0000000000001745 article EN Journal of Glaucoma 2020-12-02

The offline artificial intelligence (AI) on a smartphone-based fundus camera shows good agreement and correlation with the vertical cup-to-disc ratio (vCDR) from spectral-domain optical coherence tomography (SD-OCT) manual grading by experts.The purpose of this study is to assess vCDR measured new AI software optic disc images obtained using validated imaging device, SD-OCT measurements, experts stereoscopic camera.In prospective, cross-sectional study, participants above 18 years (Glaucoma...

10.1097/ijg.0000000000002147 article EN Journal of Glaucoma 2022-11-28

Purpose: To compare the visual field (VF) parameters of new Swedish Interactive Thresholding Algorithm (SITA), SITA Faster (SFR) with that Standard (SS) on Humphrey Field Analyzer. Methods: Ninety-seven eyes 97 subjects (63 glaucoma, 26 glaucoma suspects, and 8 normal eyes) underwent VF examination SFR SS strategies same day in random order. Agreement between was assessed by Bland Altman plots. In addition, some a second strategy to evaluate its test-retest variability. Results: The median...

10.1097/ijg.0000000000001551 article EN Journal of Glaucoma 2020-05-26

The aim of this study was to investigate the usefulness and tolerance rigid gas-permeable (RGP) contact lenses in visual rehabilitation children postocular trauma.In retrospective case series, below 15 years age with ocular trauma were included. best-corrected acuity RGP compared that spectacle correction. factors affecting improvement analyzed, problems caused by lens use identified.Twelve eyes 12 boys mean 0.81 ± 0.29 (LogMar equivalent) spectacles 0.47 0.27 (P < 0.001). Seven achieved a...

10.1097/ico.0000000000000103 article EN Cornea 2014-03-12

To determine whether the ISNT rule (Inferior>Superior>Nasal>Temporal) or "IST" (Inferior>Superior>Temporal) can be applied to peripapillary retinal nerve fiber layer (RNFL) thickness as measured using Heidelberg Retinal Tomography (HRT) and Optical Coherence (OCT).This was a cross-sectional study of 189 normal 42 glaucomatous eyes. RNFL thicknesses in different quadrants HRT OCT were compared percentage eyes obeying IST rule.The HRT-measured mean showed that 25.9% obeyed 70.4% conformed...

10.1097/ijg.0000000000000064 article EN Journal of Glaucoma 2014-04-28

Precis: The agreement between a head-mounted perimeter [GearVision (GV)] and Humphrey field analyzer (HFA) for total threshold sensitivity was mean difference of −1.9 dB (95% limits −5 to 1). GV the preferred in 68.2% participants. Purpose: purpose this study compare reliability indices sensitivities obtained using novel, smartphone-based, (GV) with HFA normal, glaucoma suspect patients. A secondary objective evaluate subjective experience participants had both perimeters questionnaire....

10.1097/ijg.0000000000001797 article EN cc-by Journal of Glaucoma 2021-02-15

Abstract Background/Objectives An affordable and scalable screening model is critical for undetected glaucoma. The study evaluated the performance of an offline, smartphone-based AI system detection referable glaucoma against two benchmarks: specialist diagnosis following full workup consensus image grading. Subjects/Methods This prospective (tertiary centre, India) included 243 subjects with varying severity control group without Disc-centred images were captured using a validated fundus...

10.1038/s41433-023-02826-z article EN cc-by Eye 2023-12-13
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