A5037965541- Exercise and Physiological Responses
- Adipose Tissue and Metabolism
- Histone Deacetylase Inhibitors Research
- Stress Responses and Cortisol
- Epigenetics and DNA Methylation
- Tryptophan and brain disorders
- Physical Education and Gymnastics
- Nerve injury and regeneration
- Cardiovascular and exercise physiology
- Autism Spectrum Disorder Research
- Muscle metabolism and nutrition
- Antioxidant Activity and Oxidative Stress
- Children's Physical and Motor Development
- Cerebral Palsy and Movement Disorders
- Childhood Cancer Survivors' Quality of Life
- Stroke Rehabilitation and Recovery
- Diet and metabolism studies
- Vitamin C and Antioxidants Research
- Neurogenesis and neuroplasticity mechanisms
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Sirtuins and Resveratrol in Medicine
- Ginkgo biloba and Cashew Applications
- Nuclear Receptors and Signaling
- Neuroendocrine regulation and behavior
- Phytochemistry Medicinal Plant Applications
Universidade Federal do Rio Grande do Sul
2014-2023
Universidade Federal de Ciências da Saúde de Porto Alegre
2016-2022
Centro Universitário Metodista IPA
2014-2022
Weatherford College
2021
Universidade Estadual Paulista (Unesp)
2021
Universidade de Caxias do Sul
2020
Universidade Metodista de São Paulo
2020
Methodist University
2017
Centro de Excelência em Bioinformática
2013
Hospital de Clínicas de Porto Alegre
2011-2012
Abstract Cerebral palsy (CP) is a disorder of locomotion, posture and movement that can be caused by prenatal, perinatal or postnatal insults during brain development. An increased incidence CP has been correlated to asphyxia maternal infections gestation. The effects exposure low doses bacterial endotoxin (lipopolysaccharide, LPS) associated not with anoxia (PA) in oxidative inflammatory parameters were examined cerebral cortices newborns pups. Concentrations TNF‐α, IL‐1, IL‐4, SOD, CAT DCF...
This study evaluated the response of global histone H4 acetylation (H4ac), deacetylase 2 (HDAC2) activity, as well production proinflammatory cytokines and monocyte phenotypes lean obese males after exercise. Ten ten sedentary men were submitted to one session strenuous exercise, peripheral blood mononuclear cells (PBMC) stimulated in vitro with lipopolysaccharide ( LPS ) . Global H4ac levels, HDAC2 activity PBMC, IL‐6, IL‐8, TNF‐ α analyzed. Monocyte phenotype was determined accordance...
It has been described that histone acetylation levels are decreased in several cellular and vivo neurodegeneration models as well normal brain aging, although the impact of aging process on deacetylases (HDAC) activity yet remains poorly understood. Therefore, our aim was to evaluate effect HDAC hippocampi frontal cortices from 3 18-months-old Wistar rats. The animals were decapitated at different times day, early morning afternoon. increased hippocampus aged group. Besides, hippocampal also...
Our aim was to compare the basal levels of plasma brain-derived neurotrophic factor (BDNF) and global histone H4 acetylation in peripheral blood mononuclear cells (PBMCs) healthy amateur runners (EXE group) with sedentary individuals (SED as well investigate acute effect a running race on these markers EXE group. Five days before race, all participants were submitted collection. On day, two samples collected group started immediately at end. In period, significant increase BDNF when compared...
The study described herein aimed to evaluate the impact of exercise on histone acetylation markers in striatum from Wistar rats at different stages development. Male were submitted two protocols: a single session treadmill (running 20 min) or moderate daily protocol min for 2 weeks). Striata aged 39 days postnatal (adolescents), 3 months (young adults), and (aged) used. induced persistent effects global HDAC activity only adolescent group, given that exercised showed decreased 1 18 h after...
The study aimed to compare the basal plasma levels of inflammatory markers (MCP-1, IL-1ra and IL-1β) in Parkinson Disease group (PDG) with control healthy subjects (control group, CG), as well investigate acute chronic effects an aquatic physiotherapy program on these biomarkers PDG. Firstly, a rest blood sampling was taken from antecubital vein PD CG. After, individuals were submitted supervisioned during 1 month, twice week (60 min/session). In order evaluate intervention biomarkers,...
Abstract In this study, we evaluated the effects of autologous serum collected after two types exercise on in vitro inflammatory profile and T cell phenotype resting peripheral blood mononuclear cells (PBMCs) obese men. Serum samples PBMCs were obtained from eight men who performed bouts—high intensity interval (HIIE) exhaustive session to voluntary fatigue—in a randomized cross-over trial. Pre-exercise incubated with 50% (collected before each bout) for 4 h. experiments revealed that...
Background: Emerging evidence point out that exercise is an epigenetic modulator and able to alter brain-derived neurotrophic factor (BDNF) levels in different populations. However, little known about the impact of on these markers well-trained aged individuals, making this research topic particularly relevant. Objectives: Therefore, current study aimed at investigating regular running practice global histone H4 acetylation brain–derived as well functional mobility healthy elderly males....