Weijia Song

ORCID: 0000-0003-4094-1115
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About
Contact & Profiles
Research Areas
  • Aquaculture disease management and microbiota
  • Reproductive Biology and Fertility
  • Invertebrate Immune Response Mechanisms
  • Epigenetics and DNA Methylation
  • Renal and related cancers
  • Ovarian function and disorders
  • Adipokines, Inflammation, and Metabolic Diseases
  • Sperm and Testicular Function
  • Regulation of Appetite and Obesity
  • Antimicrobial Peptides and Activities
  • Birth, Development, and Health
  • Reproductive Health and Technologies
  • Aquaculture Nutrition and Growth
  • Cellular Mechanics and Interactions
  • Receptor Mechanisms and Signaling
  • Biochemical and Structural Characterization
  • Prenatal Screening and Diagnostics
  • Heat shock proteins research
  • Cholesterol and Lipid Metabolism
  • Signaling Pathways in Disease
  • Neuropeptides and Animal Physiology

Northwest A&F University
2017-2025

Cavite State University
2025

Ministry of Agriculture, Livestock, and Food Supply
2022-2024

National University
2024

Tang Du Hospital
2021

Air Force Medical University
2021

Extensive epigenetic reprogramming occurs during preimplantation embryonic development. However, the impact of DNA methylation in plateau yak embryos and how contributes to transcriptional regulatory networks are unclear. In this study, we quantified gene expression oocytes a series at different developmental stages single-cell resolution using bisulfate-sequencing RNA-seq. We characterized genome activation maternal transcript degradation mapped events critical for Through cross-species...

10.1016/j.jbc.2023.105562 article EN cc-by-nc-nd Journal of Biological Chemistry 2023-12-13

Abstract To evaluate the effect of different exercises on interventions potential biological mechanisms sperm quality with help reticulated Meta-analysis. Methods: Web Science, PubMed, EMBASE, CNKI and Wanfang Wipu databases were searched to screen randomized controlled trials that met inclusion criteria, Cochrane Risk Bias Assessment Tool was used literature, Stata 17.0 software perform RESULTS: A total 13 papers 723 subjects included, (including item healthy male youth 600 cases, animal...

10.21203/rs.3.rs-3816633/v1 preprint EN cc-by Research Square (Research Square) 2024-01-23

Aberrant epigenetic nuclear reprogramming, especially imprinting pattern disorders, is one of the major causes failure clone development from somatic cell transfer (SCNT). Previous studies showed that ZFP57 a key protein required for imprint maintenance after fertilization. In this study, we found control regions in several imprinted genes were significantly hypomethylated cloned embryos compared with vitro fertilization embryos, indicating loss gene methylation. The expression was capable...

10.3168/jds.2022-22427 article EN cc-by Journal of Dairy Science 2022-11-16

The G-protein-coupled receptor GPR84, activated by medium-chain fatty acids, primarily expressed in macrophages and microglia, is involved inflammatory responses retinal development mammals amphibians. However, our understanding of its structure, function, tissue expression, signaling pathways fish limited. In this study, we cloned characterized the coding sequence GPR84 (ciGPR84) grass carp. A phylogenetic analysis revealed close relationship with bony fishes. High expression levels were...

10.3390/ani13193001 article EN cc-by Animals 2023-09-23

Abstract Preimplantation embryos undergo a series of important biological events, including epigenetic reprogramming and lineage differentiation, the key genes specific mechanisms that regulate these events are critical to reproductive success. Ubiquitin-specific protease 7 (USP7) is deubiquitinase involved in regulation variety cellular functions, yet its precise function mechanism preimplantation embryonic development remain unknown. Our results showed RNAi-mediated silencing USP7 mouse or...

10.1093/biolre/ioae034 article EN Biology of Reproduction 2024-03-04

Abstract The melanocortin-3 receptor (MC3R) is an important regulator of energy homeostasis and inflammation in mammals. However, its function teleost fish needs to be further explored. In this study, we characterized rainbow trout MC3R (rtMC3R), which encoded a putative protein 331 amino acids. Phylogenetic chromosomal synteny analyses showed that rtMC3R was closely related bony fishes. Quantitative PCR (qPCR) revealed the transcripts were highly expressed brain muscle. cellular verified by...

10.21203/rs.3.rs-507819/v1 preprint EN cc-by Research Square (Research Square) 2021-05-13
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