Melissa S. Dulcich

ORCID: 0000-0003-4177-2317
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About
Contact & Profiles
Research Areas
  • Cancer, Stress, Anesthesia, and Immune Response
  • Anesthesia and Neurotoxicity Research
  • Neonatal and fetal brain pathology
  • Antioxidant Activity and Oxidative Stress
  • Pomegranate: compositions and health benefits
  • Tryptophan and brain disorders
  • Traumatic Brain Injury Research
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Cardiac Arrest and Resuscitation
  • Stress Responses and Cortisol
  • Immune cells in cancer
  • Sesame and Sesamin Research
  • Mitochondrial Function and Pathology
  • Cancer-related cognitive impairment studies
  • Cancer Research and Treatments
  • Cerebrospinal fluid and hydrocephalus
  • Neurogenesis and neuroplasticity mechanisms
  • Metabolism and Genetic Disorders
  • Retinoids in leukemia and cellular processes

Loma Linda University
2011-2021

Currently, NASA has plans for extended space travel, and previous research indicates that radiation can have negative effects on cognitive skills as well physical mental health. With long-term astronauts will be exposed to greater levels. Research shows an antioxidant-enriched diet may offer some protection against the cellular of provide significant neuroprotection from radiation-induced behavioral skill deficits. Ninety-six C57BL/6 mice (48 pomegranate fed 48 control) were irradiated with...

10.1155/2013/940830 article EN Evidence-based Complementary and Alternative Medicine 2013-01-01

To date, no stem cell therapy has been directed to specific recipients—and, conversely, withheld from others—based on a clinical or molecular profile congruent with that cell's therapeutic mechanism-of-action (MOA) for condition. We address this challenge preclinically prototypical scenario: human neural cells (hNSCs) against perinatal/neonatal cerebral hypoxic-ischemic injury (HII). demonstrate clinically translatable magnetic resonance imaging (MRI) algorithm, hierarchical region...

10.1016/j.celrep.2020.107622 article EN cc-by-nc-nd Cell Reports 2020-05-01

Prostate cancer (PCa) prevalence is higher in older men and poorer coping with psychosocial stressors effect prognosis. Yet, interactions between age, stress PCa progression are underexplored. Therefore, we characterized the effects of age isolation combined restraint (2 h/day) for 14 days post-tumor inoculation on behavior, tumor growth host defense immunocompetent, orthotopic RM-9 murine model. All mice were inoculated. Isolation/restraint increased sympathetic...

10.3389/fonc.2021.703848 article EN cc-by Frontiers in Oncology 2021-09-16
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