A5052775093- Advanced Chemical Sensor Technologies
- Gas Sensing Nanomaterials and Sensors
- Mechanical and Optical Resonators
- Analytical Chemistry and Sensors
- Fullerene Chemistry and Applications
- Force Microscopy Techniques and Applications
- Insect Pheromone Research and Control
- Advanced MEMS and NEMS Technologies
- Advanced biosensing and bioanalysis techniques
- Carbon Nanotubes in Composites
- Graphene and Nanomaterials Applications
- Acoustic Wave Resonator Technologies
- Olfactory and Sensory Function Studies
- Advanced Sensor and Energy Harvesting Materials
- Graphene research and applications
- Concrete and Cement Materials Research
- Metal-Organic Frameworks: Synthesis and Applications
- RNA Interference and Gene Delivery
- 3D Printing in Biomedical Research
- Analytical Chemistry and Chromatography
- Cellular Mechanics and Interactions
- Molecular Junctions and Nanostructures
- Grouting, Rheology, and Soil Mechanics
- Innovative concrete reinforcement materials
- Advanced Materials and Mechanics
National Institute for Materials Science
2016-2025
Gifu University
2024
Ōtani University
2024
The University of Tokyo
1997-2018
Ibaraki University
2018
University of Tsukuba
2016
SPring-8
2014
University of Hyogo
2014
Tokyo Medical and Dental University
2013
Tokyo University of Science
2008
Porphyrins and related families of molecules are important organic modules as has been reflected in the award Nobel Prizes Chemistry 1915, 1930, 1961, 1962, 1965, 1988 for work on porphyrin-related biological functionalities. The porphyrin core can be synthetically modified by introduction various functional groups other elements, allowing creation numerous types derivatives. This feature makes porphyrins extremely useful especially combination with their interesting photonic, electronic...
We report the preparation of hierarchically structured fullerene C70 cubes (HFC) composed mesoporous nanorods with crystalline pore walls. Highly cubic shape crystals (FC) were grown at a liquid–liquid interface formed between tert-butyl alcohol and solution in mesitylene. HFCs then prepared by washing isopropanol FC 25 °C. The growth directions diameters could be controlled varying conditions. perform as an excellent sensing system for vapor-phase aromatic solvents due to their easy...
Dimensionally mixed ternary nanocomposite RGO/CNT/CeO<sub>2</sub>develops novel functions displaying enhanced electrochemical performance.
A highly aligned 1D fullerene whisker (FW) scaffold in a centimeter area is fabricated by interfacial alignment. The resulting FW enables concurrent control over cellular orientation and differentiation to muscle cells. This made facile method, hence the substrate promising alternative other cell scaffolds for tissue engineering. As service our authors readers, this journal provides supporting information supplied authors. Such materials are peer reviewed may be re-organized online delivery,...
A versatile method for the rapid fabrication of aligned fullerene C60 nanowhiskers (C60NWs) at air-water interface is presented. This based on vortex motion a subphase (water), which directs floating C60NWs to align water surface according direction rotational flow. Aligned could be transferred onto many different flat substrates, and, in this case, glass substrates were employed as scaffold cell culture. Bone forming human osteoblast MG63 cells adhered well C60NWs, and their growth was...
There is a growing interest in the development of dynamic adaptive biomaterials for regulation cellular functions. However, existing materials are limited to two-state switching presentation and removal cell-adhesive bioactive motifs that cannot emulate native extracellular matrix (ECM) vivo with continuously adjustable characteristics. Here, tunable composed protein monolayer assembled at liquid-liquid interface demonstrated, which adapt dynamically cell traction forces. An ultrastructure...
Supramolecular assembly can be used to construct a wide variety of ordered structures by exploiting the cumulative effects multiple noncovalent interactions. However, construction anisotropic nanostructures remains subject some limitations. Here, we demonstrate preparation fullerene-based supramolecular differentiation, which is programmed control strategies. We have carefully combined interfacial and local phase separation phenomena. Two fullerene derivatives, PhH C12H, were together formed...
