A5011812393- Veterinary Oncology Research
- Veterinary Orthopedics and Neurology
- Tracheal and airway disorders
- Tumors and Oncological Cases
- Infectious Diseases and Mycology
- Urological Disorders and Treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Veterinary Equine Medical Research
- Sarcoma Diagnosis and Treatment
- Cardiovascular Conditions and Treatments
- Tendon Structure and Treatment
- Shoulder Injury and Treatment
- Veterinary Medicine and Surgery
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Calcium signaling and nucleotide metabolism
- Nasal Surgery and Airway Studies
- Vascular Malformations and Hemangiomas
- Ureteral procedures and complications
- Blood Coagulation and Thrombosis Mechanisms
- Herpesvirus Infections and Treatments
- Hemophilia Treatment and Research
- Cardiac Arrhythmias and Treatments
- Blood transfusion and management
- Heparin-Induced Thrombocytopenia and Thrombosis
- Gynecological conditions and treatments
Royal Veterinary College
2014-2024
University College London
2020
University of London
2020
Royal Brompton Hospital
1997
University of California, San Diego
1976
Lipomas are masses of mesenchymal origin, comprising adipocytes, and often clinically unremarkable but can be alarming to owners. Although lipomas reportedly common in dogs, no studies have specifically investigated risk factors associated with their occurrence. This study was a large-scale retrospective analysis electronic patient records dogs attending practices participating VetCompass™. Univariable multivariable logistic regression methods were used evaluate associations between...
Abstract Background Osteosarcoma is a malignant bone neoplasia that has high welfare consequences for affected dogs. Awareness of breed and canine conformational risk factors osteosarcoma can assist with earlier diagnosis improved clinical management. Study in dogs also offers translational value humans. Anonymised data within VetCompass on under primary veterinary care the UK were searched cases. Descriptive statistics reported overall breed-specific prevalence. Risk factor analysis used...
Objectives To assess the breed‐specific prevalence of, and effects of corrective airway surgery on, gastrointestinal signs in French bulldogs, English bulldogs pugs presenting with brachycephalic syndrome to a referral teaching hospital. Materials Methods In this retrospective study, ptyalism, regurgitation vomiting were graded at presentation using previously established scoring system. Staphylectomy nares resection performed on all dogs. Gastrointestinal re‐assessed via telephone follow‐up...
Summary We evaluated the effectiveness, ease of use and safety five machines for blood salvage during coronary artery surgery. All were equally effective in concentrating red cells. measured haemoglobin, packed cell volume, free white cells, neutrophil elastase, platelets, thrombin–antithrombin complex (TAT), prothrombin activation peptide F 1·2 , fibrin degradation product (d‐dimers), tissue plasminogen activator (tPA) heparin wound blood, washed suspensions a unit bank prepared each...
To describe the diagnostic tests used and their comparative performance in dogs diagnosed with sinonasal aspergillosis United Kingdom. A secondary objective was to signalment, clinical findings common clinicopathologic abnormalities aspergillosis.
The objective was to review surgical techniques and postoperative complications of correction for patellar luxation (PL) in cats. A retrospective study evaluating 85 surgeries 71 cats performed. records from four referral centres were searched with management PL. Signalment, history, PL grade direction, corrective outcome retrieved. Binary logistic regression analysis used interrogate relationships between case features, methods outcomes. outcomes classified as minor major (requiring...
We describe a novel surgical technique used to correct feline patellar luxation (PL) where abnormal tracking persists despite conventional corrective surgery. An anatomical difference between and canine stifles is that the patella wider relative trochlear sulcus. This results in less constrained tracking. Therefore, subluxation common normal cats. It was noticed some cases with clinically significant PL, PL persisted intraoperatively performing standard procedures. report - partial...
The aims of this observational, analytical, retrospective study were to (i) obtain computed tomographic (CT) cricoid dimensions (height, width, and transverse-sectional area), (ii) compare the between brachycephalic mesaticephalic breeds, (iii) cartilage dogs without affected with airway syndrome. is important help further evaluate understand anatomical components Measurements performed in 147 59 dogs. was found be significantly more oval Pugs French Bulldogs compared breeds. area smallest...
The objectives of this study were to: (1) document the incidence surgical site dehiscence after full-thickness gastrointestinal biopsy in dogs and cats (2) identify potential risk factors.Data relating to undergoing reviewed retrospectively following submission a completed questionnaire by 12 referral institutions. Outcome measures definite dehiscence, possible (clinical records suggestive but not confirmed), suspected (definite combined) death within 14 days. Logistic regression was planned...
Certain postoperative wounds are recognised to be associated with more complications than others and may termed high-risk. Wound healing can particularly challenging following high-energy trauma where wound necrosis infection rates high. Surgical incision for joint arthrodesis also considered high-risk as it requires extensive invasive surgery distal limb swelling dehiscence common. Recent human literature has investigated the use of negative pressure therapy (NPWT) over closed surgical...
