Zachary Zirnhelt

ORCID: 0000-0003-4163-4184
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About
Contact & Profiles
Research Areas
  • COVID-19 Clinical Research Studies
  • COVID-19 epidemiological studies
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 diagnosis using AI
  • SARS-CoV-2 detection and testing
  • COVID-19 and healthcare impacts
  • Clostridium difficile and Clostridium perfringens research
  • Rabies epidemiology and control
  • Biosensors and Analytical Detection
  • Respiratory viral infections research
  • Infection Control in Healthcare
  • Vaccine Coverage and Hesitancy
  • Disaster Response and Management
  • Infection Control and Ventilation
  • Data-Driven Disease Surveillance

Minnesota Department of Health
2023-2024

During November 19-21, 2021, an indoor convention (event) in New York City (NYC), was attended by approximately 53,000 persons from 52 U.S. jurisdictions and 30 foreign countries. In-person registration for the event began on 18, 2021. The venue equipped with high efficiency particulate air (HEPA) filtration, attendees were required to wear a mask indoors have documented receipt of at least 1 dose COVID-19 vaccine.* On December 2, Minnesota Department Health reported first case...

10.15585/mmwr.mm7107a4 article EN MMWR Morbidity and Mortality Weekly Report 2022-02-17

While medical countermeasures in COVID-19 have largely focused on vaccinations, monoclonal antibodies (mAbs) were early outpatient treatment options for COVID-positive patients. In Minnesota, a centralized access platform was developed to offer mAbs that linked over 31,000 patients care during its operation. The website allowed patients, their representative, or providers screen the patient against Emergency Use Authorization (EUA) criteria and connect them with site if provisionally...

10.3389/fpubh.2023.1226935 article EN cc-by Frontiers in Public Health 2023-11-28

Wastewater-based epidemiology provides an approach for assessing the prevalence of COVID-19 in a sewer service area. In this study, SARS-CoV-2 RNA was measured 44 wastewater-treatment plants varying sizes that sampled approximately 67% population Minnesota, from September 2020 through December 2022. Various linear regression models were investigated to predict weekly case count concentrations under various transformation and normalization methods which we validated via cross-validation...

10.3390/w16040541 article EN Water 2024-02-09

Accurate and timely mortality surveillance is crucial for elucidating risk factors, particularly emerging diseases. We compared use of COVID-19 keywords on death certificates alone to identify deaths in Minnesota, USA, during 2020-2022, with a standardized definition incorporating additional clinical data. For analyses, we used likelihood ratio χ

10.3201/eid3007.231522 article EN cc-by Emerging infectious diseases 2024-06-27

Abstract SARS-CoV-2 transmission dynamics within households involving children are complex. We examined the association between paediatric index case (PIC) age and subsequent household among cases reported to Minnesota Department of Health March 2021 February 2022. In our primary analysis, we used logistic regression estimate odds ratios adjusted for race/ethnicity, sex, geographic region, disease severity with an unvaccinated PIC. performed a secondary analysis where PIC was eligible...

10.1017/s0950268824000918 article EN cc-by-nc-nd Epidemiology and Infection 2024-01-01

Abstract Background Older adults are at higher risk for hospitalization and death from COVID-19. The impact of COVID-19 reinfections on older is less clear. As more the population experiences least one infection, understanding factors associated with severe outcomes reinfection critical improving patient care. Methods We examined hospitalization, ICU admission, among MN residents aged 65+ experiencing 2nd infections (reinfection) during Omicron wave (12/26/2021-10/1/2022; n = 9311). first...

10.1093/ofid/ofad500.071 article EN cc-by Open Forum Infectious Diseases 2023-11-27
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