A5029760599- Ion Transport and Channel Regulation
- Bioactive Compounds and Antitumor Agents
- Reproductive Physiology in Livestock
- Animal Diversity and Health Studies
- ATP Synthase and ATPases Research
- Drug-Induced Hepatotoxicity and Protection
- Muscle Physiology and Disorders
- Reproductive Biology and Fertility
- Enzyme function and inhibition
- Rabbits: Nutrition, Reproduction, Health
- Pharmacological Effects and Toxicity Studies
- Bee Products Chemical Analysis
- Essential Oils and Antimicrobial Activity
- Silymarin and Mushroom Poisoning
- Natural Antidiabetic Agents Studies
- Ion channel regulation and function
- Epilepsy research and treatment
- Sirtuins and Resveratrol in Medicine
- Chemotherapy-induced organ toxicity mitigation
- Plant Stress Responses and Tolerance
- Phytochemical compounds biological activities
- Virology and Viral Diseases
- Hemodynamic Monitoring and Therapy
- Heavy Metals in Plants
- Nigella sativa pharmacological applications
Qassim University
2019-2025
King Saud bin Abdulaziz University for Health Sciences
2024
Al-Salam Hospital
2024
National Guard Health Affairs
2024
King Abdulaziz Medical City
2024
Princess Nourah bint Abdulrahman University
2022
Riyadh Armed Forces Hospital
2022
University of Wisconsin–Madison
2018-2021
King Fahd Medical City
2020
IS practice
2019
Antioxidative, antidiabetic, and hypolipidemic properties of probiotic-enriched fermented camel milk (FCM) combined with Salvia officinalis L. leaves hydroalcoholic extract (SOHE) in streptozotocin-induced diabetes rats were investigated. Phytochemicals analysis antioxidant capacity indicated that S. contained high phenolics super activity. Subsequently, HPLC demonstrated 13 phenolic acids 14 flavonoids considerable amounts ferulic acid resveratrol as predominant, respectively. The...
Background and Aim: Diabetes mellitus (DM) is a chronic disease characterized by insulin insufficiency hyperglycemia, often leading to complications such as oxidative stress, dyslipidemia, organs damage. Sage (Salvia officinalis L.), medicinal plant with rich antioxidant bioactive compounds, has shown promise in managing diabetes related complications. This study investigates the antidiabetic, hypolipidemic, antioxidative effects of aqueous (AE) ethanolic (EE) extracts S. leaves at doses 400...
ABSTRACT (1) Background: Vaccine programs have been failing to provide complete immunity against the Newcastle disease virus (NDV). This study examines immunological responses live LaSota and Avinew (VG/GA) vaccines given through spray or drinking water broiler chickens; (2) Methods: The experimental vaccination included one unvaccinated control group four other groups of same size. There were three duplicates, each with 30 birds, amounting ninety birds. In addition status cellular humoral...
Kaff-e-Maryam (Anastatica hierochuntica L.) is extensively used to treat a range of health problems, most notably ease childbirth and alleviate reproductive system-related disorders. This study aimed evaluate the effect A. ethanolic (KEE), aqueous (KAE) extracts on CCl4-induced oxidative stress nephrotoxicity in rats using biochemical markers for renal functions antioxidant status as well histopathological examinations kidney tissue. contained 67.49 mg GAE g−1 total phenolic compounds (TPC),...
The high mortality of OvCa is caused by the wide dissemination cancer within abdominal cavity. cells metastasize to peritoneum, which covered mesothelial cells, and invade into underlying stroma, composed extracellular matrices (ECM) stromal cells. In a study using three-dimensional quantitative high-throughput screening platform (3D-qHTS), we found that β-escin, component horse chestnut seed extract, inhibited adhesion/invasion. Here, determine whether β-escin structurally similar compounds...
Abstract Purpose Major histocompatibility complex (MHC) class II deficiency is one of the combined immune disorders caused by defects in MHC regulatory genes leading to abnormal T cells development and function. Therefore, patients mainly present with increased susceptibility infections, diarrhea, failure thrive. In this report, we deficient patient a novel presentation Hemophagocytic Lymphohistiocytosis (HLH). Methods Immunophenotyping lymphocyte subpopulations HLA-DR expression was assess...
This study was carried out to evaluate the effects of dietary concentrate: forage (C: F) ratio on fat deposition, fatty acid composition, oxidative stability and mRNA expression levels sirtuins genes associated with adipose tissue metabolism subcutaneous in Black Tibetan sheep. Three diets different C: F (HC: 70:30, IC:50:50 LC: 30:70) were fed fifteen weaned male lambs (2-month-old, 10.05 ± 0.96 Kg). The experiment lasted for 120 d. Five from each group randomly selected slaughtered at end...
