Juliana Botero

ORCID: 0000-0003-4132-4282
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About
Contact & Profiles
Research Areas
  • Advanced biosensing and bioanalysis techniques
  • Total Knee Arthroplasty Outcomes
  • Vibrio bacteria research studies
  • Cancer Cells and Metastasis
  • Orthopedic Infections and Treatments
  • Cancer, Hypoxia, and Metabolism
  • Salmonella and Campylobacter epidemiology
  • CRISPR and Genetic Engineering
  • Orthopaedic implants and arthroplasty
  • RNA and protein synthesis mechanisms
  • Biosensors and Analytical Detection
  • Cancer Research and Treatments
  • Bacteriophages and microbial interactions

University of the Basque Country
2021

Policlínica Gipuzkoa
2021

Universidad de Antioquia
2016

Breast cancer is one of the most common pathologies diagnosed in clinical practice. Despite major advancements diagnostic approaches, there no widely accepted biomarker practice that can diagnose breast malignancy. Confirmatory diagnosis still relies on pathological assessment tissue biopsies by expert pathologists. Thus, an unmet need for new types biomarkers and novel platform technologies be easily robustly integrated into clinic assist Herein, we show nuclease activity associated to...

10.3390/cancers13020276 article EN Cancers 2021-01-13

An undecamer oligonucleotide probe based on a pair of deoxythymidines flanked by several modified nucleotides is specific and highly efficient biosensor for micrococcal nuclease (MNase), an endonuclease produced Staphylococcus aureus. Herein, the interaction mode cleavage process such probes are identified described first time. Also, we designed truncated pentamer as minimum-length substrates required biosensing. By means computational (virtual docking) experimental (ultra-performance liquid...

10.1021/acs.jmedchem.1c00884 article EN cc-by Journal of Medicinal Chemistry 2021-08-30
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