- Neuroscience and Neuropharmacology Research
- Stress Responses and Cortisol
- Effects and risks of endocrine disrupting chemicals
- Tryptophan and brain disorders
Centre National de la Recherche Scientifique
2023
Sorbonne Université
2023
Institut de Biologie Paris-Seine
2023
Neurosciences Paris-Seine
2023
Inserm
2023
Background: We have previously shown that chronic exposure of adult male mice to low doses di(2-ethylhexyl) phthalate (DEHP) altered sexual behavior and induced down-regulation the androgen receptor (AR) in neural circuitry controlling this behavior. Objectives: The cellular mechanisms by DEHP alone or an environmental mixture were studied. Methods: Two-month-old C57BL/6J males exposed orally for 8 wk (0, 5, 50μg/kg/d) (50μg/kg/d) a mixture. Behavior, dendritic density per 50-μm length,...