Luis Trabucco

ORCID: 0000-0003-4118-3504
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About
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Research Areas
  • Advanced Biosensing Techniques and Applications
  • Advanced Polymer Synthesis and Characterization
  • Microfluidic and Capillary Electrophoresis Applications
  • Advanced biosensing and bioanalysis techniques
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Biosensors and Analytical Detection
  • Nanomaterials for catalytic reactions
  • Analytical Chemistry and Sensors
  • Polymer crystallization and properties
  • Photonic Crystals and Applications
  • Mesoporous Materials and Catalysis
  • Polymer Nanocomposites and Properties
  • Iron oxide chemistry and applications

The University of Texas at San Antonio
2022-2024

Drug toxicity assays using conventional 2D static cultures and animal studies have limitations preventing the translation of potential drugs to clinic. The recent development organs-on-a-chip platforms provides promising alternatives for drug toxicity/screening assays. However, most conducted with these only utilize single endpoint results, which do not provide real-time/ near real-time information. Here, a versatile technology is presented that integrates 3D liver-on-a-chip label-free...

10.1002/smll.202403560 article EN Small 2024-08-30

Molecular conformational changes in the collapsing and reswelling processes occurring during phase transition at lower critical solution temperature (LCST) of polymer are not well understood. In this study, we characterized change Poly(oligo(Ethylene Glycol) Methyl Ether Methacrylate)-144 (POEGMA-144) synthesized on silica nanoparticles using Raman spectroscopy zeta potential measurements. Changes distinct peaks associated with oligo(Ethylene (OEG) side chains (1023, 1320, 1499 cm

10.3390/s23125713 article EN cc-by Sensors 2023-06-19

Label-free quantification of polymerization is significant importance in today's research as recent advancements the polymer field have sparked numerous applications biomedical industry. Poly-((Ethylene Glycol) Methyl Ether)- Methacrylate (POEGMA) has been recognized a replacement for PNIPAM due to various factors such biocompatibility and thermal response rate. With rapid response, POEGMA allows variety including potential drug delivery mechanism. In this study, Photonic Crystal-Total...

10.1117/12.2650428 article EN 2023-03-16

Label-Free detection of cardiac biomarkers has become an area great interest with respect to point care (POC) analysis acute myocardial infarction and drug cardiotoxicity assays. DNA aptamers have a potential replacement traditional antibody antigens in bioassays. In comparison antibodies, provide the advantages lower cost, high flexibility, batch-to-batch uniformity, stability at 37°C when immobilized on sensor surface, reusability regeneration solution. However, aptamer usage requires...

10.1117/12.2609898 article EN 2022-03-02
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