A5101492618- Helicobacter pylori-related gastroenterology studies
- Gastric Cancer Management and Outcomes
- Radiomics and Machine Learning in Medical Imaging
- Colorectal Cancer Surgical Treatments
- Anorectal Disease Treatments and Outcomes
- Lymphoma Diagnosis and Treatment
- CAR-T cell therapy research
- Lymphadenopathy Diagnosis and Analysis
- Infectious Diseases and Tuberculosis
- Thyroid Cancer Diagnosis and Treatment
- Gastrointestinal disorders and treatments
- Hematological disorders and diagnostics
- Colorectal and Anal Carcinomas
- Bone and Joint Diseases
- Peptidase Inhibition and Analysis
- Oral and Maxillofacial Pathology
- Eosinophilic Esophagitis
- Medical Imaging Techniques and Applications
- Lung Cancer Diagnosis and Treatment
- Advanced X-ray and CT Imaging
- Prostate Cancer Treatment and Research
- Radiation Dose and Imaging
- Soft tissue tumors and treatment
- Renin-Angiotensin System Studies
- Cerebrovascular and genetic disorders
First Affiliated Hospital Zhejiang University
2008-2024
Zhejiang University
2012-2024
Guiyang Medical University
2023
Soochow University
2016-2022
Second Affiliated Hospital of Soochow University
2016-2022
Harbin Medical University
2022
Second Affiliated Hospital of Harbin Medical University
2022
Jilin Medical University
2021
Jilin University
2021
Affiliated Hospital of Zunyi Medical College
1996-2020
Abstract Recently, chimeric antigen receptor (CAR)-T cell therapy has shown great promise in treating haematological malignancies 1–7 . However, CAR-T currently several limitations 8–12 Here we successfully developed a two-in-one approach to generate non-viral, gene-specific targeted cells through CRISPR–Cas9. Using the optimized protocol, demonstrated feasibility preclinical study by inserting an anti-CD19 CAR cassette into AAVS1 safe-harbour locus. Furthermore, innovative type of with PD1...
The objectives of this study were to evaluate the diagnostic accuracy fluorodeoxyglucose (FDG)-PET and FDG-PET/computed tomography (CT) in detection primary tumors patients presenting with carcinoma unknown (CUP) unidentified by conventional workup, compare statistical difference between FDG-PET FDG-PET/CT. Twenty-eight studies (involving a total 910 patients) published 1990 2007 reviewed. These evaluated role FDG-PET/CT after physical examination workup failed detect tumor. Systematic...
PET is a popular medical imaging modality for various clinical applications, including diagnosis and image-guided radiation therapy. The low-dose (LDPET) at minimized dosage highly desirable in clinic since involves ionizing radiation, raises concerns about the risk of exposure. However, reduced dose radioactive tracers could impact image quality diagnosis. In this paper, supervised deep learning approach with generative adversarial network (GAN) cycle-consistency loss, Wasserstein distance...
Abstract Background Gastric tuberculosis mimicking submucosal tumors is extremely rare and often misdiagnosed. Case presentation Three cases of gastric were identified among patients admitted to local county hospitals because upper abdominal discomfort pain, with gastroscopy showing tumors. The our hospital for endoscopic ultrasonography (EUS). As EUS revealed evidence the first two patients, we considered tuberculosis. However, atypical characteristics miniature ultrasonic probe EUS, lesion...
To identify clinical and neuroimaging characteristics between posterior cortical atrophy (PCA) typical amnestic Alzheimer's disease (tAD) patients at an early stage, 16 PCA 13 age-matched tAD were enrolled. Compared with patients, showed higher mean recognition recall test scores, lower calculation, spatial attention, shape discrimination, writing scores. Mean right hippocampal volume was larger in compared while gray matter (GM) of bilateral parietal occipital lobes smaller patients....
The present study describes the first reported case of a sinonasal inverted papilloma (IP) with squamous cell carcinoma (SCC) that presented as cancer unknown primary in English-language literature. In July 2010, 66-year old male 6-month history painless, progressive mass right submandibular region. Physical examination revealed 3×4-cm smooth, non-tender and subsequently, excision gland was performed. Post-operative pathological indicated poorly-differentiated SCC lymph node....
Tumour markers producing primary adenocarcinoma of upper urinary tract is extremely rare. We report a case advanced renal pelvis and ureter with highly elevated serum levels alpha-fetoprotein (AFP) carbohydrate antigen 19-9 (CA19-9). This 66-year-old man was diagnosed left pelvic ureteral tumours para-aortic lymph node swelling, no evidence abnormality in his digestive or reproductive system. He successfully treated nephroureterectomy dissection followed by gemcitabine/carboplatin...
Background.During minimally invasive spine surgery, nerve root decompression is challenging due to the anatomical division and uncertainty in lumbar lateral recess (LLR).Objectives.To evaluate outcome safety of foraminoplasty using percutaneous transforaminal endoscopic (PTED) (performed with an aid a trephine) treatment stenosis (LLRS). Materials methods.All operations were performed under local anesthesia prone position.The puncture point was 10-14 cm away from midline spinous process.One...
The aetiology of oral squamous cell carcinoma (OSCC) remains unclear. Numerous single nucleotide polymorphisms (SNPs) associated with cancer have been identified using genome‑wide association studies (GWAS). present study was designed to identify common SNPs susceptibility and evaluate their involvement in OSCC. Susceptible loci were by analysing a GWAS catalogue. A multicentre case‑control an OSCC control population performed for selected SNPs. function the locus its gene explored reverse...
Lymphangioma of the esophagus is an exceedingly rare submucosal benign tumor [1]. Only 23 cases have been reported since 1934, and most tumors are smaller than 2 cm in diameter. Herein, we present first report a giant esophageal lymphangioma (16 × 6 4 cm), which was completely safely resected by endoscopic dissection (ESD).