A5032087039- Metabolomics and Mass Spectrometry Studies
- Crime, Illicit Activities, and Governance
- Diet and metabolism studies
- Protein purification and stability
- Machine Learning in Healthcare
- Neuropeptides and Animal Physiology
- Mitochondrial Function and Pathology
- Adipose Tissue and Metabolism
- Alcoholism and Thiamine Deficiency
- Mass Spectrometry Techniques and Applications
- Immunotherapy and Immune Responses
- Liver Disease Diagnosis and Treatment
- Graphene and Nanomaterials Applications
- Nerve injury and regeneration
- Diabetes Treatment and Management
- Pancreatic function and diabetes
- Economic Sanctions and International Relations
- Management, Economics, and Public Policy
- Supramolecular Self-Assembly in Materials
- Advanced Proteomics Techniques and Applications
- Cancer, Lipids, and Metabolism
- RNA Interference and Gene Delivery
- Analytical Chemistry and Chromatography
- Corruption and Economic Development
- Child Welfare and Adoption
University of Rome Tor Vergata
2020-2024
The University of Melbourne
2023
IRBM Science Park
2022
University of Palermo
2015-2019
Glucose-responsive insulin-delivery platforms that are sensitive to dynamic glucose concentration fluctuations and provide both rapid prolonged insulin release have great potential control hyperglycemia avoid hypoglycemia diabetes. Here, biodegradable charge-switchable phytoglycogen nanoparticles capable of glucose-stimulated engineered. The "nanosugars" bearing glucose-sensitive phenylboronic acid groups amine moieties allow effective complexation with (≈95% loading capacity) form...
Abstract Context Metabolomics is becoming increasingly popular for detecting markers that indicate the presence of a specific disease. However, it usually applied to studying individual ailments, yielding results may not be directly relevant people with multiple health conditions. Objective Our study proposes different approach explore metabolic crosstalk between various disease states. Design, Setting, and Patients We conducted on subjects at medium high risk developing coronary artery...
Supramolecular assembly of polyphenols and biomacromolecules (proteins nucleic acids) has emerged as a versatile simple strategy to construct nanomaterials with biological activity. Here, we report finely control the supramolecular tannic acid oligonucleotides into uniform stable nanoparticles by exploiting thermal cycling acid. The equilibrium complexation is investigated, individual are resolved nanoscale resolution using stochastic optical reconstruction microscopy. incorporating cytosine...
LC‐HRMS‐based identification of the products peptide catabolism is key to drive design more stable compounds. Because catabolite a given can be very different from parent compound and other catabolites in terms physicochemical properties, it challenging develop an analytical method that allows recovery detection all parent‐related catabolites. The aim this study was investigate how matrix effect peptidic drugs their are affected by protein precipitation (PP) solid‐phase extraction (SPE)...
A new strategy that takes advantage of the synergism between NMR and UHPLC-HRMS yields accurate concentrations a high number compounds in biofluids to delineate personalized metabolic profile (SYNHMET). Metabolite identification quantification by this method result higher accuracy compared use two techniques separately, even urine, one most challenging characterize due its complexity variability. We quantified total 165 metabolites urine healthy subjects, patients with chronic cystitis,...
Purpose This paper aims to analyze the role of compliance in Italian banking system and verify its efficiency terms protection stability credibility financial institutions, comparing solutions adopted other European countries. Design/methodology/approach The research uses a comparative approach by examining different countries for finding analogies differences between them. Findings has discovered smaller development Compliance Function banks, whose risk frameworks are often still an...
Takotsubo syndrome (TTS) presents as an acute coronary characterized by severe left ventricular (LV) dysfunction and non-obstructive artery disease that typically shows spontaneous recovery within days or weeks. The mechanisms behind TTS are mainly related to beta-adrenergic overstimulation endogenous catecholamine surge, both of which could increase oxidative status may induce further deterioration cardiac function. Although several studies reported evidence inflammation stress overload in...
Purpose This paper aims to analyse the evolution of European anti-money laundering discipline passing from First Money Laundering Directive 91/308/EEC, that was only referred banks and financial intermediaries, has been furthermore extended some activities professions outside sector. The research examines different steps done buy Italian Legislation in field economic crime: at first Law n. 14/2003 3 February 2003 (Community 2002), they transposed 2001 2001/97/EC then 56/2004 20 2004,...
<title>Abstract</title> A new strategy that takes advantage of the synergism between NMR and LC-HRMS (SYNHMET), allows to obtain a unique list absolute concentrations 164 metabolites in urine, is presented. Metabolite identification quantification by this method one most difficult biofluids characterize, due complexity variability, more accurate than what can be obtained using two techniques separately. This result achieved without need for chemical reactions cross-check data types spectra,...
Purpose – This paper aims to analyse the fundamental principles of main international conventions against use drug and verify if it would be preferable let European Member States adopt specific measures according own needs at a national level. Design/methodology/approach The research uses comparative approach by examining different legislations in respect discipline for finding analogies differences between them. Findings has discovered wide variation criteria triggering legislative response...
Insulin Delivery In article number 2210392, Christoph E. Hagemeyer, Francesca Cavalieri, and co-workers report how biodegradable charge-switchable phytoglycogen nanoparticles with glucose-sensitive phenylboronic acid groups amine moieties can be engineered to form nanocomplexes insulin for its rapid efficient glucose-responsive delivery. Subcutaneous injection of in two distinct diabetic mouse models helps maintain normal glucose levels up 13 h.
Purpose This paper aims to analyze the main international rules against economic crime and verify if Italian legislation provides for appropriate measures according own needs at a national level. Design/methodology/approach The research uses comparative approach by examining existing legislations on global, European level finding analogies differences between them. Findings has discovered wide variation in legislative interventions crimes kind of imposed sanctions. Nevertheless, there seems...
Purpose This paper aims to outline the Italian framework of rules against economic crime and verify if legislation provides for appropriate effective measures according own needs both at a national European level. Design/methodology/approach The uses comparative approach by examining legal systems finding analogies differences between them. Findings study has revealed need greater international harmonisation criminal laws penalties as well transnationality cuts chance success every strategy,...