Akira Watanabe

ORCID: 0000-0003-4127-0018
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About
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Research Areas
  • Particle physics theoretical and experimental studies
  • Quantum Chromodynamics and Particle Interactions
  • Black Holes and Theoretical Physics
  • Textile materials and evaluations
  • Neuroscience and Neural Engineering
  • Photoreceptor and optogenetics research
  • Lipid Membrane Structure and Behavior
  • Neurobiology and Insect Physiology Research
  • Intracranial Aneurysms: Treatment and Complications
  • Vascular Malformations Diagnosis and Treatment
  • High-Energy Particle Collisions Research
  • Neurosurgical Procedures and Complications
  • Visual perception and processing mechanisms
  • Meningioma and schwannoma management
  • Neural dynamics and brain function
  • Cerebrospinal fluid and hydrocephalus
  • Neuroscience and Neuropharmacology Research
  • Glioma Diagnosis and Treatment
  • Advanced Vision and Imaging
  • Cephalopods and Marine Biology
  • Color Science and Applications
  • Mechanical Behavior of Composites
  • Head and Neck Surgical Oncology
  • Mitochondrial Function and Pathology
  • Structural Analysis and Optimization

Tokushima University
2016-2024

Tokyo Dental College
2024

University of South China
2023-2024

China Three Gorges University
2022-2023

National Institute of Health Sciences
2022

Kindai University
2005-2021

Gunma University Hospital
2021

Institute of High Energy Physics
2018-2020

Chinese Academy of Sciences
2018-2020

University of Chinese Academy of Sciences
2018-2020

Membrane transporters that use energy stored in sodium gradients to drive nutrients into cells constitute a major class of proteins. We report the crystal structure member solute symporters (SSS), Vibrio parahaemolyticus sodium/galactose symporter (vSGLT). The ∼3.0 angstrom contains 14 transmembrane (TM) helices an inward-facing conformation with core inverted repeats 5 TM (TM2 TM6 and TM7 TM11). Galactose is bound center core, occluded from outside solutions by hydrophobic residues....

10.1126/science.1160406 article EN Science 2008-07-04

Various types of light sources were used during the course present experiments; an Osram quartz-iodine lamp operated at d-c 15 volts and approximately 150 watts was in later staage study as a source near-visible ultraviolet light. Quartz lenses L1 L2 (Fig. 1) to condense on 1-3-mm portion nerve. Optical filter F1, absorb visible light, either Corning glass (CS 7-83) or Bausch Lomb interference for 365 m,. Visible emitted by nerve detected with photomultiplier tube (RCA 4463) right angle...

10.1073/pnas.61.3.883 article EN public-domain Proceedings of the National Academy of Sciences 1968-11-01

Transmission across the septal junctions of segmented giant axons crayfish is accounted for quantitatively by a simple equivalent circuit. The membranes are passive, resistive components and transmission ephaptic, electrotonic spread action current pre-septal spike. appears as potential, considerably smaller than spike, but usually still large enough to initiate new spike in post-septal segments. do not exhibit rectification, at least over range +/- 25 mv polarization this accounts their...

10.1085/jgp.45.2.267 article EN The Journal of General Physiology 1961-11-01

ABSTRACT A South American gymnotid Eigenmannia, changes the discharge frequency of its electric organ when a weak signal is applied to it with very close that own discharge. Otherwise, extremely constant at fixed temperature. When higher or lower than fish discharge, response decrease increase frequency, respectively. two frequencies are exactly same, fails occur. The threshold this low. In one was about 3 μV./cm.

10.1242/jeb.40.1.57 article EN Journal of Experimental Biology 1963-03-01

1. The potential changes were recorded from the individual large cells of lobster cardiac ganglion with aid intra-cellular microelectrodes. Special attention was paid to interaction among cells, and, using a dual beam oscilloscope, simultaneous recording made two different cells.2. "follower" type most common and similar that obtained in an American lobster, described by Hagiwara Bullock (10), Terzuolo (7).3. synaptic potentials adjacent closely synchronized. This seems indicate existence...

10.2170/jjphysiol.8.305 article EN The Japanese Journal of Physiology 1958-01-01

Humans become increasingly fragile as they age. We show that something similar may happen to states, although for the risk of termination levels off grow older, allowing some persist millennia. Proximate causes their ...How states and great powers rise fall is an intriguing enigma human history. Are there any patterns? Do polities more vulnerable over time age? analyze longevity in hundreds premodern using survival analysis help ...

10.1073/pnas.48.7.1177 article EN Proceedings of the National Academy of Sciences 1962-07-01

Spontaneous intracranial hypotension (SIH) presents with orthostatic headache, and the diagnosis is made on basis of low CSF pressure brain MR imaging findings characteristic disorder. However, a broad spectrum symptoms SIH recognized, some cases have no typical abnormalities. believed to be caused by leakage from spinal dural sac, whereas usefulness spine remains unclear. Our aim was elucidate diagnostic value imagingThe sensitivities for detection were retrospectively evaluated in 18...

