- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Congenital Heart Disease Studies
- Infective Endocarditis Diagnosis and Management
- Wound Healing and Treatments
- Laser Applications in Dentistry and Medicine
- Coronary Artery Anomalies
- Cardiac Structural Anomalies and Repair
- Vascular anomalies and interventions
- Cardiac and Coronary Surgery Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Aortic aneurysm repair treatments
- Mechanical Circulatory Support Devices
- Congenital Diaphragmatic Hernia Studies
- Pericarditis and Cardiac Tamponade
- Surgical Sutures and Adhesives
- Reproductive Biology and Fertility
- Pleural and Pulmonary Diseases
- Cancer Diagnosis and Treatment
- Biliary and Gastrointestinal Fistulas
- Cardiovascular and Diving-Related Complications
- Atrial Fibrillation Management and Outcomes
- Gastrointestinal disorders and treatments
- Cardiac tumors and thrombi
- Colorectal Cancer Surgical Treatments
University of Pavol Jozef Šafárik
2015-2025
National Institute of Cardiovascular Diseases
2018-2024
Technical University of Košice
2012
Detská Fakultná Nemocnica s Poliklinikou
2011
Institute of Biophysics
2009
Ocná klinika
2006
Objective: The purpose of this study was to evaluate, from the histological point view, effect diode laser irradiation on skin wound healing in Sprague-Dawley rats. Background Data: Various biological effects have been described different studies after low-level therapy (LLLT). Methods: Two parallel fullthickness incisions were performed back each rat (n = 49) and immediately sutured. After surgery, one exposed (continuous mode, 670 nm, daily dose 30 J/cm2), whereas not irradiated served as...
Aortic valve replacement (AVR) is the definitive therapy for patients with severe aortic stenosis (AoS). The aim of this work to compare effect a mechanical prosthesis (MP) and bioprosthesis (BP) on survival aged 50-65 years after AVR. retrospective analysis included 276 50 65 who had undergone isolated AVR AoS; 161 were implanted an MP 115 BP. Patient survival, adjusted age, gender risk parameters affecting was assessed. A subgroup performed 208 modern (prosthesis models that are no longer...
The aim of this study was to elaborate a histological model incisional skin wound healing in Sprague-Dawley rats. Under aseptic conditions two paravertebral full thickness incisions were performed on the back 42 anesthetized male Histological sections from tissue specimens stained by hematoxylin and eosin, van Gieson, PAS + PSD, Mallory's phosphotungstic azur eosin evaluated during first seven days after surgery. evaluation revealed that regeneration injured epidermis completed five...
The effect of Atropa belladonna L. (AB) aqueous extract on skin wound healing was studied in male Sprague-Dawley rats subjected to two parallel full-thickness incisions the back. Specimens for histological evaluation were collected days 2 and 5 whereas biomechanical testing, they day 5. In vitro study, a different concentration AB used test differentiation keratinocytes using panel selected antibodies, proliferation, cell survival 3T3 fibroblasts human umbilical vein endothelial cells...
Abstract Background and Objective Despite numerous hypotheses regarding the action of laser light, use low‐level therapy (LLLT) in ischemic reperfusion (I/R) injury is still being verified. The present study investigates effects irradiation (LLLI) on I/R musculus gracilis rats. Materials Methods flap was induced male adult Sprague–Dawley rats ( n = 84). Rats were subdivided depending treatment into four subgroups: (1) healthy group, (2) without irradiation, (3) R group irradiated only during...
Abstract OBJECTIVES Both aortic root remodelling and valve (AV) reimplantation have been used for valve-sparing replacement in patients with aneurysm or without regurgitation. There is no clear evidence to support one technique over the another. This study aimed compare basal ring annuloplasty versus on a multicentre level use of propensity-score matching. METHODS was retrospective international undergoing between 2010 2021. Twenty-three preoperative covariates (including dimensions...
The specific aim of this study was to measure the TS rat skin wounds during first week following surgical injury. Biomechanical and histological data were collected daily (days 1 7 surgery) from separate groups Sprague-Dawley rats (N = 12) each with two 3 cm long parallel incisions on back. immediately closed by four simple sutures. A control group 15) used obtain measurements unwounded skin. measured applying a ramp load until wound separation estimated dividing yield strength area. time...