Summary A 66 year old male, referred for cardiac surgery, was found to have high molecular weight kininogen deficiency (activity <1%). Apart from activated partial thromboplastin time (APTT) >300 s, tests of haemostasis were otherwise normal (factors VIII, IX, XI, XII and prekallikrein). No inhibitor coagulation found. The (ACT) 800 s pre-operatively >1000 after heparin. Heparin levels measured directly by an anti-Xa chromogenic assay, with values between 2.9 3.2 u/ml during...
Male and female rabbits were treated with 17beta-oestradiol during the 9-week development of a contracture in left hind limb. The right limb served as paired control. Untreated (absolute control) animals received saline injections. After 9 weeks biochemical analyses water, hexosamine, soluble total collagen, well biomechanical measurements joint stiffness, performed on dissected knees. In all cases reduced measured stiffness contractures by approximately 50% compared to untreated animals....
Intrathoracic extracardiac hemangiosarcoma (HSA) is rare in dogs. This report describes three dogs with acute onset dyspnea due to hemorrhagic pleural effusion resulting from intrathoracic masses, which were confirmed as HSA by histopathology. The stabilized thoracocentesis and intravascular fluid resuscitation. Computed tomography identified not originating the heart or pulmonary parenchyma. Surgical exploration was performed all cases. Case 1 euthanized intraoperatively tumor could be...
Abstract Objective To determine the influence of extreme brachycephalic conformation on presenting signs, imaging findings, intraoperative and perioperative complications following total ear canal ablation lateral bulla osteotomy (TECA‐LBO). Study design Cross‐sectional retrospective study. Animals A 306 ( n = 242 dogs) TECA‐LBOs (extreme breeds [EBB] 81, other [OB] 225). Methods Medical records patients undergoing TECA‐LBO at a single referral institution (2010–2022) were evaluated. Results...
Distinguishing bacterial cystitis from subclinical bacteriuria is necessary for feline treatment protocols and antimicrobial stewardship. This can be challenging in cats with subcutaneous ureteral bypass (SUB) systems because they may present lower urinary tract signs without bacteriuria. We investigated the relationship between positive urine culture SUBs, including factors associated each.
Abstract Objective The aim of this study was to assess computed tomography (CT) images cadaveric feline stifles and record the relationship between patella femoral trochlea in normal stifles; then investigate effect block recession trochleoplasty (BRT) with without partial parasagittal patellectomy (PPP) on patellofemoral contact, depth patellar size patella. Materials Methods sample population included six cat cadavers (12 stifles). Preoperative CT scans three positions: extended...
An 11-year-old cat was referred following vehicular trauma for evaluation and treatment of right thoracic limb lameness which non-responsive to conservative management. Gait assessment revealed a severe weight-bearing lameness, soft tissue swelling over the dorsal border scapula, crepitus upon direct palpation scapula lateralisation adduction distal allowing diagnosis scapular avulsion be made. Computed tomography (CT) demonstrated comminuted fracture tear serratus ventralis muscle. The...
Objectives To describe the outcome and complications associated with use of caudal superficial epigastric axial pattern flaps in dogs cats. Material Methods Multicentre retrospective review descriptive study clinical records cats having undergone between 2007 2020. Data retrieved included signalment, aetiology surgical defect, tumour type, presence/absence clean margins, post‐operative wound infection, peri‐ antibiotics, duration anaesthesia, surgery, presence hypothermia, hypotension, drain...
Anal sac disease (ASD) can be divided into two main categories: inflammation and neoplasia. It is relatively common in dogs, with the inflammatory form having a reported prevalence of 12.5 per cent. Cases ASD present signs perineal pruritus such as licking, scooting tail base discomfort, well dyschezia tenesmus. This article discusses most anal conditions seen veterinary practice, describes how they managed, both medically surgically.
Lipomas are relatively common and biologically benign masses of mesenchymal origin consisting adipocytes. This study reports benchmark data on the clinical management outcomes lipomas in dogs under UK primary veterinary care. The used a cross-sectional analysis cohort from that were care at practices participating within VetCompass January 1, 2013 to December 31, 2013. Descriptive analytic statistics characterised following presumptive lipoma diagnosis. included 2765 cases 384 284 during...
A kitten presented with acute kidney injury, bilateral hydronephrosis and proximal hydroureter, three days following ureteral ligation, during a complicated ovariohysterectomy procedure. Clinical signs were anorexia, lethargy, weakness, hypothermia, nausea, pain anuria, associated marked azotaemia, hyperkalaemia metabolic acidosis. Insufficient response to medical management alone led emergency surgical placement of subcutaneous bypass (SUB) systems, resulting in dramatic improvement...