Sven Gombos

ORCID: 0000-0003-4177-526X
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About
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Research Areas
  • Plant nutrient uptake and metabolism
  • Nuclear Structure and Function
  • Genomics and Phylogenetic Studies
  • Plant-Microbe Interactions and Immunity
  • Microbial Metabolic Engineering and Bioproduction
  • Photosynthetic Processes and Mechanisms
  • Bioinformatics and Genomic Networks
  • RNA modifications and cancer
  • Potato Plant Research
  • Legume Nitrogen Fixing Symbiosis
  • ATP Synthase and ATPases Research
  • Pancreatic function and diabetes
  • Plant Micronutrient Interactions and Effects
  • RNA Research and Splicing
  • Studies on Chitinases and Chitosanases

University of Hohenheim
2021-2024

Plants must rapidly adapt to changes in nutrient conditions. Especially adaptations changing nitrogen environments are very complex involving also major adjustments on the protein level. Here, we used a size-exclusion chromatography-coupled mass spectrometry approach study dynamics of protein-protein interactions induced by transition from full nutrition starvation. Comparison interaction networks established for each condition revealed large overlap proteins which were part network, but...

10.1016/j.jprot.2021.104114 article EN cc-by-nc-nd Journal of Proteomics 2021-01-14

Plasmodesmata (PD) facilitate movement of molecules between plant cells. Regulation this is still not understood. are hard to study, being deeply embedded within cell walls and incorporating several membrane types. Thus, structure protein composition PD remain enigmatic. Previous studies identified lists with few validations, making functional conclusions difficult. We developed a scoring approach in iteration large-scale systematic localization, defining high-confidence proteome...

10.1111/nph.18730 article EN cc-by-nc New Phytologist 2023-01-13

Summary Plasmodesmata (PD) exchange small molecules, RNAs and proteins between plant cells with an exclusion limit for passive, non-specific transport. PD also facilitate the transport of specific cargo that may require chaperones or carriers The mechanisms underlying are not understood. nuclear pore complexes (NPC), nanometer size micropores similar properties. permeability barrier in NPCs is a phase separation domain formed by FG-nucleoporins (FG-NUP). Here we used bioinformatics,...

10.1101/2024.09.02.610746 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-09-03

<title>Abstract</title> Plasmodesmata (PD) exchange small molecules, RNAs and proteins between plant cells with an exclusion limit for passive, non-specific transport. PD also facilitate the transport of specific cargo that may require chaperones or carriers The mechanisms underlying are not understood. nuclear pore complexes (NPC), nanometer size micropores similar properties. permeability barrier in NPCs is a phase separation domain formed by FG-nucleoporins (FG-NUP). Here we used...

10.21203/rs.3.rs-5279839/v1 preprint EN cc-by Research Square (Research Square) 2024-10-25

Abstract Cells of multicellular organisms exchange nutrients, building blocks and information. In animals, this happens via gap junctions, in plants plasmodesmata (PD). PD have striking properties, translocating a large range molecules from ions, to metabolites, RNA proteins up 40 kDa. are hard characterize due being deeply embedded into cell walls the presence several membranes. While previous studies protein composition angiosperms identified lists proteins, few were validated. Here, we...

10.1101/2022.06.01.492581 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2022-06-01

NRT1.1, a nitrate transceptor, plays an important role in binding, sensing and dependent lateral root (LR) morphology. However, little is known about NRT1.1-mediated signaling transduction through plasma membrane (PM)-localized proteins. Through in-depth phosphoproteome profiling using membranes of Arabidopsis roots, we identified receptor kinase QSK1 H+-ATPase AHA2 as potential downstream components NRT1.1 mild low (LN)-dependent manner. QSK1, functional molecular link, physically interacts...

10.2139/ssrn.4593630 preprint EN 2023-01-01
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