A5101693891- Animal Virus Infections Studies
- Animal Nutrition and Physiology
- Virus-based gene therapy research
- Viral gastroenteritis research and epidemiology
- Immunotherapy and Immune Responses
- T-cell and B-cell Immunology
- Probiotics and Fermented Foods
- Aquaculture disease management and microbiota
- Microbial infections and disease research
- Animal Disease Management and Epidemiology
- Immune Cell Function and Interaction
- Blood groups and transfusion
- MicroRNA in disease regulation
- Ferroptosis and cancer prognosis
- GABA and Rice Research
- Identification and Quantification in Food
- Pancreatic and Hepatic Oncology Research
- Hematopoietic Stem Cell Transplantation
- Salmonella and Campylobacter epidemiology
- Escherichia coli research studies
- Infant Nutrition and Health
- Coccidia and coccidiosis research
- melanin and skin pigmentation
- Meat and Animal Product Quality
- Food Quality and Safety Studies
Washington University in St. Louis
2023
Tianjin Medical University
2020
Shandong Province Animal Husbandry and Veterinary Bureau
2017
Virginia–Maryland College of Veterinary Medicine
2011-2012
University of Maryland, College Park
2011-2012
BGI Group (China)
2011
ABSTRACT Type I interferons (IFNs) IFN-α/β play an important role in innate immunity against viral infections by inducing antiviral responses. Porcine reproductive and respiratory syndrome virus (PRRSV) inhibits the synthesis of type IFNs. However, whether PRRSV can inhibit IFN signaling is less well understood. In present study, we found that interferes with pathway. The transcript levels IFN-stimulated genes ISG15 ISG56 protein level signal transducer activator transcription 2 (STAT2)...
Our study investigates the comparative effects of n-6 and n-3 polyunsaturated fatty acids (PUFAs) on immune modulation inflammation using a fat-1 transgenic mouse model capable endogenously converting PUFAs to PUFAs. The results show that PUFAs, particularly arachidonic acid (AA), promote pro-inflammatory environment by increasing production inflammatory mediators, including leukotrienes prostaglandins, while upregulating NFκB signaling NLRP3 inflammasome activation. In contrast, such as...
Pancreatic cancer is one of the most malignant tumors digestive system, with insidious, rapid onset and high mortality. The 5-year survival rate only 10%. Therefore, in-depth exploration potential mechanism affecting prognosis pancreatic cancer, search for biomarkers that can effectively predict are practical clinical importance. mRNA sequencing data, miRNA methylation data SNP patients available in Cancer Genome Atlas (TCGA) were used analysis to identify significantly affect patients....
Nine novel human leukocyte antigen‐DRB1 (HLA‐DRB1) alleles were identified in Chinese individuals.
In order to investigate the immunomodulatory effect of Robinia pseudoacacia Polysaccharides (RPPS) on vaccine against Infectious Bronchitis (IB) in immunosuppressive chickens, artificial leukemia chicken model was established and then IB live (H120 strain) immunized. The efficacy RPPS determined by antibody titer, lymphocyte transformation rate peripheral blood, CD4 + CD8 T levels cytokine serum. results showed that could not only enhance immune but also improve immunity chickens. Thus,...
Reticuloendotheliosis virus (REV) infection has frequently affected the poultry industry in recent years. The with REV weakens immune responses of infected poultry. It is reported that Enteromorphaclathrata polysaccharides are capable regulating function. In order to investigate immuno regulatory effects (EPS) on response REV-infected broilers a live attenuated Newcastle disease (ND) vaccine. Broilers were intraperitoneally injected at one day age, subcutaneously EPS 2 days and vaccinated by...