A5005545598- Insect Pest Control Strategies
- Ethnobotanical and Medicinal Plants Studies
- Insect and Pesticide Research
- Antibiotic Use and Resistance
- Natural Antidiabetic Agents Studies
- Helminth infection and control
- Malaria Research and Control
- Antibiotic Resistance in Bacteria
- Pesticide Residue Analysis and Safety
- African Botany and Ecology Studies
- Parasites and Host Interactions
- Antimicrobial Resistance in Staphylococcus
- Pneumonia and Respiratory Infections
- Papaya Research and Applications
- Pharmacological Effects of Medicinal Plants
- Cassava research and cyanide
- HIV-related health complications and treatments
- Pharmaceutical industry and healthcare
- HIV/AIDS drug development and treatment
- Pharmaceutical Practices and Patient Outcomes
- Natural product bioactivities and synthesis
- Pharmaceutical Quality and Counterfeiting
- Insect Resistance and Genetics
- Pharmacological Effects and Assays
- Agricultural pest management studies
Ghent University
2022-2024
Jimma University
2014-2023
Background . Drug resistant microorganisms lead to an increase in morbidity and mortality as they boost the risk of inappropriate therapy. Hence, data on antimicrobial resistance help define best possible treatment for individual patients. Therefore, this study aimed screen profile 3rd generation cephalosporin drugs Jimma University Specialized Teaching Hospital. Methods A hospital based prospective cross-sectional was conducted Hospital (JUSH) from April August 2016. The clinical samples...
Background The presence of poor quality medicines in the market is a global threat on public health, especially developing countries. Therefore, we assessed two commonly used anthelminthic drugs [mebendazole (MEB) and albendazole (ALB)] one antiprotozoal drug [tinidazole (TNZ)] Ethiopia. Methods/Principal Findings A multilevel stratified random sampling, with as strata different levels supply chain system Ethiopia, geographic areas government/privately owned outlets, was to collect samples...
Background . Currently, antimalarial drug resistance poses a serious challenge. This stresses the need for newer compounds. Carica papaya is used traditionally and showed in vitro activity. study attempted to evaluate vivo activity of C. mice. Methods In solvent fractions plant was carried out against early P. berghei infection Parasitemia, temperature, PCV, body weight mice were recorded. Windows SPSS version 16 (one-way ANOVA followed by Tukey’s post hoc test) data analysis. Results The...
A fast, accurate and reliable ultra-high performance liquid chromatography–tandem mass spectrometry (UHPLC-MS/MS) method was developed for simultaneous quantification of ivermectin (IVER), doramectin (DORA), moxidectin (MOXI) in bovine plasma. priority sample preparation the eradication possible infectious diseases to avoid travel restrictions. The based on protein precipitation using 1% formic acid acetonitrile, followed by Ostro® 96-well plate pass-through clean-up. simple straightforward...
Background and Objective: Many plant-derived compounds have been used as drugs, either in their original or semi-synthetic forms.Plant derived metabolites can also serve a lead compounds, which may be templates for the development of new drugs.Therefore, aim this study was to evaluate antimicrobial activities solvent fractions Vernonia amygdalina shoot apex Prunus africana bark against multidrug resistant bacterial strains.Materials Methods: The plant materials were obtained through...
Abstract Background Asymptomatic malaria transmission has become a public health concern across malaria-endemic Africa including Ethiopia. Specifically, Plasmodium vivax is more efficient at transmitting earlier in the infection and lower densities than falciparum . Consequently, greater proportion of individuals infected with P. can transmit without detectable gametocytaemia. Mass treatment livestock macrocyclic lactones (MLs), e.g., ivermectin doramectin, was suggested as complementary...
Outdoor biting, outdoor resting, and early evening biting of Anopheles arabiensis is a challenge in current malaria control elimination efforts Africa. Zooprophylaxis using livestock treated with macrocyclic lactones novel approach to zoophilic vectors. Therefore, the present study aimed investigate pharmacokinetics insecticidal efficacy ivermectin (IVER), doramectin (DORA), moxidectin (MOXI) subcutaneous (SC) formulations calves. The was conducted indigenous (Bos indicus) calves SC...
Highly active antiretroviral therapy (HAART) is the base for management of patients with HIV infection. On other hand, a switch in regimen could be compulsory because various reasons. Therefore, aim this study was to determine causes initial among adult HIV/ADIS patients. A retrospective cross-sectional conducted on patient information records those visited ART clinic since February 2013 January 2015 Asella Referral Hospital. Results: From 1468 patientsÂ’ medical reviewed, 221 them changed...
Misuse of antibiotics is the main cause for resistance development. The objective this study to assess patterns use and associated problems at Jimma Health Center. was conducted from February 25, 2016 March 2016. For analysis prescribing indicators retrospectively 295 patient charts that fulfills inclusion criteria were systematically selected a total 9800 health center registry department (from 8, 2015 2016). Prospectively 120 patients interviewed. average number drugs per encounter 2.2...
Outdoor biting, outdoor resting, and early biting of Anopheles arabiensis is a challenge in current malaria control elimination efforts Africa. Zooprophylaxis using livestock treated with macrocyclic lactones novel approach to zoophilic vectors. Therefore, the present study aimed investigate pharmacokinetics insecticidal efficacy ivermectin (IVER), doramectin (DORA), moxidectin (MOXI) subcutaneous (SC) formulations calves. The was conducted indigenous (Bos indicus) calves SC formulation at...
This study aimed to gather and document information on medicinal plants used in Ethiopia using an ethnomedicinal survey. The survey identified 80 species of belonging 39 botanical families by indigenous people Gimbo Didessa districts the Southwest for treatment 46 illnesses. majority were herbs. Leaves principal part plant preparation herbal remedies formulations. Most obtained from wild. oral route was most commonly mode administration medicine. Water salt frequently excipients remedies....
Pharmaceutical excipients derived from natural sources like resins are nowadays meritoriously used in the formulation of drugs. Resins origin have many advantages over chemically synthesized substances; they safer, nontoxic, less expensive, biodegradable, and widely available. To our knowledge, plants been not sufficiently explored for application pharmaceutical formulations. Thus, present study, a resin isolated Boswellia rivae Engl was characterized its potential use as excipient. Method....