A5055292276- Transplantation: Methods and Outcomes
- Immune Cell Function and Interaction
- Cardiac pacing and defibrillation studies
- Renal Transplantation Outcomes and Treatments
- Telemedicine and Telehealth Implementation
- Contact Dermatitis and Allergies
- Peptidase Inhibition and Analysis
- Healthcare Systems and Technology
- Pediatric health and respiratory diseases
- Drug-Induced Hepatotoxicity and Protection
- Pneumocystis jirovecii pneumonia detection and treatment
- Poisoning and overdose treatments
- Respiratory viral infections research
- Advanced MRI Techniques and Applications
- Healthcare cost, quality, practices
- Alcoholism and Thiamine Deficiency
- Heparin-Induced Thrombocytopenia and Thrombosis
- Immune responses and vaccinations
- Patient Satisfaction in Healthcare
- Health and Medical Research Impacts
- Food Allergy and Anaphylaxis Research
- Mechanical Circulatory Support Devices
- Health Systems, Economic Evaluations, Quality of Life
- T-cell and B-cell Immunology
Beth Israel Deaconess Medical Center
2024
Columbia University Irving Medical Center
2018-2022
Columbia University
2019-2021
Abstract Viral respiratory tract infections (VRTI) remain a leading cause of morbidity and mortality among infants young children. In mice, optimal protection to VRTI is mediated by recruitment effector T cells the lungs tract, subsequent establishment tissue resident memory (Trm), which provide long-term protection. These critical processes cell their role in disease pathogenesis, local protective immunity undefined pediatric VRTI. this study, we investigated responses upper (URT) lower...
Donor-specific antibodies (DSA) are associated with antibody-mediated rejection (AMR) and poor patient survival. In heart transplant, the efficacy of intermittent intravenous immunoglobulin (IVIg) in reducing de novo DSA levels treating AMR has not been characterized. We retrospectively studied a cohort 19 patients receiving IVIg for elevated examined changes graft function. Intermittent infusions were generally safe well tolerated. Overall, 23 62 total (37%) undetectable after treatment, 21...
Abstract Memory T cells are essential for optimal protection from previously encountered pathogens. Immune responses in infants lack the benefit of memory and intrinsically distinct those adults. Early life adaptive immune have been characterized by increased generation terminal effector subsets with decreased production long lived memory. Here we investigate origin utilizing flow cytometry immunohistochemistry to characterize proportions localization cell mucosal (intestine/lung) tissue...