A5079347667- Mycobacterium research and diagnosis
- Genomics and Phylogenetic Studies
- Tuberculosis Research and Epidemiology
- Diagnosis and treatment of tuberculosis
- Actinomycetales infections and treatment
- Infectious Diseases and Mycology
Instituut voor Tropische Geneeskunde
2021-2024
The definition of a genus has wide-ranging implications both in terms binomial species names and also evolutionary relationships. In recent years, the
ABSTRACT Previous work reported unprecedented differences in the intrinsic vitro susceptibility of Mycobacterium tuberculosis complex (MTBC) to pretomanid (Pa) using Mycobacteria Growth Indicator Tube (MGIT) system. We tested 125 phylogenetically diverse strains from all known MTBC lineages ( 1 – 9 ) without Pa resistance mutations and four with as controls. This confirmed that MTBC, unlike most bacteria-antimicrobial combinations, displayed substantial relative technical variation MIC...
Species belonging to the Mycobacterium kansasii complex (MKC) are frequently isolated from humans and environment can cause serious diseases. The most common MKC infections caused by species M. (stricto sensu), leading tuberculosis-like disease. However, a broad spectrum of virulence, antimicrobial resistance pathogenicity these non-tuberculous mycobacteria (NTM) observed across MKC. Many genomic aspects that relate phenotypes not well elucidated. Here, we performed analyses collection 665...
Species belonging to the
Abstract The definition of a genus has wide ranging implications both in terms binomial species names and also evolutionary relationships. In recent years, the Mycobacterium been debated due to proposed split this into five new genera ( Mycolicibacterium, Mycolicibacter, Mycolicibacillus, Mycobacteroides an emended ). Since group contains many important obligate opportunistic pathogens, it is that any renaming does not cause confusion clinical treatment as outlined by nomen periculosum rule...