A5034146645- Skin and Cellular Biology Research
- Nail Diseases and Treatments
- Autoimmune Bullous Skin Diseases
- Dermatological and Skeletal Disorders
- Vascular Malformations and Hemangiomas
- Dermatology and Skin Diseases
- RNA regulation and disease
- Hair Growth and Disorders
- Vitamin D Research Studies
- Genetic and rare skin diseases.
- melanin and skin pigmentation
- Contact Dermatitis and Allergies
- Autoimmune and Inflammatory Disorders
- Cancer and Skin Lesions
- Tumors and Oncological Cases
- Cutaneous lymphoproliferative disorders research
- Allergic Rhinitis and Sensitization
- Dermatologic Treatments and Research
- Fungal Infections and Studies
- Leprosy Research and Treatment
- Oral Health Pathology and Treatment
- Vascular Tumors and Angiosarcomas
- Cell Adhesion Molecules Research
- Infectious Diseases and Tuberculosis
- Animal testing and alternatives
All India Institute of Medical Sciences
2016-2025
Qatar Airways (Qatar)
2023
All India Institute of Medical Sciences Bhopal
2018-2019
All India Institute of Medical Sciences Raipur
2018-2019
May Institute
2018
Safdarjang Hospital
2018
Austrian Society of Dermatology and Venereology
2006-2017
Yahoo (United Kingdom)
2016
Lurie Children's Hospital
2008-2009
Northwestern University
2008-2009
Journal Article Recurrent heterozygous missense mutation, p.Gly573Ser, in the TRPV3 gene an Indian boy with sporadic Olmsted syndrome Get access J.E. Lai‐Cheong, Lai‐Cheong St John's Institute of Dermatology, King's College London (Guy's Campus), SE1 9RT, U.K Search for other works by this author on: Oxford Academic Google Scholar G. Sethuraman, Sethuraman Department All India Medical Sciences, New Delhi, M. Ramam, Ramam K. Stone, Stone M.A. Simpson, Simpson Molecular Genetics, J.A. McGrath...
Infantile hemangiomas (IH) are common vascular tumours. IH have a characteristic natural course. They proliferate rapidly during the early infantile period followed by of gradual regression over several years. Most uncomplicated undergo spontaneous involution, with small proportion cases requiring intervention. These children in life-threatening locations, local complications like haemorrhage, ulceration and necrosis functional or cosmetic disfigurements. Systemic corticosteroids been first...
Stevens Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and SJS-TEN overlap are serious adverse cutaneous drug reactions. Drugs often implicated in these reactions.A retrospective analysis of inpatients' data with dermatological diagnoses were carried out for three years, to study the causative drugs, clinical outcome, mortality conditions.Thirty patients (15 TEN, nine overlap, six SJS) admitted. In 21 cases, multiple drugs whereas single responsible nine. Anticonvulsants (35.08%)...
Pulsed corticosteroids have been used successfully for the management of pemphigus. However, prolonged use glucocorticoids may be associated with adverse effects and some patients show a poor response to conventional therapy. Biologics shown promising role in such cases; however, there is limited data from Indian subcontinent.The primary objective was assess efficacy rituximab The secondary measure cumulative doses required these patients.We undertook retrospective review records 25...
Severe vitamin D deficiency and rickets are highly prevalent among children with congenital ichthyosis. We report an incidental observation of a dramatic excellent clinical response regard to skin scaling stiffness in ichthyosis after short-term high-dose supplementation that has not been previously described. Seven (5 autosomal recessive ichthyosis; 2 epidermolytic ichthyosis) severe (and/or rickets) were given 60 000 IU oral cholecalciferol daily for 10 days under supervision. All...
Background Vascular anomalies show highly variable morphology, making clinical identification difficult. Dermoscopy is a non-invasive tool which can aid in their diagnosis, but studies of dermoscopy vascular are limited. Aim This study aimed to describe the dermoscopic findings children and evaluate usefulness over examination alone. Methods Consecutive with congenital or acquired lesions diagnosed by two experienced dermatologists after detailed history were recruited. Predominant...
