A5071062505- Phytochemical compounds biological activities
- Natural product bioactivities and synthesis
- Insect Pest Control Strategies
- Traditional and Medicinal Uses of Annonaceae
- Plant biochemistry and biosynthesis
- Insect and Arachnid Ecology and Behavior
- Insect and Pesticide Research
- Trypanosoma species research and implications
- Plant chemical constituents analysis
- Crystallization and Solubility Studies
- Plant and animal studies
- Essential Oils and Antimicrobial Activity
- X-ray Diffraction in Crystallography
- Ginger and Zingiberaceae research
- Phytochemistry and Biological Activities
- Synthesis of Organic Compounds
- Research on Leishmaniasis Studies
- Biological Activity of Diterpenoids and Biflavonoids
- Chemical synthesis and alkaloids
- Phytochemistry and Bioactivity Studies
- Phytochemicals and Antioxidant Activities
- Bioactive natural compounds
- Plant Pathogens and Fungal Diseases
- Insect Resistance and Genetics
- Chromatography in Natural Products
Universidade Federal de São Carlos
2015-2025
Universidade de São Paulo
2002-2024
Universidade Iguaçu
2024
Universidade de Ribeirão Preto
2005-2024
Instituto Butantan
2012-2022
University of Évora
2019
Universidade Federal de Goiás
2002-2017
Brazilian Computer Society
2016
Arab Foundations Forum
2015
Cultura
2012
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAntitumor agents from the cashew (Anacardium occidentale) apple juiceIsao. Kubo, Masamitsu. Ochi, Paulo C. Vieira, and Sakae. KomatsuCite this: J. Agric. Food Chem. 1993, 41, 6, 1012–1015Publication Date (Print):June 1, 1993Publication History Published online1 May 2002Published inissue 1 June 1993https://pubs.acs.org/doi/10.1021/jf00030a035https://doi.org/10.1021/jf00030a035research-articleACS PublicationsRequest reuse permissionsArticle...
ABSTRACT Nephrotoxicity is the main complication of gentamicin (GM) treatment. GM induces renal damage by overproduction reactive oxygen species and inflammation in proximal tubular cells. Phenolic compounds from ginger, called gingerols, have been demonstrated to antioxidant anti-inflammatory effects. We investigated if oral treatment with an enriched solution gingerols (GF) would promote a nephroprotective effect animal nephropathy model. The following six groups male Wistar rats were...
// Ana Carolina B.M. Martin 1, * , Angelina M. Fuzer Amanda B. Becceneri 1 James Almada da Silva 2 Rebeka Tomasin Delphine Denoyer 3 Soo-Hyun Kim 4 Katherine A. McIntyre 5 Helen Pearson 6 Belinda Yeo 7 Aadya Nagpal Xiawei Ling Heloisa S. Selistre-de-Araújo 8 Paulo Cézar Vieira Marcia R. Cominetti and Normand Pouliot 4, 5, 7, Department of Gerontology, Federal University São Carlos, SP, Brazil Chemistry, Metals in Medicine Laboratory, Centre for Cellular Molecular Biology (CCMB), Melbourne...
Verbascoside (1) is a phenylethanoid glycoside that has antileishmanial activity against Leishmania infantum and donovani. In this study, we verified the of 1 on amazonensis arginase inhibition. Compound showed an EC50 19 μM L. promastigotes competitive inhibitor (Ki = 0.7 μM). Docking studies were performed to assess interaction with at molecular level. Arginase enzyme polyamine biosynthesis pathway important parasite infectivity, results our study suggest could be useful develop new...
The focus of this study was the identification compounds from plant extracts for use in crop protection. This paper reports on toxic activity fractions leaf Ricinus communis L (Euphorbiaceae) and isolated active leaf-cutting ant Atta sexdens rubropilosa Forel its symbiotic fungus Leucoagaricus gongylophorus (Singer) Möller. main responsible against R were found to be fatty acids former ricinine ants.