In sharp contrast to conventional solid/hydrogel platforms, water-immiscible liquids, such as perfluorocarbons and silicones, allow the adhesion of mammalian cells via protein nanolayers (PNLs) formed at interface. However, fluorocarbons which are typically used for liquid cell culture, possess only narrow ranges physicochemical parameters have not allowed a wide variety culturing environments. this paper, it is proposed that ionic liquids (ILs) new family substrates with tunable properties...
1D polymerization of a DNA origami structure at the 2D air–water interface has been successfully regulated by Langmuir–Blodgett technique.
We report production of highly crystalline fullerene C70 cubes possessing an open-hole structure at the center each their faces using a solution-based self-assembly strategy. The holes are isolated with solid core interiors cubes. can be intentionally closed by introducing additional and reopened applying electron beam irradiation. exhibit preferential recognition graphitic carbon particles over polymeric resin similar dimensions due to cubes' sp2-rich carboniferous nature.
Abstract Mechanical cues of cellular microenvironments can modulate cell functions including spreading and differentiation. Most studies are performed using a solid substrate, it is thought that cells cannot spread on fluid substrates because rapid relaxation, which resist against actomyosin‐based contractility. Here, the growth anchorage‐dependent such as human mesenchymal stem at liquid interface between perfluorocarbon culture medium observed. It demonstrated monomolecular protein...
Abstract The efficient treatment of lung diseases requires lung-selective delivery agents to the lung. However, is difficult because accumulation micrometer-sized carriers in often induces inflammation and embolization-related toxicity. Here we demonstrate a system small interfering RNA (siRNA) by controlling size carrier vehicle blood vessels. made tetra(piperazino)fullerene epoxide (TPFE), water-soluble cationic tetraamino fullerene. TPFE siRNA form sub-micrometer-sized complexes buffered...
There is growing evidence to suggest that the prevailing physical microenvironment and mechanical stress regulate cellular functions, including adhesion, proliferation, differentiation. Moreover, determines stem-cell lineage depending on stiffness of substrate relative biological tissues as well relaxation properties viscoelastic substrates used for cell culture. However, there little known regarding effects a fluid substrate, where essentially absent. Here, we demonstrate regulation...
The molecular conformation of a bisbinaphthyldurene (BBD) molecule is manipulated using low-temperature ultrahigh-vacuum scanning tunneling microscope (LT-UHV STM) on an Au(111) surface. BBD has two binaphthyl groups at both ends connected to central durene leading anti/syn/flat conformers. In solution, dynamic nuclear magnetic resonance indicated the fast interexchange between anti and syn conformers as confirmed by density functional theory calculations. After deposition in submonolayer...
Development of human mesenchymal stem cell (hMSC)-based therapies is hindered by the limited availability adult cells. Long-term retention multipotency and stem-like phenotypes remains a key challenge in large-scale vitro expansion process. In this paper, we report primary example use highly aligned fullerene nanowhisker nanopatterned scaffolds to regulate precisely adhesion function hMSCs. Continuously tunable alignment nanowhiskers was attained using simple Langmuir–Blodgett approach. We...
Abstract We have developed nanometer-flat deoxyribonucleic acid (DNA)-featured solid thin films using a DNA source extracted from salmon sperm via laser molecular beam deposition (LMBD) under high-vacuum condition. The formed by LMBD had flatness with an average surface roughness of 7.4 nm. Although fragmentation due to the cleavage phosphate bonds was observed, quartz crystal microbalance (QCM) sensors fabricated showed higher methanol detection capability than spin coating, indicating that...
A sensing signal obtained by measuring an odor usually contains varied information that reflects origin of the itself, while effective approach is required to reasonably analyze informative data derive desired information. Herein, we demonstrate quantitative analysis was achieved through systematic material design-based nanomechanical combined with machine learning. ternary mixture consisting water, ethanol, and methanol selected as a model system where target molecule coexists structurally...
Abstract Nanomachine and molecular machines are state-of-the-art objects in current physics chemistry. The operation manufacturing of nanosize top-level technologies that we have desired to accomplish for a long time. There been extensive attempts design synthesize nanomachines. In this paper, review the these using concept nanoarchitectonics toward design, synthesis, testing machinery, especially at interfacial media. first half review, various historical prepare nanomachines introduced as...