A5100439819- Catalytic C–H Functionalization Methods
- Multicomponent Synthesis of Heterocycles
- Sulfur-Based Synthesis Techniques
- Radical Photochemical Reactions
- Synthesis and biological activity
- Chemical Synthesis and Reactions
- Chemical Synthesis and Analysis
- Oxidative Organic Chemistry Reactions
- Synthesis and Catalytic Reactions
- Fluorine in Organic Chemistry
- Cyclopropane Reaction Mechanisms
- Catalytic Cross-Coupling Reactions
- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and Biological Evaluation
- Synthesis of Organic Compounds
- Synthesis of heterocyclic compounds
- Asymmetric Synthesis and Catalysis
- Synthesis of Indole Derivatives
- Forest, Soil, and Plant Ecology in China
- Organoselenium and organotellurium chemistry
- Quinazolinone synthesis and applications
- Ferrocene Chemistry and Applications
- Synthesis of Tetrazole Derivatives
- Catalytic Alkyne Reactions
- Synthetic Organic Chemistry Methods
Zhejiang University of Technology
2015-2025
Xi'an Jiaotong University
2018-2024
China Southern Power Grid (China)
2024
University of Science and Technology of China
2024
Shanghai Institute of Organic Chemistry
2019-2024
National Synchrotron Radiation Laboratory
2024
Foshan University
2024
Anhui University of Technology
2023-2024
Inner Mongolia University of Science and Technology
2024
Weifang People's Hospital
2024
In situ -generated protonated aromatic hydrocarbons overcome their intrinsic electronic properties to serve as catalytic electron acceptors, avoiding the use of photocatalysts, metals, and redox reagents achieve fluoroalkylation.
An efficient multicomponent reaction for the preparation of vinyl sulfone was achieved by hydrogenation/bifunctional sulfonylation alkynyl esters with N- allyl bromodifluoroacetamide, DABSO, and H 2 O under visible-light-only conditions.
Herein, a N-phenylphenothiazine-based hyper-cross-linked polymer (PTH-HCP) was finely designed and constructed, which serves as metal-free heterogeneous photocatalyst for organic transformations. Characterization experiments have shown that this demonstrates outstanding stability, extensive surface area, exceptional photoelectric response properties. Moreover, PTH-HCP showed good catalytic efficiency recyclability in the photochemically driven difluoromethylation/cyclization reactions. This...
An entirely metal-free catalyst system consisting of an easily prepared recyclable new TEMPO derived sulfonic salt catalyst, and mineral acids (NaNO2 HCl) has been developed for selective aerobic oxidation structurally diverse benzylic sp3 C–H bonds ethers alkylarenes. The mild reaction conditions allow the generation synthetically biologically valued isochromanones xanthones from readily accessible alkyl aromatic precursors in good yields.
Abstract An efficient visible‐light‐induced (thio)etherification of quinoxalin‐2(1H)‐ones with divergent aliphatic alcohols and thiols (primary, secondary, tertiary) at room temperature in air has been developed. This protocol was highlighted by its mild conditions, readily available starting materials, operational simplicity, wide functional group tolerance. magnified image
An electrochemical method for the C(sp2)–H thioetherification of quinoxalin-2(1H)-ones with primary, secondary, and tertiary thiols has been reported. Various underwent this smoothly under metal- chemical oxidant-free conditions, affording 3-alkylthiol-substituted in moderate to good yields.
A proof-of-concept methodology for addressing small amounts of chemical data using transfer learning is presented. We demonstrate this by applying combined with the transformer model to small-dataset Heck reaction prediction. Introducing significantly improved accuracy transformer-transfer (94.9%) over that transformer-baseline (66.3%).
We consider retrosynthesis to be a machine translation problem. Accordingly, we apply an attention-based and completely data-driven model named Tensor2Tensor data set comprising approximately 50 000 diverse reactions extracted from the United States patent literature. The significantly outperforms seq2seq (37.4%), with top-1 accuracy reaching 54.1%. also offer novel insight into causes of grammatically invalid SMILES, conduct test in which experienced chemists select analyze "wrong"...
A K 2 S O 8 -catalyzed versatile C(sp )–C(sp 3 ) bond formation with N-heteroaromatics and γ-lactams/amides in H high regioselectivity was developed.
A practical and scalable protocol for electrochemical arylation of quinoxalin(on)es with arylhydrazine hydrochlorides under mild conditions has been developed. This method exhibits high efficiency, easy scalability, broad functional group tolerance. Various arylhydrazines underwent this transformation smoothly in an undivided cell, providing the corresponding aryl-substituted moderate to good yields. radical mechanism is involved reaction.
Abstract The generation of alkyl radical from C(sp 3 )−H substrates via hydrogen atom abstraction represents a desirable yet underexplored strategy in alkylation reaction since involving common concerns remain adequately unaddressed, such as the harsh conditions, limited substrate scope, and employment noble metal- or photo-catalysts stoichiometric oxidants. Here, we utilize synergistic photoredox transfer (HAT) catalysis to accomplish general practical functionalization unactived centers...
A π-conjugated small molecule-oxygen charge transfer state enables selective C(sp 3 )–H oxidation, avoiding the use of photocatalysts, metals, and redox reagents.
A highly efficient electrochemically dehydrogenative C–H/O–H cross‐coupling between quinoxalin‐2(1 H )‐ones and alcohols was developed under mild conditions. Using different types of as solvent, various 3‐alkoxylated were synthesized in a simple undivided cell at room temperature. This novel electrochemical cross‐dehydrogenative coupling approach features broad functional group tolerance, metal‐ oxidant‐free conditions, moderate to good yields.
Visible light-driven self-catalyzed regulable alkylation of 2 H -benzothiazoles with diverse aliphatic C–H donors via the combination HAT and self-photoredox catalysis.
The Vilsmeier (or Vilsmeier-Haack) reaction has historically been a topic of great interest to organic chemists, and it continues attract considerable attention. Since its discovery in 1927, 1 i...
A metal-free catalytic strategy for the facile synthesis of biologically relevant molecular architectures indolizines and imidazopyridines has been developed. The process is promoted by amine N-heterocyclic carbene (NHC) relay catalysis via Michael addition-[3 + 2] fusion simple azaarenes α,β-unsaturated aldehydes. preparative power demonstrated in anxiolytic drug saripidem two one-pot operations with overall 45% yield.