<i>Background:</i> In this experimental study, simplicity of measurement and wound tensile strength wounds fixed by simple interrupted percutaneous suture (SIPS) intradermal running (IRS) were compared. <i>Methods:</i> Twenty-eight male Sprague-Dawley rats used for the experiment separated into two groups: SIPS group IRS group. Under general anesthesia, parallel full-thickness (4-cm) skin incisions made on back each rat. Wounds in closed using 4 sutures, whereas...
Infekčná endokarditída bola prvotne definovaná ako ochorenie pacientov s chlopňovými abnormalitami. V súčasnej dobe sú najrizikovejšou lokalitou vzniku infekčnej endokarditídy chlopňové protézy a iné implantované cudzorodé materiály.Kazuistika prezentuje prípad osemnásť ročnej pacientky anamnézou podstúpenia implantácie Amplatzerovho okluzora pred dvanástimi rokmi. Echokardiografické vyšetrenie poukázalo na prítomnosť v pravej predsieni srdca komunikáciou do ľavej predsiene poškodenie...
Klippel-Feil syndrome has been associated with cardiovascular malformations, but only 3 cases have reported to be aortic coarctation and surgical management is not defined. A 51-year old woman an aneurysm of the ascending aorta, hypoplastic arch at level left subclavian artery presented shortness breath 2 years after diagnosis. Imaging identified interim development a 7.2-cm coarctation. She underwent repair Dacron interposition graft under hypothermic circulatory arrest. continues do well...
The right aortic arch and coarctation are rare congenital anomalies with the incidence of 0.1% 0.03–0.04%. We present a case report 51-year-old woman aberrant left subclavian artery aorta post-stenotic aneurysm. Resection aneurysm replacement by tubular prosthesis was performed on partial cardiopulmonary bypass via femoral vessels. Partial is an applicable method for ensuring perfusion distal part body not contraindication this technique.
Súčasný výskyt ochorenia koronárnych artérii a chlopní srdca je významným rizikovým faktorom u pacientov podstupujúcich resekčný výkon na pľúcach. Možnosť vykonať konkomitantnú (simultánnu) operáciu aj pľúc pre týchto vhodnou možnosťou.V prezentovanom prípade bola vykonaná intervencia dvoch srdcových chlopniach, vykonaný bol trojnásobný aortokoronárny bypass resekcia pľúc. Podobný chirurgický doposiaľ publikovaný nebol.Kazuistika prezentuje 68-ročnú pacientku s trojcievnym koronárnym...
Objectives: The primary aim of this retrospective study was to evaluate short-term (one-to-six months) and mid-term (six-to-forty-eight results aortic valve-sparing procedures.The second endpoint compare the with group patients undergoing mechanical valve replacement during same period.Methods: Between April 2008 May 2012 at our institution, we treated 76 either ascending aorta/root aneurysm/dissection or isolated regurgitation.A total seventy-six surgery.Results: Analyzed parameters were...
Medzi najčastejšie primárne nádory pulmonálnej chlopne a artérie patrí schwanóm, myxóm, papilárny fibroelastóm, primárny choriokarcinóm sarkóm. Výskyt týchto histologických typov nádorov je veľmi raritný. klinické manifestácie tumorov dýchavica, bolesť na hrudi, kašeľ hemoptýza.Prezentovaná kazuistika 44-ročného muža s anamnézou zhoršujúcej sa dýchavice, febrilít, kašľa straty hmotnosti. Vyšetrenia zobrazovacími metódami poukázali veľkú nasadajúcu embóliu výtokovej časti pravej komory, kmeňa...
Medzirebrová herniácia pľúc je definovaná ako protrúzia pľúcneho tkaniva za normálne hranice hrudnej steny. Prvý prípad pľúcnej hernie opísal v roku 1499 Roland. Pomer získaných a vrodených pľúcnych hernií 4 : 1. Na základe anatomickej lokalizácie sú známe cervikálne, medzirebrové (interkostálne) diafragmatické formy herniácie. Rizikovou zónou posttraumatickej pooperačnej medzirebrovej dôsledku slabého svalového krytu predná stena hrudníka. Kazuistika prezentuje 71-ročného muža, ktorý pred 9...
Coronary artery anomalies are seen in less than 1% of the general population and 1.6% cardiac catheterization cases. The anomalous origin coronary from pulmonary is one four groups anomalies. incidence right 1 500,000 was first described 1882 by John Brook. This case report reports on a 67-year-old man with diagnosis asymptomatic artery. patient underwent surgery aortic valve because stenosis. A concomitant surgical procedure included repositioning to root sinus. discharged 12th...