Pablo M. Linares

ORCID: 0000-0003-4090-6942
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About
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Research Areas
  • Inflammatory Bowel Disease
  • Angiogenesis and VEGF in Cancer
  • Lipid metabolism and disorders
  • Lymphatic System and Diseases
  • Galectins and Cancer Biology
  • Helicobacter pylori-related gastroenterology studies
  • Microscopic Colitis
  • Acute Lymphoblastic Leukemia research
  • Pancreatic and Hepatic Oncology Research
  • Biomarkers in Disease Mechanisms
  • Gastroesophageal reflux and treatments
  • Immunodeficiency and Autoimmune Disorders
  • Renal Diseases and Glomerulopathies
  • Osteoarthritis Treatment and Mechanisms
  • Medical and Biological Ozone Research
  • Rheumatoid Arthritis Research and Therapies
  • Reproductive System and Pregnancy
  • Eosinophilic Esophagitis
  • Biosimilars and Bioanalytical Methods
  • Pancreatitis Pathology and Treatment
  • Pregnancy and Medication Impact

Hospital Universitario de La Princesa
2009-2017

Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2009-2017

Universidad Autónoma de Madrid
2013

Immunomodulators are used as maintenance treatment of inflammatory bowel disease (IBD). Data regarding their possible effects in the course pregnancy when father is exposed at time conception limited.To evaluate outcomes pregnancies which fathers were to thiopurines conception. A series male patients followed seven IBD clinics Madrid, Spain, was studied. Any exposure during 3 months preceding considered significant. Controls fathered by who either had never been treated with or interrupted...

10.1038/ajg.2010.138 article EN The American Journal of Gastroenterology 2010-08-10

Angiogenic and lymphangiogenic factors (ALFs) may play an important role in inflammatory bowel disease (IBD). Our aims were to evaluate levels of ALFs serum the colonic mucosa culture supernatant (MCS) patients with active quiescent IBD healthy subjects correlate them endoscopic, clinical histological activity acute-phase reactants.This is a prospective study 28 controls 72 patients. Serum MCS concentration VEGFA, VEGFC, VEGFD, VEGFR1, VEGFR2, VEGFR3, PlGF, Ang1, Ang2 Tie2 measured by ELISA....

10.1016/j.crohns.2013.04.005 article EN Journal of Crohn s and Colitis 2013-05-01

<b><i>Background/Aims:</i></b> To evaluate the incidence rate of relapse in patients with inflammatory bowel disease (IBD) undergoing chondroitin sulphate (CS) treatment and its effect on concentrations several pro-inflammatory proteins. <b><i>Methods:</i></b> Prospective, observational, 12-month follow-up study IBD remission, starting CS (Condrosan®, Bioiberica S.A.) for osteoarthritis (OA). Crohn's Disease Activity Index modified...

10.1159/000439522 article EN Digestion 2015-01-01

Infliximab and adalimumab effectiveness might be related with changes in angiogenic factors. The aim of the study was to compare concentrations proteins patients inflammatory bowel disease (IBD) healthy controls analyze levels during infliximab treatment.A prospective case-control conducted 37 IBD starting treatment (16 Crohn's 6 ulcerative colitis) or (15 disease) 40 control subjects. Four samples were taken from patients, one before each first 3 doses infliximab/adalimumab at week 14....

10.1097/mib.0000000000000004 article EN Inflammatory Bowel Diseases 2014-02-21

Angiogenic factors are involved in the physiopathology of several inflammatory diseases and they probably play a role pathogenesis acute pancreatitis (AP).To investigate if angiogenic elevated patients with AP, their relationship severity clinical evolution use as prognosis markers AP.A case (25)-control (30) study was carried out. Patients AP were classified according to (using Ranson Glasgow scores) (taking into account development complications during hospital stay). Platelet-derived...

10.1097/mcg.0b013e31820d3533 article EN Journal of Clinical Gastroenterology 2011-03-25
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