A5084336811- Fungal Biology and Applications
- Microbial Natural Products and Biosynthesis
- Various Chemistry Research Topics
- Memory Processes and Influences
- Analytical Chemistry and Chromatography
- Experimental Learning in Engineering
- Problem and Project Based Learning
- Sesquiterpenes and Asteraceae Studies
- Innovative Teaching and Learning Methods
- Plant and fungal interactions
- Student Assessment and Feedback
- Molecular spectroscopy and chirality
- Scientific Computing and Data Management
- Evaluation of Teaching Practices
- Artificial Intelligence in Healthcare and Education
- Machine Learning in Materials Science
- Cancer Treatment and Pharmacology
- Genetics, Bioinformatics, and Biomedical Research
Division of Undergraduate Education
2024
Winona State University
2006-2023
University of Wisconsin–River Falls
2014
University of Wisconsin–Milwaukee
2014
University of Iowa
1998-2012
University of Toronto
1998-2001
A student-centered learning technique, process-oriented, guided-inquiry (POGIL), has been developed as a pedagogical technique that facilitates collaborative and cooperative in the chemistry classroom. With use of this students enhance their higher-order thinking skills process synergistically. In addition, they develop positive relationships with other course. POGIL was recently implemented at mid-sized, comprehensive public institution used organic sequence. Comparisons ACS exam percentile...
AI technologies are rapidly pervading many areas of our world. AI-driven text generators such as ChatGPT at the forefront this due to their simplicity and accessibility. Their influence on higher education is already being observed, perceptions among faculty students vary widely. We have undertaken a cross-curriculum study ChatGPT's ability generate laboratory reports. AI-generated reports from general, organic, analytical, physical, inorganic, biochemistry courses were graded if they...
Chemical studies of organic extracts from cultures the coprophilous fungus Bombardioidea anartia have led to discovery bombardolides A−D (1−4), a series new antifungal and antibacterial metabolites. Three these metabolites (1−3) were obtained as inseparable pairs geometric isomers. A 3-substituted phenol (5) known compound asterriquinone B4 also encountered. The structures compounds 1−5 determined by analysis NMR MS data.
An in silico screen of the NIH Molecular Library Small Molecule Repository (MLSMR) ∼350000 compounds and confirmatory bioassays led to identification chaetochromin A (1) as an inhibitor botulinum neurotoxin serotype (BoNT A). Subsequent acquisition testing analogues 1 uncovered two compounds, talaroderxines (2) B (3), with improved activity. These are first fungal metabolites reported exhibit BoNT/A inhibitory
A discovery-based Grignard experiment for a second-year undergraduate organic chemistry course is described. The exclusive reagent formed by the reaction of 1-bromo-4-fluorobenzene (1) with Mg 4-fluorophenylmagnesium bromide (2), which treated either benzophenone or CO2 to produce corresponding fluorinated alcohol (3) benzoic acid (4), respectively. use dihalogenated requires students discern its reactivity synthesis. Students predict chemoselectivity formation based on C–X bond energies 1...
Chemical studies of the coprophilous fungus Ascodesmis sphaerospora (JS 247) have led to isolation arugosin F (1), a new antifungal and antibacterial metabolite. The structure was determined based on NMR MS data comparison with for known members class. A xanthone (2) also isolated.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAn Exploration of a Photochemical Pericyclic Reaction Using NMR DataSara M. Hein View Author Information Department Chemistry, Winona State University, Winona, MN 55987Cite this: J. Chem. Educ. 2006, 83, 6, 940Publication Date (Web):June 1, 2006Publication History Received3 August 2009Published online1 June 2006Published inissue 1 2006https://pubs.acs.org/doi/10.1021/ed083p940https://doi.org/10.1021/ed083p940research-articleACS PublicationsRequest...
Artificial intelligence (AI) tools are spurring rapid developments in academia, industry, and health care, free generative AI like ChatGPT can now perform some basic writing summary tasks. These technologies will likely continue to gain power capability, today's Chemistry majors may work at point settings augmented by AI. Instructors must adapt the availability of prepare our students for this evolving reality. In spring 2023, define a baseline chemistry education, group faculty from...