Nine limonoids were isolated from Carapa guianensis and Cedrela fissilis. Among them, 1,2-dihydro-3beta-hydroxy-7-deacetoxy-7-oxogedunin is a new compound. Moreover, the assignments of some chemical shifts xyloccensin k have been corrected ¹H NMR data 7-deacetylgedunin assigned for first time. These assayed on Atta sexdens rubropilosa workers showing moderate insecticidal activities.
Scope Ginger has long been used in traditional A sian medicine to treat osteoarthritis. Indeed, scientific research reported that ginger derivatives ( GD s) have the potential control innate immune responses. Given widespread use and demonstrated properties of s, we set out study their anti‐inflammatory anticatabolic chondrocytes. Methods results 6‐shogaol (6‐ S ), most active , was obtained from ginger. 6‐ not toxic as measured by MTT assay, inhibited NO production IL ‐6 MCP ‐1 induced gene...
The structure of the glycosomal glyceraldehyde‐3‐phosphate dehydrogenase (gGAPDH) from Trypanosoma cruzi complexed with chalepin, a natural product Pilocarpus spicatus , has been determined by X‐ray crystallography to 1.95 Å resolution. is in apo form without cofactors subunits tetrameric gGAPDH asymmetric unit. Unequivocal density corresponding inhibitor was clearly identified one monomer. final refined model complex shows extensive conformational changes when compared native structure....
Abstract Extracts of different sesame plant ( Sesamum indicum ) Linnaeus organs inhibited the in vitro growth fungus Leucocoprinus gongylophorus (Möller) (= Rozites gongylophora Möller), which is cultivated by leaf-cutting ants species Atta sexdens rubropilosa Forel (Hymenoptera: Formicidae). The presence factor responsible for this inhibition was detected methanol or chloroform extracts and constant plant.
Abstract Astilbin was isolated in high yield from Dimorphandra mollis , and its insecticidal growth inhibiting activity by stomach ingestion were evaluated against Anticarsia gemmatalis Spodoptera frugiperda . The of astilbin, the weight reduction larval phase prolongation pupal phases verified for both species. identified on base NMR, MS physical data. © 2002 Society Chemical Industry
Citrus sinensis grafted on C. limonia produces a considerable number of compounds that are not common in both plants developed from germination seeds. The chemical profile scion and rootstock differ notably for absence the form flavonoids coumarins containing C5 prenyl groups attached to carbon atoms aromatic heterocyclic systems or oxygen. Only linear pyranocoumarins xanthyletin xanthoxyletin were found scion. This observation indicates prenylated once biosynthesized roots could have been...
The goal of the study was to evaluate ability filamentous fungi biotransform pentacyclic triterpene lupeol. microbial transformations were carried out in shake flasks different media. Experiments also run with control flasks. Samples each culture taken every 24 hours, extracted ethyl acetate, and analyzed by GC-MS. biotransformation lupeol Aspergillus ochraceus Mucor rouxii afforded two compounds culture, which detected cultures developed for more than seven days only Koch's K1 medium....
Cancer is the second leading cause of death worldwide and there epidemiological evidence that demonstrates this tendency emerging. Naringenin (NGEN) a trihydroxyflavanone shows various biological effects such as antioxidant, anticancer, anti-inflammatory, antiviral activities. It belongs to flavanone class, which represents flavonoids with C6-C3-C6 skeleton. Flavonoids do not exhibit sufficient activity be used for chemotherapy, however they can chemically modified by complexation metals...
Abstract This study describes the activity of five natural hydroxycinnamic acids and derived compound: caffeic ( 1 ), rosmarinic 2 chlorogenic 3 cryptochlorogenic 4 isoverbascoside 5 ). All compounds inhibited Leishmania amazonensis arginase with IC 50 —in range 1.5—11 μM. Compounds also showed against promastigotes L. = 61 (28–133) μM 14 (9–24) μM, respectively. Further computational studies applying molecular docking simulations were performed on competitive inhibitors to gain insight into...