PLS is a rare autosomal recessive disorder characterized by early onset periodontopathia and palmar plantar keratosis. caused mutations in the cathepsin C (CTSC) gene. Dipeptidyl-peptidase I encoded CTSC gene removes dipeptides from amino-terminus of protein substrates mainly plays an immune inflammatory role. Several have been reported this patients several ethnic groups. We report here mutation analysis three Indian families with PLS. Peripheral blood samples were obtained individuals...
BACKGROUND To determine the efficacy and safety of 585-nm pulsed dye laser (PDL) in treatment recalcitrant warts children. METHODS AND MATERIAL Retrospective survey medical records children with who were treated PDL between March 1995 through January 1999 at Children's Memorial Hospital outpatient subspecialty center, Chicago, Illinois. RESULTS Sixty-one PDL; 75% them had total clearance after an average 3.1 sessions. Overall success rates 100% for both perineal perianal face-only warts, 93%...
Accurately diagnosing the subtype of epidermolysis bullosa (EB) is critical for management and genetic counselling. Modern laboratory techniques are largely inaccessible in developing countries, where diagnosis remains clinical often inaccurate. To develop a simple diagnostic tool to aid subtyping EB. We developed matrix indicating presence or absence set distinctive features (as rows) nine most prevalent EB subtypes columns). test an individual patient, these was compared with findings...
Our aim was to study the evolution of clinical pattern parthenium dermatitis. Patients with picture consistent dermatitis for 3 years or more along positive patch test were studied. questioned regarding site(s) at onset and change in localization following years. classified into airborne contact dermatitis, chronic actinic (CAD) mixed There 74 patients (49 men 25 women) an age range 22-70 mean duration 7.7 60 (39 21 had 5 9 CAD onset. Of 27 (19 8 changed 11 (6 after average period 4.2 19...
We describe five children with ichthyosis and rickets. The association of rickets is very rare. Four had lamellar one child nonbullous ichthyosiform erythroderma/psoriasis atopy. All biochemical radiological evidence Three clinically evident rickets, whom two severe skeletal deformities. Such a involvement due to in exceptionally suggest that ichthyosis, particular those pigmented skin, need be evaluated for especially developing countries where there background prevalence vitamin D deficiency.
Abstract: Auriculotemporal nerve (Frey) syndrome in children is rare, and may be misdiagnosed as food allergy. Trauma to the auriculotemporal during forceps‐assisted delivery has been implicated about half of reported childhood Frey cases most patients present with unilateral involvement. We describe two Caucasian sisters bilateral syndrome, neither whom was delivered forceps assistance, highlight its distinction from occur a familial pattern, absence history perinatal trauma.
Bleomycin induced flagellate dermatitis is a rare and unique adverse effect. With the declining use of bleomycin, this complication becoming increasingly infrequent in common clinical practice. We herein describe case 22-year-old Indian male with Hodgkin's lymphoma, Ann Arbor stage IIBEX developing following 1(st) cycle chemotherapy ABVD regimen. The diagnostic dilemma illustrative underscores importance awareness prompt identification treatment dermatological toxicity limiting morbidity...
Background Ichthyosiform erythroderma due to keratinizing disorders may suppress cutaneous vitamin D synthesis, leading deficiency and rickets. Objectives To determine the prevalence of rickets in children adolescents with congenital ichthyosis other scaling. Patients methods In this cross‐sectional study, 45 ichthyosiform disorders, 66 controls (group 1: age sex matched, skin diseases than disorders; group 2: healthy volunteers) were included. Evidence was determined clinically (physical...
Kindler syndrome (OMIM 173650) is an autosomal recessive condition characterized by skin blistering, atrophy, photosensitivity, colonic inflammation and mucosal stenosis. Fewer than 100 cases have been described in the literature. First reported 1954, molecular basis of was elucidated 2003 with discovery FERMT1 (KIND1) loss-of-function mutations affected individuals. The gene encodes kindlin-1 (also known as fermitin family homologue 1), a 77 kDa protein that localizes at focal adhesions,...