A5000982801- Diabetes Management and Research
- Diabetes and associated disorders
- Pancreatic function and diabetes
- HIV/AIDS Research and Interventions
- Diabetes Treatment and Management
- Wireless Networks and Protocols
- Adrenal Hormones and Disorders
- HIV/AIDS Impact and Responses
- Hormonal Regulation and Hypertension
- Diabetes Management and Education
- Adolescent Sexual and Reproductive Health
- Cardiac pacing and defibrillation studies
- Gene Regulatory Network Analysis
- Thyroid Cancer Diagnosis and Treatment
- Genetic factors in colorectal cancer
- Neurogenetic and Muscular Disorders Research
- Adolescent and Pediatric Healthcare
- COVID-19 and Mental Health
- Heart Failure Treatment and Management
- Food Security and Health in Diverse Populations
- RNA modifications and cancer
- Pharmacogenetics and Drug Metabolism
- Cancer-related Molecular Pathways
- COVID-19 Clinical Research Studies
- Metabolomics and Mass Spectrometry Studies
NYU Langone Health
2019-2025
Broad Institute
2024
Boston University
2024
Diabetes & Endocrine Associates
2020
Columbia University Irving Medical Center
2012-2018
University of the Witwatersrand
2018
Columbia University
2008
Yale University
2002
Diabetes mellitus is associated with increased COVID-19 morbidity and mortality, but there are few data focusing on outcomes in people type 1 diabetes.The objective of this study was to analyze characteristics adults diabetes for associations hospitalization.An observational multisite cross-sectional performed. care providers answered a 33-item questionnaire regarding demographics, symptoms, diabetes- COVID-19-related outcomes. Descriptive statistics were used describe the population,...
This large type 1 diabetes cohort study showed that insulin pump utilization has increased over time and use differs by sex, insurance type, race/ethnicity. Insulin was associated with more optimal A1C, of continuous glucose monitoring (CGM), lower rates diabetic ketoacidosis severe hypoglycemia. People who used an CGM had acute events than their counterparts without CGM. These findings highlight the need to improve access technology through provider engagement, multidisciplinary approaches,...
<p dir="ltr">Objective</p><p dir="ltr">Early initiation of continuous glucose monitor (CGM) after type 1 diabetes diagnosis has been associated with lower hemoglobin A1c (HbA1c) in single-institution studies. This multi-center study evaluated the association between timing CGM and HbA1c at 3 years post-diagnosis.</p><p><br></p><p dir="ltr">Research Design Methods</p><p dir="ltr">Data were obtained from T1D Exchange Quality...
OBJECTIVE Early initiation of continuous glucose monitor (CGM) after type 1 diabetes (T1D) diagnosis has been associated with lower hemoglobin A1C (HbA1c) in single-institution studies. This multicenter study evaluated the association between timing CGM and HbA1c at 3 years postdiagnosis. RESEARCH DESIGN AND METHODS Data were obtained from T1D Exchange Quality Improvement Collaborative (T1DX-QI) electronic health record database 25 pediatric centers included children adolescents ≤18 old...
<p dir="ltr">Objective</p><p dir="ltr">Early initiation of continuous glucose monitor (CGM) after type 1 diabetes diagnosis has been associated with lower hemoglobin A1c (HbA1c) in single-institution studies. This multi-center study evaluated the association between timing CGM and HbA1c at 3 years post-diagnosis.</p><p><br></p><p dir="ltr">Research Design Methods</p><p dir="ltr">Data were obtained from T1D Exchange Quality...
We used real-world electronic health record (EHR) data to examine HbA1c levels among children and adults with type 1 diabetes (T1D) who are classified as continuous glucose monitor (CGM) users after T1D diagnosis switch self-monitoring of blood (SMBG) during follow-up, versus people opt for SMBG CGM follow-up visits.We conducted an observational, case-crossover study using medical (EMR) from the Exchange Quality Improvement Collaborative. The primary outcome in this was HbA1c. Baseline were...
Spinal muscular atrophy is an autosomal recessive neurodegenerative disease caused by homozygous mutation to the survival motor neuron 1 (SMN1) gene. Historically, spinal has been considered almost exclusively affect function and of alpha neurons cord brainstem. With development animal models atrophy, presence widespread systemic abnormalities affecting brain, heart, pancreas repeatedly noted among animals with diminished protein expression. While these observations suggest similar possible...
