A5051984247- Autoimmune and Inflammatory Disorders Research
- Healthcare professionals’ stress and burnout
- Neonatal Respiratory Health Research
- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Kawasaki Disease and Coronary Complications
- Immunodeficiency and Autoimmune Disorders
- Intergenerational Family Dynamics and Caregiving
- interferon and immune responses
- Ubiquitin and proteasome pathways
- Health and Well-being Studies
- COVID-19 and Mental Health
- Adenosine and Purinergic Signaling
- Urinary Tract Infections Management
- Neonatal and fetal brain pathology
- Family Caregiving in Mental Illness
- NF-κB Signaling Pathways
- Pediatric Urology and Nephrology Studies
- Immune Cell Function and Interaction
- Ocular Diseases and Behçet’s Syndrome
- Diversity and Career in Medicine
- Medical Education and Admissions
- COVID-19 Clinical Research Studies
- Dementia and Cognitive Impairment Research
King Saud bin Abdulaziz University for Health Sciences
2017-2025
King Abdulaziz Medical City
2022-2025
King Abdullah International Medical Research Center
2022-2025
National Guard Health Affairs
2022-2024
King Abdulaziz Hospital
2022
Introduction: Medical students tend to reduce their sleep, in an effort adjust and cope with workload stressful environment.This study estimated the prevalence of relationship between poor sleep quality stress among medical students.Methods: This cross-sectional was conducted using a stratified random sample male female King Saud bin Abdulaziz University for Health Sciences Riyadh, Saudi Arabia.A self-administered questionnaire distributed assess Pittsburgh Sleep Quality Index, level by...
To assess levels of burnout in medical students, and to explore the influence extracurricular activities on at a school Saudi Arabia.This cross-sectional study was conducted with first fourth year students King Saud bin Abdulaziz University for Health Sciences (KSAU-HS) Riyadh, Arabia. Socio-demographic, level (the Maslach Burnout Inventory-Student Survey, MBI-SS) participation data were collected using self-administered questionnaire. Statistical analyses performed Pearson's chi-square test...
OTU deubiquitinase with linear linkage specificity (OTULIN) regulates inflammation and cell death by deubiquitinating ubiquitin chains generated the chain assembly complex (LUBAC). Biallelic loss-of-function mutations causes OTULIN-related autoinflammatory syndrome (ORAS), while OTULIN haploinsuffiency has not been associated spontaneous inflammation. However, herein, we identify two patients heterozygous mutation p.Cys129Ser in OTULIN. Consistent ORAS, observed accumulation of chains,...
We aimed to assess depressive symptoms in caregivers of patients with dementia, taking into account variables such as severity sex, age, and financial state the patient. recruited 222 dementia from King Abdulaziz Medical City, Saudi Alzheimer's Disease Association, online, February June 2017, employed Patient Health Questionnaire depression, Blessed Dementia Scale dementia. The prevalence clinical depression among was 14.9%. Minimal were experienced by 96 (43.2%), moderate 45 (20.3%),...
Deficiency of adenosine deaminase 2 (DADA2) is a rare monogenic autoinflammatory disease resulting from biallelic loss-of-function mutations in ADA2 gene. It has variable clinical manifestations, some which can mimic Behçet's (BD). Herein, we present family three siblings diagnosed with DADA2, two whom were initially misdiagnosed as BD based on phenotype including positive human leukocyte antigen B51 (HLA-B*51). Gene mutational analysis was performed by whole exome (WES) and Sanger...
Abstract Purpose Major histocompatibility complex (MHC) class II deficiency is one of the combined immune disorders caused by defects in MHC regulatory genes leading to abnormal T cells development and function. Therefore, patients mainly present with increased susceptibility infections, diarrhea, failure thrive. In this report, we deficient patient a novel presentation Hemophagocytic Lymphohistiocytosis (HLH). Methods Immunophenotyping lymphocyte subpopulations HLA-DR expression was assess...
The Coronavirus disease 2019 (COVID-19) pandemic has emerged as a significant global health concern, impacting millions of individuals worldwide. However, there remains notable gap in the literature regarding pediatric studies, specifically focusing on children with rheumatic diseases and potential risk factors associated COVID-19 contraction this specific patient population. Patients are often undergoing immunemodulator/immunosuppressant therapies, which can further complicate their immune...
Febrile seizure is the most common convulsive event during childhood, but it generally considered benign.To estimate rate of epilepsy after first presentation febrile and to describe factors that can predispose children have subsequent their seizure.Retrospective chart review.A tertiary care center in Riyadh.All whose developed between 2009-2012, who were admitted pediatric wards.The prognostic for following seizure.Of 109 patients, 6 (5.5%, 95% CI: 2.1% - 11.6%) diagnosed with 5 46 months...
To determine the prevalence and risk factors of serious bacterial infections (SBIs) in infants 90 days younger with a confirmed respiratory tract infection (RTI).A retrospective cross-sectional study was carried out who were admitted to King Abdullah Specialized Children's Hospital, Riyadh, Saudi Arabia, from January 2019 December 2020, polymerase chain reaction (PCR)-proven RTI. Cultures urine, blood, cerebrospinal fluid reviewed patients' demographic information clinical presentation.Of...