Abstract The Na + /K -ATPase (NKA) complex is the master regulator of membrane potential and a target for anti-cancer therapies. Here, we investigate effect drug-induced oxidative stress on NKA activity. natural product, plumbagin increases oxygen radicals through inhibition phosphorylation. As result, treatment results in decreased production ATP rapid increase intracellular radicals. We show that induces apoptosis canine cancer cells via stress. use this model to test Using whole-cell...
Abstract Oxidative stress inhibits Na + /K -ATPase (NKA), the ion channel that maintains membrane potential. Here, we investigate role of oxidative stress-mediated by plumbagin and atovaquone in inhibition NKA activity. We confirm inhibit proliferation three human (OVCAR-3, SKOV-3, TYKNu) one mouse (ID8) ovarian cancer cell lines. The oxygen radical scavenger, N-acetylcysteine (NAC), attenuates chemotoxicity atovaquone. Whole-cell patch clamping demonstrates outward inward current flowing...
Abstract Background Compared with corn, wheat contains higher crude protein, amino acids concentration. However, a mass of anti-nutritional factors, resulting in increased the digesta viscosity and impaired intestinal function ruminant. Objective This study aimed to investigate effects substitution different amounts for corn on hepatic metabolism Tibetan lamb. Methods Ninety lambs (Body weight = 12.37 ± 0.92 kg) were randomly assigned three groups: 0% diet (Control), 10% (Low group), 15%...
To determine the prevalence of depression and anxiety in adult multiple sclerosis patients attending tertiary facilities Riyadh, Saudi Arabia.This is a cross-sectional study conducted among MS Riyadh City, Arabia. A self-administered questionnaire was distributed at Prince Sultan Military Medical City Arabia between April 2020 January 2021. The consisted socio-demographic characteristics Hospital Anxiety Depression Scale (HADS). Univariate using Chi-square test multivariate regression...
The effect of feeding on diets supplemented with Silybum marianum L. dry seeds (SMS) growth performance, mortality percentage, biochemical parameters, the expression profile related genes, and genotoxic in Muscovy ducklings was evaluated during a brooding period 4 weeks. Two hundred forty one-day-old ducks were randomly assigned to four treatment groups (60 ducklings/group), first group fed basal diet no additives (control), second (4 g kg−1), third (8 fourth (12 kg−1) 0, 4, 8, 12 kg−1 SMS,...
The present study was carried out to evaluate the effects of partial replacement soybean with shrimp by-products (SBp) in African catfish (Clarias lazera) diets on productive (growth, digestibility, body composition, dressing yield, blood parameters, immunity) and economic performances. Therefore, 750 fingerlings (~20.0 g) were distributed into five groups 150 fingerlings/group three replicates (n = 50) per group. Group 1 fed a basal diet, while G2 G3 containing 25% SBp (autoclaved...
As hyperlipidemia has been associated with cardiovascular diseases, this study investigated the influence of probiotic-fermented camel and cow’s milk on blood lipid profiles in hypercholesterolemic rats. When tested, exhibited highest overall acceptance score flavor texture. Forty-eight male Wistar rats were divided into eight groups (n = 6). The first group served as normal control, while 2–8 fed a high-fat (HFD), high-cholesterol diet throughout experimental period treated different types...
The prevailing hot climate imposes heavy burdens on the productivity of camel, goat, and sheep herds raised in Gulf desert. Due to lack a reliable indicator for various subfertility statuses camel females, this study aimed investigate expression inhibin, TGFά, ILß, FSH, sex metabolic hormones, antioxidants fertility status females. Eighty-two subfertile five fertile females were admitted university clinic with complaint repeat breeding failed conception. animal's genital tracts examined...
Introduction Encephalitis, meningitis, and meningoencephalitis present significant challenges in clinical management owing to their diverse etiologies potential complications. A high suspicion index is critical for guiding treatment strategies improving patient outcomes. Understanding the demographic characteristics frequency of causes these conditions essential deliver optimized care. Objective This study aimed investigate epidemiological relative outcomes, including mortality, based on...
The objective of this study was to investigate the impact including hydroxytyrosol (HT) antioxidant on viability sperm after processes cooling and freezing. HT antioxidants were used in HF-20 extender at concentrations 1.25, 2.5, 5, 10