A5065510659- Coronary Interventions and Diagnostics
- Cardiac Valve Diseases and Treatments
- Peripheral Artery Disease Management
- Cardiac Imaging and Diagnostics
- Venous Thromboembolism Diagnosis and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Cerebrovascular and Carotid Artery Diseases
- Vascular Procedures and Complications
- Acute Myocardial Infarction Research
- Renal and Vascular Pathologies
- Atrial Fibrillation Management and Outcomes
- COVID-19 Clinical Research Studies
- Central Venous Catheters and Hemodialysis
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Structural Anomalies and Repair
- Cardiac Arrest and Resuscitation
- Mechanical Circulatory Support Devices
- Cardiac and Coronary Surgery Techniques
- Cancer, Lipids, and Metabolism
- Chemotherapy-induced cardiotoxicity and mitigation
- Ultrasound in Clinical Applications
- Cardiac Arrhythmias and Treatments
- Acute Kidney Injury Research
Columbia University Irving Medical Center
2015-2024
NewYork–Presbyterian Hospital
2017-2024
New York Hospital Queens
2017-2023
Texas Health Dallas
2021-2023
Columbia University
2015-2023
Cardiovascular Institute of the South
2022-2023
Tufts University
2023
Cardiovascular Research Foundation
2017-2022
Vanderbilt University
2019
Henry Ford Hospital
2019
The Valve Academic Research Consortium (VARC), founded in 2010, was intended to (i) identify appropriate clinical endpoints and (ii) standardize definitions of these for transcatheter surgical aortic valve trials. Rapid evolution the field, including emergence new complications, expanding indications, novel therapy strategies have mandated further refinement expansion ensure relevance. This document provides an update most endpoint be used conduct research.Several years after publication...
<h3>Importance</h3> Use of transcatheter aortic valve replacement (TAVR) for severe stenosis is growing rapidly. However, to our knowledge, the durability these prostheses incompletely defined. <h3>Objective</h3> To determine midterm hemodynamic performance balloon-expandable heart valves. <h3>Design, Setting, and Participants</h3> In this study, we analyzed core laboratory–generated data from echocardiograms all patients enrolled in Placement Aortic Transcatheter Valves (PARTNER) 1 Trial...
Moderate or worse paravalvular regurgitation (PVR) post transcatheter aortic valve replacement (TAVR) is associated with increased mortality. The mechanisms by which this occurs are not fully understood.The aim of study was to determine the mechanism PVR leads outcomes.A total 1,974 intermediate-risk patients who received TAVR in PARTNER 2 trial and registries were grouped severity. Clinical echocardiographic outcomes compared.Overall 1,176 (60%) had none/trace, 680 (34%) mild, 118 (6%)...
Abstract Aims Left ventricular pressure overload is associated with activation of the cardiac renin–angiotensin system, which may contribute to myocardial fibrosis and worse clinical outcomes. We sought assess association between treatment angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs) at baseline outcomes in patients symptomatic, severe aortic stenosis (AS) undergoing transcatheter valve replacement (TAVR) PARTNER 2 trial registries. Methods...
B-type natriuretic peptide (BNP) is a cardiac neurohormone that secreted in response to ventricular volume expansion and pressure overload. There are conflicting data regarding the association between BNP levels outcomes after transcatheter aortic valve replacement (TAVR). We therefore sought assess baseline adverse patients with symptomatic, severe stenosis (AS), left ejection fraction (LVEF) ≥50%, undergoing TAVR PARTNER 2 Trial Registry.A total of 1782 were included analysis, was...
Intranasal opiate analgesia is the first choice in children presenting to paediatric emergency departments with severe pain. A prospective observational study was performed which showed that intranasal fentanyl a safe effective alternative diamorphine.
Abstract Objectives We sought to determine the 1‐year outcomes of patients receiving successful chronic total occlusion (CTO) percutaneous coronary intervention (PCI) procedures comparing subintimal versus intraplaque wire tracking patterns. Background CTO PCI utilizes both intraluminal and achieve revascularization. Intravascular ultrasound (IVUS) can be used precisely path tracking. Methods From 2014 2016, data from undergoing were collected in a single‐center database. The primary...
Percutaneous coronary intervention (PCI) in patients with advanced chronic kidney disease (CKD) is associated a high risk of contrast-induced nephropathy and resulting progression CKD to need for renal replacement therapy. Chronic total occlusions (CTO) PCI increasingly utilized the treatment refractory stable angina ischaemic heart failure. Recent studies have described feasibility 'minimal' or 'zero' contrast by employing intravascular imaging intra-coronary physiology guide successful...
Abstract Invasive aspergillosis ( IA ) contributes significantly to the burden of infectious complications in heavily immunosuppressed patients with acute leukemia. The infection is typically acquired via inhalation into respiratory tract, and lungs are most commonly involved. However, disseminated disease may occur reports isolated extrapulmonary suggest gastrointestinal tract likely an additional portal entry for this organism. We describe a case primary hepatic patient myelogenous did not...
Coronavirus disease 2019 (COVID-19) may predispose patients to venous thromboembolism (VTE). Limited data are available on the utilization of Pulmonary Embolism Response Team (PERT) in setting COVID-19 global pandemic. We performed a single-center study evaluate treatment, mortality, and bleeding outcomes who received PERT consultations March April 2020, compared historical controls from same period 2019. Clinical were abstracted electronic medical record. The primary endpoints inpatient...
Women have a higher rate of adverse events after mitral valve surgery. We sought to evaluate whether outcomes transcatheter edge-to-edge repair intervention by sex similar trends surgery.The primary outcome was 1-year major defined as composite all-cause mortality, stroke, and any bleeding in the overall study cohort. Patients who underwent for regurgitation with MitraClip system Society Thoracic Surgery/American College Cardiology Transcatheter Valve Therapy registry were evaluated. Linked...
Patients with acute pulmonary embolism (PE) present on a spectrum of clinical severity subset at risk for significant morbidity and mortality. Individuals without contraindications should be treated systemic anticoagulation therapy; however, advanced therapies including fibrinolysis, catheter-based approaches, surgical embolectomy, mechanical circulatory support may considered in the setting hemodynamic instability or deterioration. Catheter-based therapies, categorized into lytic non-lytic...