A5065193019- Cutaneous Melanoma Detection and Management
- Cutaneous lymphoproliferative disorders research
- Autoimmune Bullous Skin Diseases
- Nail Diseases and Treatments
- Cancer and Skin Lesions
- Nonmelanoma Skin Cancer Studies
- melanin and skin pigmentation
- Urticaria and Related Conditions
- Melanoma and MAPK Pathways
- Dermatology and Skin Diseases
- Skin Protection and Aging
- Acne and Rosacea Treatments and Effects
- Vascular Tumors and Angiosarcomas
- Eosinophilic Disorders and Syndromes
- Genetic and rare skin diseases.
- Contact Dermatitis and Allergies
- Drug-Induced Adverse Reactions
- Sarcoma Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Tumors and Oncological Cases
- Histiocytic Disorders and Treatments
- Autoimmune and Inflammatory Disorders
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Skin Diseases and Diabetes
- Dermatologic Treatments and Research
Chonnam National University Hwasun Hospital
2006-2025
Chosun University
2025
Chonnam National University Hospital
2015-2024
Chonnam National University
2012-2024
Massachusetts General Hospital
2024
Harvard University
2024
Memorial Sloan Kettering Cancer Center
2024
Catholic University of Korea
2013-2021
University of Pennsylvania
2016
Robert Bosch (Australia)
2009
Predicting clinical behavior of atypical Spitz tumors remains problematic. In this study, we assessed interobserver agreement diagnosis by 13 expert dermatopathologists for (n=75). We determined which histomorphologic features were most heavily weighted their diagnostic significance the experts and also had a statistically significant correlation with outcome. There was low among in categorizing lesions as malignant versus nonmalignant (κ=0.30). The that given were: consumption epidermis,...
The pathogenesis of acral melanoma remains unclear, even though trauma may be a predisposing factor. A study about the association long-term physical stress with incidence and spreading patterns through detailed anatomic mapping important to understand unique features melanoma.To analyze epidemiologic clinicopathologic characteristics evaluate how or pressure strength influences based on analysis differences in incidence, prognosis distinct site (weight non-weight-bearing portion sole,...
Recent studies indicated that the autoimmunity of vitiligo exerts effects on cells other than melanocytes, which confer reduced risks both melanoma and nonmelanoma skin cancers in patients with vitiligo. However, risk internal malignancy has not been elucidated.We conducted a population-based retrospective cohort study using data from Korean National Health Insurance claims database obtained January 2007 to December 2016. All age 20 years or older who had at least two contacts physician 2009...
Although rosacea is a chronic cutaneous inflammatory disorder that's commonly seen in adults, the etiology and pathogenesis of illness remain unclear. A well established diagnostic classification grading system may play critical role performing research it would serve as reference clinical field. We sought to classify patients with new standard we wanted determine peculiar features relationships each subtype. also analyzed between degree sun exposure reviewed medical records photos 168 who...
Little is known about factors affecting the quality of life (QoL) patients with vitiligo, and previous studies have shown conflicting results. To explore QoL vitiligo to identify QoL. A nationwide questionnaire‐based study was conducted 1123 recruited from 21 hospitals in Korea July 2015 June 2016. Data were collected using a structured questionnaire for demographic information Skindex‐29 instrument. Mild or severely impaired assessed according each domain (symptoms, functioning emotions)...
Drivers of Spitz neoplasms include activating point mutations in HRAS and Spitz-associated genomic fusions. It has become evident that some BRAF -mutated melanocytic can morphologically mimic tumors (STs). These have been termed mutated spitzoid (BAMS). In this study, 17 experts from the International Melanoma Pathology Study Group assessed 54 cases which included 40 BAMS 14 true STs. The participants reviewed blinded to data selected among several diagnostic options, including BAMS, ST,...