South Africa is moving towards achieving elimination of mother-to-child transmission (eMTCT) but gaps remain in eMTCT programmes. Documenting successful outcomes health systems interventions to address these could encourage similar initiatives the future.We describe effectiveness a Quality Improvement Project (QIP) improve HIV retesting rates during pregnancy among women who had previously tested negative by redesigning clinic process. Eight poorly-performing clinics were selected and...
Abstract The Cancer Dependency Map aims to accelerate precision cancer medicine by identifying the landscape of vulnerabilities across all tumors. To address underrepresented types, we have optimized a genome-wide CRISPR KO screening pipeline, utilizing condensed Cas12a library, for patient-derived 3D models. Here, present characterization cohort ovarian models which consist subtypes along with treatment-resistant cancers. In particular, our organoid dataset includes low-grade serous...
Microbial colony growth is shaped by the physics of biomass propagation and nutrient diffusion, metabolic reactions that organisms activate as a function surrounding environment. While microbial colonies have been explored using minimal models motility, full integration metabolism still lacking. Here, building upon our framework for Computation Ecosystems in Time Space (COMETS), we combine dynamic flux balance modeling with collective demographic fluctuations to provide nuanced simulations
Objective: To present a case of adult-onset familial diabetes mellitus in which genetic etiology typical for neonatal was identified.Methods: We conducted whole-exome and Sanger sequencing, assessed clinical presentation family history, performed literature review.Results: A 40-year-old, thin woman presented with 10-year history mildly elevated fasting glucose A1C levels. Her mother had since her 40s is on insulin, daughter at age 21. The patient underwent sequencing were found to have...
To assess the potential of mindfulness practices to improve glycemic control in a diverse population young adults with type 1 diabetes (T1D), we examined cross-sectional association hemoglobin (Hb)A1c levels dispositional and adverse childhood experiences (ACEs). In 2017 conducted an online survey all 19-31 year olds (y/o) T1D receiving care at Columbia’s Naomi Berrie Diabetes Center. Responses were received from 423 752 (56%) patients linked medical record HbA1c. After adjusting for...
Introduction: With the large volumes of human immunodeficiency virus (HIV) positive patients in South Africa, one clinical management strategy has been to task shift. This means that previously hospi-centric HIV services have devolved primary health care (PHC) clinics. The referral pattern is true for paediatric as well. added complexity managing children, there was a concern research district children were not being optimally managed at PHC level.Method: A quality improvement project...
<p dir="ltr">This large type 1 diabetes cohort study showed that insulin pump utilization has increased over time and use differs by sex, insurance type, race/ethnicity. Insulin was associated with more optimal A1C, of continuous glucose monitoring (CGM), lower rates diabetic ketoacidosis severe hypoglycemia. People who used an CGM had acute events than their counterparts without CGM. These findings highlight the need to improve access technology through provider engagement,...
<p dir="ltr">This large type 1 diabetes cohort study showed that insulin pump utilization has increased over time and use differs by sex, insurance type, race/ethnicity. Insulin was associated with more optimal A1C, of continuous glucose monitoring (CGM), lower rates diabetic ketoacidosis severe hypoglycemia. People who used an CGM had acute events than their counterparts without CGM. These findings highlight the need to improve access technology through provider engagement,...
Introduction: With the large volumes of human immunodeficiency virus (HIV) positive patients in South Africa, one clinical management strategy has been to task shift. This means that previously hospi-centric HIV services have devolved primary health care (PHC) clinics. The referral pattern is true for paediatric as well. added complexity managing children, there was a concern research district children were not being optimally managed at PHC level.
 
 Method: A quality improvement...
In recent years, several new medications have proven useful in reducing heart failure–related morbidity and mortality. The result is a broader therapeutic armamentarium to treat both failure with reduced ejection fraction (HFrEF; left ventricular [LVEF] <40%) preserved (HFpEF; LVEF >50%).As pharmacological treatment of increases complexity cost, it has become more challenging for clinicians patients initiate maintain the multitude shown reduce mortality associated failure. addition, clinical...