A5088981793- HIV/AIDS drug development and treatment
- Heavy metals in environment
- Chromium effects and bioremediation
- Biochemical and Molecular Research
- Hepatitis B Virus Studies
- Chemical Synthesis and Analysis
- Hepatitis C virus research
- Arsenic contamination and mitigation
- Agricultural Economics and Practices
- Adsorption and biosorption for pollutant removal
- Medicinal Plants and Neuroprotection
- Soil Carbon and Nitrogen Dynamics
- Coal and Its By-products
- Allelopathy and phytotoxic interactions
- HIV Research and Treatment
- Lysosomal Storage Disorders Research
- Catalytic C–H Functionalization Methods
- Water Quality and Pollution Assessment
- Essential Oils and Antimicrobial Activity
- Multicomponent Synthesis of Heterocycles
- Synthesis and Characterization of Heterocyclic Compounds
- Livestock Management and Performance Improvement
- Viral Infections and Outbreaks Research
- Synthesis and biological activity
- Mosquito-borne diseases and control
Sugen Life Sciences (India)
2025
BioMarin (United States)
2025
Tilka Manjhi Bhagalpur University
1993-2024
Nanaji Deshmukh Veterinary Science University
2024
Vinoba Bhave University
2021
Bioscience (Slovakia)
2020
University of Hyderabad
2020
Jai Prakash Vishwavidyalaya
2018-2019
Birla Institute of Technology, Mesra
2016
National Institute of Technology Patna
2015
Soil biomass C, N and P were determined for a native forest site, an unmined deforested site age-series of adjacent coal mine spoils (5, 10, 12, 16 20 yr). Biomass C ranged from 209 to 867 μg g −1 soil, 75 soil 7 29 soil. linearly related each other. was also the root biomass. with mean C:N ratio 11.8 accounted 2.2–4.2% total positively mineral C:P 27.6 31.0%. The significantly bicarbonate soluble Pi. microbial characterized by C:N:P 29:3:1. age spoils, values youngest spoil (5 yr old) being...
The discovery of selective and potent inhibitors through de novo pathways is essential to combat drug resistance in chronic hepatitis B (CHB) infections. Recent studies have highlighted that neplanocin A (NepA) derivatives are biologically the virus (HBV). In this study, we designed, synthesized, evaluated various pyrazolo[3,4-d]pyrimidine-based NepA analogues (4a-h) for their anti-HBV activity. Notably, analogue 4g demonstrated significant activity against HBV replication, with EC50 (HBV...
This study assessed the real-world effectiveness and safety of enzyme replacement therapy (ERT), cerliponase alfa, to treat neuronal ceroid lipofuscinosis type 2 (CLN2) disease. Data from DEM-CHILD database were analyzed, comparing patients who initiated ERT outside clinical trials with natural history (NH) controls. Treated matched 1:1 NH controls on baseline age combined motor-language (ML) score CLN2 rating scale. Rate ML decline, time unreversed 2-point decline or 0, 0 assessed. Safety...
The present study evaluated the effects of omega-3 (ω-3) fatty acid-rich linseed supplementation on reproductive performance, endocrine profile, and biochemical profile ewes reared in subtropical climates. Forty-eight acyclic clinically healthy Marwari sheep, aged 1.5–2.5 years with no parity, were divided into four groups ( n = 12 each). Ewes control group (group I) fed only a basal feed, whereas treatment II, III, IV diet along 10%, 15%, 20% linseed, respectively, daily dry matter basis....
Abstract Mycobacterium tuberculosis codes for an essential NAD + ‐dependent DNA ligase ( Mtu LigA) which is a novel, validated, and attractive drug target. We created mutants of the enzyme by systematically deleting domains from C‐terminal end to probe their functional roles in nick joining reaction. Deletion just BRCT domain LigA resulted total loss activity vitro assays. However, mutant could form AMP‐ligase intermediate that suggests defects caused deletion occur primarily at steps after...
Journal Article The influence of colouring and pungent agents red Chilli (Capsicum annum) on growth aflatoxin production by Aspergillus flavus Get access A. Masood, Masood University Department Botany, Bhagalpur University, Bhagalpur, India Search for other works this author on: Oxford Academic Google Scholar J.V.V. Dogra, Dogra A.K. Jha Letters in Applied Microbiology, Volume 18, Issue 4, 1 April 1994, Pages 184–186, https://doi.org/10.1111/j.1472-765X.1994.tb00841.x Published: 01 1994...
Schiff bases o-vanilidene-1-aminobenzene (HL1) and o-vanilidene-2-methyl-1-aminobenzene (HL2) lead to the formation of mono- bis-[(Cl)Zn(L1)] (1), [(Cl)Zn(L2)] (2), [(Cl)Hg(L1)] (3), [(Cl)Hg(L2)] (4), [Zn(L1)2] (5), [Zn(L2)2] (6), [Hg(L1)2] (7), [Hg(L2)2] (8) complexes by reactions zinc(II) mercury(II) chlorides in different mole ratio(s). Complexes 1–8 have been characterized elemental analyses (Zn, Hg, C, H, Cl, N), melting point spectral (IR, 1H-NMR), PXRD, molar conductivity measurement,...
Heavy metals are causing serious health hazard due to its toxicity and persistence in soil aqueous medium too. contamination drinking water has become a major cause of concern for the environmentalists. Arsenic(III) Chromium(VI) is widely distributed Gangetic plain skin pigmentation liver disorders. Fluoride also pollutant southern part Ganges. Several methods removal heavy from e.g. precipitation, adsorption, ion exchange practice. But naturally grown aquatic weeds, biomass medicinal plants...
Cymbopogon flexuosus (lemon grass) cultivated by farmers for fragrance, oils and folk medicine remediates/ accumulates highly toxic As(III) originating from geological deposits as well anthropogenic activities. Cympobogon contains citral, geraniol, isoneral in addition to several other bioactive compounds widely used anticancer, antioxidant antimicrobial properties. Insertion of arsenic the food chain human being has become a potential threat civilization these days. More than 10 million...
Abstract Growth performance of nine native tropical tree species planted on mine spoil under two levels NPK treatment was studied by measuring height and diameter. Of the species, four were leguminous. All responded positively to fertilization; however, impact leguminous little compared non‐leguminous species. In general, height/diameter ratio decreased from control full‐dose treatment, suggesting that nutrient enrichment influenced resource allocation pattern such diameter growth favored....
In this paper, we calculate the effective gravitational mass of Ayón-Beato and García (AG) regular (nonsingular) static spherically symmetric asymptotically Minkowskian metric that is a solution to Einstein’s equations coupled with nonlinear electromagnetic field. The negative, zero, or positive depends on ratio magnitude electric charge ADM radial distance mass. As expected, at large values distance, our result gives Reissner–Nordström metric.
A convergent strategy for the synthesis of ara-neplanocin analogues has been developed. Microwave assisted Mitsunobu reaction proved to be an essential tool both 2'-beta-hydroxy inversion and coupling with heterocyclic bases. The exploitation present approach allowed generating a family ara-neplanocins which biological potential is still unexplored.
Carbocyclic nucleosides are considered as nucleoside mimetic having high therapeutic potentials, however diverse exploration is still limited due to their synthetic difficulties. The major challenges associated with the preparation of new base and carbocyclic sugar key intermediates. modified may provide conformational advantage achieve better mimetics also help in increasing drug-like properties. In this manuscript, we report use acetamidine hydrochloride synthesize...