<i>Background:</i> Anagen effluvium is a common side effect of chemotherapy, but few studies have examined its clinical characteristics. <i>Objective:</i> This study was aimed at evaluating the hair loss caused by chemotherapeutic agents. <i>Methods:</i> Sixty-four patients with anagen were evaluated in study. Chemotherapeutic agents classified into 5 different groups. The pattern analyzed when specific involvement hairline obvious....
Giant congenital melanocytic naevi (GCMN) are known risk factors for the development of melanoma. However, melanoma among Asians is rarely evaluated.To evaluate clinical characteristics and from GCMN in Koreans, we performed a nationwide retrospective cohort study Korea. were defined as those comprising ≥5% body surface area children or measuring ≥20cm adults.In total, 131 patients with enrolled, mean age 10·3years (range: birth-70years).The posterior trunk was most common site (67, 51·1%),...
// Yun Hyun Huh 1 , Sena Oh 1, 2 Yu Ra Yeo In Hee Chae So Kim Ji Shin Lee 3 Sook Jung 4 Kyu Yeong Choi 5 Je-Hwang Ryu 6 Chang-Duk Jun Woo Keun Song Bio Imaging and Cell Dynamics Research Center, Gwangju Institute of Science Technology, Gwangju, Korea School Life Sciences, Department Pathology, Chonnam National University Hwasun Hospital, Hwasun, Dermatology, The Division Natural Medical College Health Science, Chosun University, Dental Center for Biomineralization Disorders, Dentistry,...
Propionibacterium acnes naturally produces endogenous porphyrins that are composed of coproporphyrin III (CPIII) and protoporphyrin IX (PpIX). Red light alone photodynamic therapy (PDT) improve acne vulgaris clinically, but there remains a paucity quantitative data directly examine the bactericidal effects result from PDT on P. itself in vitro. The purpose this study was to measure difference 5-aminolevulinic acid (ALA)-PDT with red blue acnes. were cultured under anaerobic conditions...
Background: Bullous pemphigoid (BP) is a common autoimmune-mediated blistering skin disease that significantly associated with mortality and morbidity.However, few studies regarding the comorbidity profiles of BP have been reported in Korea.Objective: To evaluate compare mortality, profiles, risk factors between patients who visited our clinic an age-matched general population Korea.Methods: We retrospectively evaluated 103 diagnosed 2006 2013 at Chonnam National University Hospital Gwangju,...
Atypical Spitzoid melanocytic tumors are diagnostically challenging. Many studies have suggested various genomic markers to improve classification and prognostication. We aimed assess whether next-generation sequencing using the Tempus xO assay assessing mutations in 1711 cancer-related genes performing whole transcriptome mRNA for structural alterations could diagnostic agreement accuracy neoplasms with histologic features. Twenty expert pathologists were asked review 70 consultation level...
Background The increased expression of programmed cell death ligand 1 (PD-L1) on a subset immune cells in the peripheral blood has been frequently observed patients with cancer, suggesting relationship PD-L1 tumor tissues. In this study, we investigated mechanisms underlying various types cancer. Methods populations was analyzed mononuclear 112 non-small lung cancer (NSCLC) using flow cytometry. A mouse model X-ray-induced acute thrombocytopenia used to investigate between thrombopoiesis and...
We aimed to investigate the causes and clinical features of compressive optic neuropathy in Koreans. analyzed medical records patients diagnosed with from March 2014 December 2023 determine cause nerve compression, symptoms symptom patterns at first visit, accompanying symptoms, types visual field defects, prognosis after surgery. In addition, results tests optical coherence tomography were positivity rate each test factors affecting results. A total 73 neuropathy, most common was pituitary...
Clear cell sarcoma (CCS), also known as malignant melanoma of soft parts, is a rare malignancy constituting approximately 1% all soft-tissue sarcomas. It occurs predominantly in the lower extremities young adults, manifesting deep, painless, slow-growing mass. CCS sometimes confused with other types because its melanocytic differentiation. Although BRAF and KIT mutations are well-known tumour-promoting frequently found cutaneous melanoma, they or absent CCS. We present two cases different...