- Computational Drug Discovery Methods
- Microbial Metabolic Engineering and Bioproduction
- Metabolomics and Mass Spectrometry Studies
- Genetics, Bioinformatics, and Biomedical Research
- Data Stream Mining Techniques
- Microbial Natural Products and Biosynthesis
- Plant biochemistry and biosynthesis
- vaccines and immunoinformatics approaches
- RNA and protein synthesis mechanisms
- Analytical Chemistry and Chromatography
- SARS-CoV-2 and COVID-19 Research
- AI and Big Data Applications
- Gene Regulatory Network Analysis
- Forensic Toxicology and Drug Analysis
- Pharmaceutical and Antibiotic Environmental Impacts
- Genomics and Phylogenetic Studies
- E-commerce and Technology Innovations
- Geophysical Methods and Applications
- Electromagnetic Simulation and Numerical Methods
- Electromagnetic Scattering and Analysis
- Advanced Technologies in Various Fields
Chinese Academy of Sciences
2020-2023
Shanghai Institutes for Biological Sciences
2020-2023
Shanghai Institute of Nutrition and Health
2020-2023
University of Chinese Academy of Sciences
2020-2023
Shandong Xiehe University
2020
Nanjing University of Posts and Telecommunications
2013
The rapid development of synthetic biology relies heavily on the use databases and computational tools, which are also developing rapidly. While many tool registries have been created to facilitate retrieval, sharing, reuse, no relatively comprehensive registry or catalog addresses all aspects biology.We constructed SynBioTools, a collection databases, experimental methods, as one-stop facility for searching selecting tools. SynBioTools includes methods extracted from reviews via SCIentific...
The mechanisms underlying drug addiction remain nebulous. Furthermore, new psychoactive substances (NPS) are being developed to circumvent legal control; hence, rapid NPS identification is urgently needed. Here, we present the construction of comprehensive database controlled substances, AddictedChem. This integrates following information on from US Drug Enforcement Administration: physical and chemical characteristics; classified literature by Medical Subject Headings terms target binding...
The 2019 novel coronavirus outbreak has significantly affected global health and society. Thus, predicting biological function from pathogen sequence is crucial urgently needed. However, little work been conducted to identify viruses by the enzymes that they encode, which are key propagation.We built a comprehensive scientific resource, SARS2020, integrates coronavirus-related research, genomic sequences results of anti-viral drug trials. In addition, we consensus sequence-catalytic model...
Living cell strains have important applications in synthesizing their native compounds and potential for use studies exploring the universal chemical space. Here, we present a web server named as Cell2Chem which accelerates search explored organisms, facilitating investigations of biosynthesis unexplored spaces. uses co-occurrence networks natural language processing to provide systematic method linking living organisms biosynthesized processes that produce these compounds. The platform...
Cosmetics form an important part of our daily lives, and it is therefore to understand the basic physicochemical properties, metabolic pathways, toxicological safe concentrations these cosmetics molecules. Therefore, comprehensive cosmetic ingredients bioinformatics platform (CCIBP) was developed here, which a unique database providing information on regulations, human pathways for molecules from major regions world, whilst also correlating plant in natural products. CCIBP supports...
ABSTRACT Summary The field of synthetic biology lacks a comprehensive knowledgebase for selecting target molecules according to their functions, economic applications and known biosynthetic pathways. We implemented ChemHub, containing >90 000 chemicals along with related biosynthesis information these that was manually extracted from >600 published studies by more than 100 people over the past 10 years. Availability implementation Multiple algorithms were enable pathway design...
In this paper, the finite-element boundary integral (FE-BI) method is applied to analyze electromagnetic scattering from three-dimensional objects with complex media located above a lossy half space.A fast numerical approach, UV method, employed decrease memory requirement and total CPU time for FE-BI solution.Numerical results are carried out so as validate our developed algorithm.