A5093066492- Spectroscopy Techniques in Biomedical and Chemical Research
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Protein Interaction Studies and Fluorescence Analysis
- Cancer-related molecular mechanisms research
- Heavy Metal Exposure and Toxicity
- Spectroscopy and Chemometric Analyses
- thermodynamics and calorimetric analyses
- Biomarkers in Disease Mechanisms
- Liver Disease Diagnosis and Treatment
- Hemodynamic Monitoring and Therapy
- Ultrasound and Hyperthermia Applications
- Endometrial and Cervical Cancer Treatments
- Computational Drug Discovery Methods
- Ovarian cancer diagnosis and treatment
- Animal Virus Infections Studies
- Trace Elements in Health
Fryderyk Chopin University of Music
2023-2025
Abstract Platinum-resistant phenomena in ovarian cancer is very dangerous for women suffering from this disease, because reduces the chances of complete recovery. Unfortunately, until now there are no methods to verify whether a woman with platinum-resistant. Importantly, histopathology images also were not shown differences between platinum-resistant and platinum-sensitive tissues. Therefore, study, Fourier Transform InfraRed (FTIR) FT-Raman spectroscopy techniques used find chemical...
Endometrial cancer is the fourth most common in women Europe. Its carcinogenesis a complex process and requires further research. In our study, we focus on finding new easy-to-diagnose markers for detecting endometrial cancer. For this purpose, compared levels of miR-21-5p, miR-205-5p, miR-222-3p tissues with these miRs serum patients using dPCR method. Our study preliminary consists comparing changes miRNA expression to tissue The included 18 EC 19 undergoing surgery pelvic organ prolapse...
The phenomenon of platinum resistance is a very serious problem in the treatment ovarian cancer. Unfortunately, no molecular, genetic marker that could be used assigning women suffering from cancer to platinum-resistant or platinum-sensitive group has been discovered so far. Therefore, this study, for first time, we FT-Raman spectroscopy determine chemical differences and markers presented serum, which differentiate women. result obtained showed serum collected women, significant increase...
MicroRNAs (miRNA) are involved in the process of carcinogenesis, including development endometrial cancer (EC). This study aimed to investigate association between expression three miRNAs (miR-21-5p, miR-205-5p, and miR-222-3p) tissues. In addition, stability SNORD48 U6, which were initially planned be used as reference for normalization, was investigated. Endometrial tissue obtained from 111 patients with EC during hysterectomy 19 undergoing surgery uterine fibroids or pelvic organ prolapse...
Patients with high-grade ovarian cancer have a poor prognosis, thus effective treatment remains an unmet medical issue of high importance. Moreover, finding the reason for resistance to cisplatin is crucial task improvement anti-cancer drugs. In this study, we showed first time chemical difference in serum collected from platinum-resistance and platinum-sensitive women suffering using Fourier Transform InfraRed (FTIR) spectroscopy followed by data analysis Principal Component Analysis (PCA),...
Background: Micronutrients are important components for the homeostasis of human body. The studies available in literature subject on their impact risk population diseases, including malignant neoplasms, ambiguous. In this paper, relationship between Cu and Zn serum levels occurrence endometrial cancer have been analyzed. Methods: 306 patients (153 test group 153 control group) matched age were analyzed levels. Microelements determined sera collected during hospitalization by means an...
Giant ovarian tumors are rare, as most cases diagnosed during routine gynecological check-ups or abdominal ultrasound examinations. They a challenge for gynecologists and surgeons. Diagnosis in such patients is difficult due to the limitations of medical apparatus. Perioperative management requires specialized anesthetic care associated with high mortality. The paper presents case 23-year-old woman giant serous tumor, characterized by an enlargement circumference, periodic pain, irregular...