10.3174/ajnr.a1277 article EN cc-by American Journal of Neuroradiology 2008-09-03

10.1152/ajplegacy.1967.213.6.1465 article EN American Journal of Physiology-Legacy Content 1967-12-01

10.1002/jcp.1030470308 article EN Journal of Cellular and Comparative Physiology 1956-06-01

From somata of the pacemaker neurons in Squilla heart ganglion, potentials for spontaneous periodic burst discharge are recorded with intracellular electrodes. The electrical activity is composed slow and superimposed spikes, divided into four types, which are: (a) "mammalian heart" type, (b) "slow generator" (c) grower" (d) deficient" type. Since axons far from do not produce potentials, soma dendrites must be where generated. Hyperpolarization impedes generation potential, showing that it...

10.1085/jgp.50.4.839 article EN The Journal of General Physiology 1967-03-01

Novel APOBEC1 target 1 (Nat1) (also known as "p97," "Dap5," and "Eif4g2") is a ubiquitously expressed cytoplasmic protein that homologous to the C-terminal two thirds of eukaryotic translation initiation factor 4G (Eif4g1). We previously showed Nat1-null mouse embryonic stem cells (mES cells) are resistant differentiation. In current study, we found NAT1 eIF4G1 share many binding proteins, such factors eIF3 eIF4A ribosomal proteins. However, did not bind eIF4E or poly(A)-binding which...

10.1073/pnas.1617234114 article EN Proceedings of the National Academy of Sciences 2016-12-21

A direct demonstration is given of interaction between specific neurons without impulses, via graded slow potentials electrotonically spread from one cell to another. Repetitive polarizing or depolarizing current pulses 50 200 msec. and subthreshold intensity were passed through an intracellular electrode in the soma a follower isolated ganglion. When frequency near natural rhythm impulse bursts corresponding heart beats arising pacemaker 5 10 mm. posteriorly, rapidly become synchronized...

10.1085/jgp.43.6.1031 article EN The Journal of General Physiology 1960-07-01

The effect of tetrodotoxin on excitability internally perfused squid giant axons immersed in various sodium-free media was examined. Action potentials were found to be suppressed by this substance, with or without sodium ion the external medium. Tetrodotoxin showed a strong suppressive upon action produced containing salts only divalent cations (CaCl 2 , CaBr SrCl BaCl ). Our findings concerning do not support separate-channel hypothesis for excitable membranes.

10.1126/science.155.3758.95 article EN Science 1967-01-06

Nerves from spider crabs and squid fluoresce when stained with Acridine Orange. The intensity of fluorescence increases during nerve conduction. Prolongation the electric response in axon is associated a change similar duration. These findings suggest that physicochemical properties macromolecules around dye molecules membrane drastically process

10.1126/science.163.3868.683 article EN Science 1969-02-14

NERVES STAINED WITH ONE OF THE FOLLOWING FLUOROCHROMES WERE FOUND TO RESPOND ELECTRIC STIMULATION TRANSIENT CHANGES IN FLUORESCENT LIGHT: acridine orange, yellow, 8-anilinonaphthalene-1-sulfonate, auramine O, 1-dimethylaminonaphthalene-5-sulfonyl chloride, fluorescein isothiocyanate, LSD, pyronin B, Y, rhodamine G, rose bengal, and 2-toluidinylnaphthalene sulfonate. The properties of covalently bonded fluorochromes in the nerve behavior introduced into axon interior were studied. By...

10.1073/pnas.64.4.1362 article EN Proceedings of the National Academy of Sciences 1969-12-01

Laser ablation MC-ICP-MS allows in situ strontium isotope data to be obtained for incrementally formed bioapatites such as enamel with extremely high spatial resolution. Here, we provide a large-scale application of the method comparing ...Understanding mobility and landscape use is important reconstructing subsistence behavior, range, group size, it may contribute our understanding phenomena dynamics biological cultural interactions between distinct ...

10.1073/pnas.54.3.763 article EN Proceedings of the National Academy of Sciences 1965-09-01

Synchronously dividing cell cultures of Catharanthus roseus were used to isolate cDNAs for two mitotic cyclins, named CYS and CYM. The deduced protein sequence is similar that A‐type CYM belongs the group B‐type cyclins. In a fashion pattern expression seen cyclins in mammalian cells, expressed before C. cells during cycle. mRNA accumulated at onset S phase disappeared early G2 phase, whereas was detected M phases Tobacco homologs genes showed cell‐cycle dependent patterns synchronous...

10.1046/j.1365-313x.1997.11050983.x article EN The Plant Journal 1997-05-01
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